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Cellular aging associated with structural changes in the brain

Telomeres are protective caps at the ends of chromosomes that become shorter with each cell division. If they become so short that the genes they protect could be damaged, the cell stops dividing and renewing.

27 Sep 2019

Exposure to air pollution during pregnancy associated with reductions in children's lung function

New research by the Centre for Environmental Health and Sustainability (CESH) at the University of Leicester indicates that exposure to air pollution from road traffic as early as the first trimester of pregnancy and in early life is associated with small but significant reductions in children's lung function at the age of eight years.

27 Sep 2019

New study on gene modulation may help prevent blindness

Genes borrowed from a spider turned Peter Parker into Spiderman. If scientists can use archaea--tiny organisms similar to bacteria--as a source of useful genes for humans, might it help prevent blindness one day?

27 Sep 2019

Testing the usability of novel mobile app designed to improve care for Alzheimer's patients

A Regenstrief Institute research scientist is testing a novel mobile app designed to improve care for people with Alzheimer's disease. Daniel Bateman, M.D., has received a career development award from the National Institute on Aging to test the feasibility and usability of the revised Brain CareNotes app.

26 Sep 2019

Pesticide exposure on the job related to more strokes, heart attacks

A new study published in the Journal of the American Heart Association, September 25, 2019, reports that the risk of cardiovascular disease (CVD) is increased by 42% in Japanese-American men exposed to high levels of pesticide. This is the first time this outcome has been explored in this group, and indicates that the role played by occupational pesticide exposure in the pathogenesis of CVD needs to be examined.

25 Sep 2019

New needle-free 'exosome' treatment to reduce wrinkles in UV-exposed mice

In the quest for a more youthful appearance, many people slather ointments on their skin or undergo injections of dermal fillers. But topical treatments often aren't very effective because they don't penetrate deep within the skin, whereas the results from injections typically last for only a few months and can be painful.

25 Sep 2019

New review provides knowledge about sex-related differences in Parkinson's disease

There is growing evidence that Parkinson's disease affects women and men differently. In this insightful review, published in the Journal of Parkinson's Disease, scientists present the most recent knowledge about these sex-related differences and highlight the significance of estrogens, which play an important role in the sex differences in PD.

25 Sep 2019

Pesticide exposure linked to increased risk of heart disease and stroke

On-the-job exposure to high levels of pesticides raised the risk of heart disease and stroke in a generally healthy group of Japanese American men in Hawaii, according to new research published in the Journal of the American Heart Association, the open access journal of the American Heart Association.

25 Sep 2019

Inflammasome, Boehringer Ingelheim team up to develop new therapies for retinal diseases

Boehringer Ingelheim and Inflammasome Therapeutics Inc. (Inflammasome) today announced they have entered into a co-development and license agreement to develop up to three therapies for patients with retinal diseases.

From Boehringer Ingelheim International GmbH 25 Sep 2019

Space-based investigation helps address challenges involved in learning more about the human brain

Researchers studying neurological diseases face several daunting challenges. For one thing, these conditions may take years or even decades to develop.

25 Sep 2019

How older adults can make life easier and safer despite declining vision

The number of older Americans with low vision is expected to double in the coming years, as more people live longer.

24 Sep 2019

Survey: Men have low levels of awareness about prostate health and function

The survey, which assessed knowledge of the prostate in 3,010 men over 50 years in the UK, Germany and France, found that just one in 4 men (26%) over the age of 50 are correctly able to identify the prostate's main function.

24 Sep 2019

Falls Prevention Awareness Day focuses on risk of osteoporosis

With more than a quarter of seniors in the U.S. falling each year, many risk breaking a brittle bone, according to the National Council on Aging, which today is marking Falls Prevention Awareness Day. And often, seniors don't realize why they are at risk.

24 Sep 2019

New method can enable POLST form to reflect informed preferences of patients, families

A team, led by Regenstrief Institute researcher Alexia Torke, M.D., is exploring if guidance in filling out medical treatment options on the POLST form makes a measurable difference in a person's care preferences being respected.

24 Sep 2019

Synthetic oral cannabinoid use found to be more common among older adults with COPD

A study published today in Drugs & Aging found that older adults in Ontario with chronic obstructive pulmonary disease were twice as likely to use prescription synthetic oral cannabinoids compared to older adults without COPD.

23 Sep 2019

QUT researchers use deep learning methods for more accurate eye testing

Queensland University of Technology researchers have applied artificial intelligence deep learning techniques to develop a more accurate and detailed method for analyzing images of the back of the eye to help clinicians better detect and track eye diseases, such as glaucoma and age-related macular degeneration.

23 Sep 2019

How one family counters epilepsy and caregiver stress by giving back

For people with epilepsy, seizures affect almost every aspect of their lives. The seizures also affect their caregivers' lives, with impacts on physical health, emotional functioning, social relationships, employment and finances.

23 Sep 2019

Researchers develop new technology to study cell nanomechanics

Researchers at Singapore-MIT Alliance for Research and Technology and MIT's Laser Biomedical Research Center have developed a new way to study cells, paving the way for a better understanding of how cancers spread and become killers.

20 Sep 2019

Targeting specific enzyme could combat Alzheimer’s disease on two fronts

UQ researchers have discovered a potential drug target for Alzheimer’s disease — an enzyme which has effects on both the immune and nervous systems.

19 Sep 2019

Protein prevalent in older people interferes with bone healing

Broken bones are a bigger deal the older you are: even after they've healed, the bones of older people are weaker and more likely to re-fracture. And since more than 6 million Americans break a bone each year, figuring out how to help people heal better would make a big difference.

19 Sep 2019