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New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

New approach could help in treating brain tumors, other rare cancers

Large randomized clinical trials can uncover biomarkers that indicate which cancer treatments are likely to work best for individual patients. But it's been challenging to find these biomarkers in rarer cancers where such robust data aren't available.

13 Jun 2019

Genetic variations linked with persistence of immunity after routine childhood vaccination

A genome-wide search in thousands of children in the UK and Netherlands has revealed genetic variants associated with differing levels of protective antibodies produced after routine childhood immunizations.

12 Jun 2019

Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Researchers from Joslin Diabetes Center, using a genome-wide association study, have identified a genetic factor linked to the development of diabetic peripheral neuropathy.

12 Jun 2019

Study emphasizes the need for personalized dietary plans, as not even twins show the same responses

Researchers have found that many widely accepted dietary guidelines are not suitable for everyone, with even twins responding differently to the same foods.

11 Jun 2019

Polygenic risk scores based on entire genome sequence may reliably predict heart disease

Specialized risk scores derived from testing that calculates the cumulative effect of an individual's entire DNA sequence, the genome, may reliably predict heart disease in people who have not yet had a heart attack, according to new research in Circulation: Genomic and Precision Medicine, an American Heart Association journal.

11 Jun 2019

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

11 Jun 2019

Researchers map the most common bacterial cause of pneumonia around the world

Researchers have mapped the most common bacterial cause of pneumonia around the world and revealed how these bacteria evolve in response to vaccination.

11 Jun 2019

Human body is a mosaic pattern of DNA mutations, say researchers

Researchers have discovered that the cells of the human body aren’t clones of a single DNA sequence, but are actually a mosaic of mutations.

7 Jun 2019

Longevity-related molecular programs do not last beyond midlife

Just as a computer requires code to work, our bodies are regulated by molecular "programs" that are written early in life and then have to do their job properly for a lifetime. But do they? It's a question that has intrigued researchers for years.

7 Jun 2019

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Princeton University researchers have discovered that learned behaviors can be inherited for multiple generations in C. elegans, transmitted from parent to progeny via eggs and sperm cells.

7 Jun 2019

Researchers one step closer to unmasking the cause of familial MS

A new study has uncovered mutations in 12 genes that may be responsible for the familial type of multiple sclerosis (MS).

7 Jun 2019

Telomere shortening in adulthood is not caused by smoking, say researchers

A new study suggests that telomere length in adults should be regarded as a static biomarker that does not significantly change during adult life.

7 Jun 2019

NIH funds clinical trials to assess applicability of genomics for treating chronic diseases

The National Institutes of Health will fund clinical trials to assess the benefits, applicability and efficacy of applying genomic medicine interventions to improve management of diseases such as high blood pressure, depression and chronic pain.

6 Jun 2019

Scientists successfully carry out gene editing in vivo

Scientists at Harvard University have successfully proven that stem cells can be edited inside the body, rather than in a petri dish.

5 Jun 2019

Promega launches MSI educational website

Researchers and clinicians seeking to deepen their understanding of Microsatellite Instability have a new resource gathering information in one place.

From Promega Corporation 4 Jun 2019

New tool reveals how genes interact to form tissues and organisms

Although the knowledge we have about human cells and tissues has steadily increased over recent decades, many things remain unknown.

4 Jun 2019

Targeting immune cells could potentially treat some kinds of brain tumor, study suggests

Tumors arise when cells shake off their restraints and start to multiply out of control. But how fast a tumor grows does not depend solely on how quickly the cancer cells can divide, a new study has found.

4 Jun 2019

Early genome catastrophes can lead to development of lung cancer in non-smokers

Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers.

31 May 2019

IDT releases new ultra-high performance CRISPR Cas12a enzyme

As an advocate for the needs of researchers working at the forefronts of genomic research, Integrated DNA Technologies releases its latest CRISPR enzyme Alt-R® Cas12a Ultra.

From Integrated DNA Technologies 31 May 2019

Genome News and Research

New technology harnesses bacterial jumping genes for precise DNA integration

New approach could help in treating brain tumors, other rare cancers

Genetic variations linked with persistence of immunity after routine childhood vaccination

Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Study emphasizes the need for personalized dietary plans, as not even twins show the same responses

Polygenic risk scores based on entire genome sequence may reliably predict heart disease

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

Researchers map the most common bacterial cause of pneumonia around the world

Human body is a mosaic pattern of DNA mutations, say researchers

Longevity-related molecular programs do not last beyond midlife

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Researchers one step closer to unmasking the cause of familial MS

Telomere shortening in adulthood is not caused by smoking, say researchers

NIH funds clinical trials to assess applicability of genomics for treating chronic diseases

Scientists successfully carry out gene editing in vivo

Promega launches MSI educational website

New tool reveals how genes interact to form tissues and organisms

Targeting immune cells could potentially treat some kinds of brain tumor, study suggests

Early genome catastrophes can lead to development of lung cancer in non-smokers

IDT releases new ultra-high performance CRISPR Cas12a enzyme

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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