Infectious Diseases News and Research

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Profectus begins Phase 1 clinical study of VesiculoVax-vectored Ebola virus vaccine

Profectus BioSciences, Inc., a clinical-stage vaccine company developing novel vaccines for the prevention and treatment of infectious diseases and the treatment of cancer, announced today the initiation of a Phase 1 clinical study of Profectus' VesiculoVax-vectored Ebola virus vaccine.

19 Jan 2016

Researchers suggest ways to make TB drugs more efficacious against mutations

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed three-dimensional structure of the drugs interacting with an essential enzyme in the TB germ, also reveal why some TB drugs are more potent than others and suggest how drug developers can make fluoroquinolones more efficacious against mutations that make the lung disease drug resistant.

19 Jan 2016

New clinical imaging method may enable doctors to tackle lung infections

A new clinical imaging method developed in collaboration with a University of Exeter academic may enable doctors to tackle one of the main killers of patients with weakened immune systems sooner and more effectively.

19 Jan 2016

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

We've all seen the headlines. "Man found to be shedding virulent strain of polio"; "Virulent flu strain in Europe hits the economy"; "Most virulent strain of E. coli ever seen contains DNA sequences from plague bacteria."

19 Jan 2016

UGA study helps solve mystery of how African trypanosomes communicate

While scientists have known for years that African trypanosomes cause sleeping sickness, they've been left scratching their heads as to how these tiny single-celled organisms communicate. A University of Georgia study, published Jan. 14 in the journal Cell, helps solve this mystery.

18 Jan 2016

Gene linked to autism lays groundwork for crucial brain structure during prenatal development

A gene linked to mental disorders helps lays the foundation for a crucial brain structure during prenatal development, according to Salk Institute research published January 14, 2016 in Cell Reports.

18 Jan 2016

Large-scale clinical trial to evaluate dengue vaccine launched in Brazil

A large-scale clinical trial to evaluate whether a candidate vaccine can prevent the mosquito-borne illness dengue fever has been launched in Brazil. The vaccine, TV003, was developed by scientists in the laboratory of Stephen Whitehead, Ph.D., at NIH's National Institute of Allergy and Infectious Diseases (NIAID).

17 Jan 2016

Researchers engineer antibodies that could potently neutralize two deadliest strains of Ebola virus

Researchers at Albert Einstein College of Medicine and the U.S. Army Medical Research Institute of Infectious Diseases have engineered the first antibodies that can potently neutralize the two deadliest strains of the virus that causes Ebola hemorrhagic fever.

13 Jan 2016

UM SOM to team up with industry to develop vaccine for preventing deadly bacterial infections

The Center for Vaccine Development at the University of Maryland School of Medicine will participate in a partnership with industry to develop a vaccine to prevent a group of deadly bacterial infections that occur commonly among hospital patients.

13 Jan 2016

Study finds communication gap between doctors and parents in management of children's food allergies

When a child has a food allergy, it's critical for pediatricians and allergists to show parents when and how to use an epinephrine auto-injector and to provide a written emergency food allergy action plan for home and school. It is essential in case of a life-threatening reaction.

13 Jan 2016

UHN's multi-disciplinary team successfully completes Canada's first transplant of the upper limb

In a Canadian first, a multi-disciplinary team, led by Dr. Steven McCabe, has successfully completed the country's first transplant of the upper limb.

13 Jan 2016

Long-term use of opioids increases risk of new-onset depression

Opioids may cause short-term improvement in mood, but long-term use imposes risk of new-onset depression, a Saint Louis University study shows.

13 Jan 2016

New gene-filtering tool aims to predict disease-causing mutations

Despite their bad reputations, the vast majority of mutations are not harmful. Even in very rare genetic disorders, only one or two genetic variations — out of tens of thousands — is actually the cause of disease. Distinguishing between harmful and harmless mutations has long been a challenge.

13 Jan 2016

Infectious Diseases News and Research

Profectus begins Phase 1 clinical study of VesiculoVax-vectored Ebola virus vaccine

Researchers suggest ways to make TB drugs more efficacious against mutations

New clinical imaging method may enable doctors to tackle lung infections

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

UGA study helps solve mystery of how African trypanosomes communicate

Gene linked to autism lays groundwork for crucial brain structure during prenatal development

Large-scale clinical trial to evaluate dengue vaccine launched in Brazil

Researchers engineer antibodies that could potently neutralize two deadliest strains of Ebola virus

UM SOM to team up with industry to develop vaccine for preventing deadly bacterial infections

Study finds communication gap between doctors and parents in management of children's food allergies

UHN's multi-disciplinary team successfully completes Canada's first transplant of the upper limb

Long-term use of opioids increases risk of new-onset depression

New gene-filtering tool aims to predict disease-causing mutations

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Genomics portfolio expanded by Illumina

Malaysian scientists join forces with Harvard experts to help revolutionize lung disease treatment

Researchers use quick screening method to identify, test promising anti-Ebola drugs

American College of Cardiology to honor LA BioMed researcher with Distinguished Teacher Award

Salk Institute scientists find new target for glioblastoma multiforme treatment

ISHLT issues new list of criteria to determine patient eligibility for heart transplant

Industry Focus: Infectious Diseases eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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