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Immune system activation is modulated according to the time of day

Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms.

18 Oct 2021

Factors contributing to a weak antibody response to the Pfizer COVID-19 vaccine

A new study discusses risk factors for the failure of seroconversion following full vaccination with the COVID-19 Pfizer vaccine.

18 Oct 2021

Study identifies the role of a key cell receptor in efferocytosis after ischemic stroke

It's clear that taking out the trash is an essential process in maintaining a clean and tidy home. But did you know that your body has a similar process for waste removal in which damaged cells are "thrown out"? A research team in Japan has recently shed new light on the dynamics of this process—termed efferocytosis—following ischemic stroke.

18 Oct 2021

Famous scientist joins NYU Langone’s Division of Rheumatology

Nationally recognized for his work studying a novel inflammatory disorder known as VEXAS, David B. Beck, MD, PhD, has joined the Division of Rheumatology at NYU Langone.

18 Oct 2021

Study uncovers neuronal circuitry that may play a key role in mediating pain-induced anhedonia

A new study published today in Nature Neuroscience has uncovered neuronal circuitry in the brain of rodents that may play an important role in mediating pain-induced anhedonia - a decrease in motivation to perform reward-driven behaviors.

18 Oct 2021

Novel combination therapy identified for the brain metastases of breast cancer

A Ludwig Cancer Research study has identified and preclinically validated combination treatments for the brain metastases of breast cancer, a common and typically lethal manifestation of the malignancy.

18 Oct 2021

Statin treatment and COVID-19 mortality

The authors highlight the importance of their study in clarifying and expanding the current understanding of the relationship between COVID-19 and statins.

18 Oct 2021

New class of CXCR4 antagonists could prevent airway inflammation and atopic dermatitis

Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist andinverse agonistof CXCR4 and is a promising compound for the development of improved analogues for the therapy of CXCR4-associated diseases.

18 Oct 2021

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

A group of researchers from the United States discovered that the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce the formation of highly inflammatory blood clots amenable to neutralization by a fibrin-targeting monoclonal antibody – opening the door for a completely new strategy to reduce thrombotic inflammation in coronavirus disease 2019 (COVID-19).

17 Oct 2021

Common treatment for MIS-C patients likely works by depleting neutrophils

Intravenous immune globulin (IVIG) — a common treatment for multisystem inflammatory syndrome in children (MIS-C) — likely works by depleting immune cells called neutrophils, according to a recent study funded by the National Institutes of Health.

15 Oct 2021

Daily use of cannabidiol oil may shrink lung tumors

It may be worth exploring further the use of cannabidiol ('CBD') oil as a potential lung cancer treatment, suggest doctors in BMJ Case Reports after dealing with a daily user whose lung tumor shrank without the aid of conventional treatment.

15 Oct 2021

Study finds menstrual bleeding changes after SARS-CoV-2 vaccination

A new study investigated menstrual bleeding patterns among current and former menstruating people, based on the premise that these bleeding changes were associated with changes in clotting or inflammation, which can affect the normal menstrual repair.

15 Oct 2021

Severe COVID-19 pneumonia patients with high ferritin show better outcomes after steroid treatment

During the entire pandemic, physicians treating patients with severe Covid-19 pneumonia continuously looked for hints and signs on what may enable patients to have better outcomes.

15 Oct 2021

Experts review progress in using photobiomodulation therapy to treat diverse brain disorders

Photobiomodulation (PBM) offers exciting opportunities for improving the life of patients with a diverse range of brain disorders.

14 Oct 2021

Research reveals 3D structure of cell receptor with critical role in health and disease

Cells communicate with their environment via receptors on their surface. When a protein approaches these receptors, they can pass along a message to the inside of the cell, for example the instruction to grow which can lead to tumor formation.

13 Oct 2021

Study shows how tissue-derived T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

13 Oct 2021

Study reveals a link between air pollution and child health

Studies have shown air pollution is a major risk factor for respiratory infection – the leading cause of death among children under five – but bad air's specific impacts on developing bodies have remained somewhat of a mystery.

13 Oct 2021

Study reveals the zoonotic potential of the rat Sialodacryoadenitis virus

A new review aimed to describe the current state of knowledge on Sialodacryoadenitis virus, along with its characteristics and potential zoonotic threat.

13 Oct 2021

Anti-rheumatic drug as a potential candidate for treating COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces inflammatory cytokine storms. But an FDA-approved anti-rheumatic drug, Auranofin, used to treat autoimmune and infectious diseases, may also help serve as an antiviral treatment for COVID-19 infection.

13 Oct 2021

New study finds SARS-CoV-2 causes retinal infection

Can coronavirus disease 2019 (COVID-19) affect the eye? New research suggests the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter the eye and infect photoreceptor and retinal ganglion cells. In addition, SARS-CoV-2 infection increases the expression of several inflammatory genes, including the cytokine interleukin 33 (IL33), which is linked to COVID-19 disease and retinal degeneration.

13 Oct 2021