Genes News and Research

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Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

Severe COVID-19 may result in premature aging in recovered patients

As COVID-19 has been found to cause frontal cortex impairment similar to aging, the scientists in a recent study attempted to investigate if severe COVID-19 resulted in aging-related molecular signatures in the brain. The findings from this study are published as a preprint on the medRxiv* server.

28 Nov 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

Genetic ancestry can explain population-level differences in immune response to the flu virus

A new study aimed at explaining differential susceptibility to viral epidemics reveals that ancestry and associated genetic variation can explain population-level differences in the immune response to the flu virus and perhaps also to COVID-19.

26 Nov 2021

WHO designates Omicron (B.1.1.529) as SARS-CoV-2 Variant of Concern

The Technical Advisory Group on SARS-CoV-2 Virus Evolution (TAG-VE) is an independent group of experts that periodically monitors and evaluates the evolution of SARS-CoV-2 and assesses if specific mutations and combinations of mutations alter the behavior of the virus.

26 Nov 2021

Discovering a new gene in monkeys that could help to develop new antivirals

We spoke to Dr. Nels Elde about his latest research that led to the discovery of a new gene in monkeys that could help to develop new antivirals.

26 Nov 2021

Immune response to influenza virus influenced by genetic ancestry

New research at the University of Chicago has found differences in immune pathway activation to influenza infection between individuals of European and African genetic ancestry.

25 Nov 2021

Research reveals how disordered protein interaction orchestrates gene expression

A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered a new piece of the puzzle of how gene expression is orchestrated.

25 Nov 2021

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

LMU immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.

25 Nov 2021

International collaboration secures €1M grant to investigate new treatment target for lymphoma

An international collaboration involving researchers from Queen Mary University of London, Memorial Sloan Kettering Cancer Center, New York and Dana-Farber Cancer Institute, Boston has secured a €1M research grant from Dutch blood cancer charity, Lymph&Co, to investigate a new treatment target for lymphoma.

25 Nov 2021

MIT scientists discover how molecular clusters interact with chromosomes in the nucleus

A cell stores all of its genetic material in its nucleus, in the form of chromosomes, but that's not all that's tucked away in there. The nucleus is also home to small bodies called nucleoli - clusters of proteins and RNA that help build ribosomes.

25 Nov 2021

Serum SARS-CoV-2 antigen: A better predictor of COVID-19 severity

In this perspective, a new study published on the medRxiv* preprint server analyzed the clinical efficacy of two serum antigen tests to identify SARS CoV-2 infection and evaluate the kinetics of serum nucleocapsid (N) antigen in severe and non-severe patients for disease severity prediction.

24 Nov 2021

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Scientists have hypothesized that the number of immune cells and the amount of cytokines produced in response to SARS-CoV-2 infection in pregnant women change in accordance with the timing of maternal infection in pregnancy. This study is available on the bioRxiv* preprint server.

24 Nov 2021

Acute SARS-CoV-2 infection during pregnancy associated with placental ACE2 shedding

A new study, published on the bioRxiv* preprint server, hypothesized that ACE-2 expression and ADAM17 activity in the placenta is affected by the timing of SARS-CoV-2 infection of the mother.

24 Nov 2021

Drug-resistant bacteria are quickly outpacing new antibiotic development

Experts predict that without intervention, the problem of multidrug-resistant bacterial infections could be catastrophic by 2050, killing nearly 10 million people each year.

24 Nov 2021

Study uncovers important genetic predispositions for acute myeloid leukemia

The National Center for Tumor Diseases Dresden is a joint institution of the German Cancer Research Center, the University Hospital Carl Gustav Carus Dresden, Carl Gustav Carus Faculty of Medicine at TU Dresden and the Helmholtz-Zentrum Dresden-Rossendorf.

24 Nov 2021

New technique may be a significant leap forward in the understanding of human cells

Most human diseases can be traced to malfunctioning parts of a cell — a tumor is able to grow because a gene wasn't accurately translated into a particular protein or a metabolic disease arises because mitochondria aren't firing properly, for example. But to understand what parts of a cell can go wrong in a disease, scientists first need to have a complete list of parts.

24 Nov 2021

Genes News and Research

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Severe COVID-19 may result in premature aging in recovered patients

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

Genetic ancestry can explain population-level differences in immune response to the flu virus

WHO designates Omicron (B.1.1.529) as SARS-CoV-2 Variant of Concern

Discovering a new gene in monkeys that could help to develop new antivirals

Immune response to influenza virus influenced by genetic ancestry

Research reveals how disordered protein interaction orchestrates gene expression

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

International collaboration secures €1M grant to investigate new treatment target for lymphoma

MIT scientists discover how molecular clusters interact with chromosomes in the nucleus

Serum SARS-CoV-2 antigen: A better predictor of COVID-19 severity

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Acute SARS-CoV-2 infection during pregnancy associated with placental ACE2 shedding

Drug-resistant bacteria are quickly outpacing new antibiotic development

Study uncovers important genetic predispositions for acute myeloid leukemia

New technique may be a significant leap forward in the understanding of human cells

The antimicrobial properties of the lungfish cocoon

Experimental compound reduces diabetic complications in mice

Study finds rhinovirus reduces SARS-CoV-2 replication in airway epithelial cells

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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