Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

New imaging techniques at Mayo Clinic reveal tumor firmness, adhesion before brain cancer surgery

It's not often that a fall saves someone's life. Helen Powell, 74, says that was the case for her. A computerized tomography scan that followed her fall revealed a cancerous brain tumor that led her to Mayo Clinic and surgery using first-in-the-world technology.

4 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

Researchers uncover new mechanism that explains cause of portal hypertension

Investigators at the Medical University of South Carolina have identified a critical regulatory mechanism for the production of nitric oxide. Endothelial nitric oxide synthase is the enzyme responsible for the production of NO and its activity is tightly controlled in liver endothelial cells via a series of complex molecular mechanisms; however, in liver injury, eNOS activity, and subsequently NO production, is dysregulated.

3 May 2017

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Invivoscribe® Technologies Inc., a global company with more than 20 years of experience providing clonality and biomarker test solutions for the fields of oncology, personalized molecular diagnostics® and personalized molecular medicine®, today announces the premarket approval of LeukoStrat® CDx FLT3 Mutation Assay.

3 May 2017

Shire and Parion Sciences to collaborate on P-321 for ophthalmic indications

Shire plc and Parion Sciences, Inc. have announced they have entered into an agreement granting Shire exclusive worldwide rights to develop and commercialize P-321. Shire will lead development of P-321, an investigational epithelial sodium channel (ENaC) inhibitor for the potential treatment of dry eye disease in adults, with the opportunity for Parion to co-fund.

3 May 2017

Stereotactic radiation provides effective, noninvasive treatment option for kidney cancer patients

Kidney cancer patients may soon have an alternative to traditional treatments, new research at UT Southwestern Medical Center's Kidney Cancer Program of the Harold C. Simmons Comprehensive Cancer Center shows.

2 May 2017

Access to prostate cancer treatments in the UK

A major reason for the unmet need in prostate cancer in the UK is the length of time it takes to get new treatments through the reimbursement system with NICE (National Institute for Health and Care Excellence). This has a long-term impact on the UK, making the UK far behind the rest of Europe and even globally in terms of standard of care.

2 May 2017

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

A shorter course of radiation therapy given to breast cancer patients following mastectomy is safe and effective and cuts treatment time in half. That is according to data from a phase II clinical trial conducted by Rutgers Cancer Institute of New Jersey investigators and other colleagues who examined a hypofractionated regimen given over three weeks versus the traditional six week course of treatment.

2 May 2017

Combination therapy may be effective option for treating some women with ovarian cancer

Researchers have been trying to understand why up to 85 percent of women experience recurrence of high-grade serous ovarian cancer -- the most common subtype of ovarian cancer -- after standard treatment with the chemotherapy drug carboplatin.

2 May 2017

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

A Mayo Clinic research team has developed a new type of cancer-fighting nanoparticle aimed at shrinking breast cancer tumors, while also preventing recurrence of the disease.

2 May 2017

UH-led researchers focus on creating durable T cells to make immunotherapy more effective

Immunotherapy, in which cells from the human immune system are unleashed to fight disease, has been the big story in cancer treatment over the past few years. When it works, it can spur long-lasting remission in patients for whom other treatments have failed.

2 May 2017

Special issue of Evidence-Based Oncology focuses on benefits and challenges of APMs in cancer care

The revolution in how physicians will be paid brings unique challenges to cancer care, where individual patient needs may make costs hard to predict.

29 Apr 2017

Takeda announces accelerated approval from FDA for new lung cancer treatment

Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that ALUNBRIG (brigatinib) has received Accelerated Approval from the U.S. Food and Drug Administration for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.

28 Apr 2017

FDA approves new drug and chemotherapy combination for treatment of adult patients with AML

The U.S. Food and Drug Administration today approved Rydapt (midostaurin) for the treatment of adult patients with newly diagnosed acute myeloid leukemia who have a specific genetic mutation called FLT3, in combination with chemotherapy.

28 Apr 2017

New prognostic tool accurately predicts recurrence of parathyroid cancer

A newly-created prognostic tool reliably predicts the recurrence of parathyroid cancer, enabling physicians to identify patients at the highest risk.

28 Apr 2017

Gene critical for tumor progression also encourages growth of intestinal stem cells, study shows

A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages the growth of cells that support them, according to results of a study led by Johns Hopkins researchers.

28 Apr 2017

Stivarga receives expanded FDA approval for treatment of liver cancer

The U.S. Food and Drug Administration today expanded the approved use of Stivarga (regorafinib) to include treatment of patients with hepatocellular carcinoma (HCC or liver cancer) who have been previously treated with the drug sorafenib.

28 Apr 2017

Pairing curcumin with turmeric essential oils offers better protection from ulcerative colitis, study finds

Curcumin has been studied widely and hailed for its anti-inflammatory properties, but a new study by researchers at Baylor Scott & White Research Institute shows other compounds in turmeric – the popular spice it's derived from – hold additional health benefits.

28 Apr 2017

Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

The molecule CD103 is key to the long-term residence of T cells in the skin and to their anti-tumor function, report a team of researchers at the Medical University of South Carolina and the Dartmouth-Hitchcock Norris Cotton Cancer Center In the April 14, 2017, Science Immunology.

28 Apr 2017

Oncology News and Research

Further Reading

New imaging techniques at Mayo Clinic reveal tumor firmness, adhesion before brain cancer surgery

Scientists map genetic changes that help drive aggressive brain tumor

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Researchers uncover new mechanism that explains cause of portal hypertension

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Shire and Parion Sciences to collaborate on P-321 for ophthalmic indications

Stereotactic radiation provides effective, noninvasive treatment option for kidney cancer patients

Access to prostate cancer treatments in the UK

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

Combination therapy may be effective option for treating some women with ovarian cancer

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

UH-led researchers focus on creating durable T cells to make immunotherapy more effective

Special issue of Evidence-Based Oncology focuses on benefits and challenges of APMs in cancer care

Takeda announces accelerated approval from FDA for new lung cancer treatment

FDA approves new drug and chemotherapy combination for treatment of adult patients with AML

New prognostic tool accurately predicts recurrence of parathyroid cancer

Gene critical for tumor progression also encourages growth of intestinal stem cells, study shows

Stivarga receives expanded FDA approval for treatment of liver cancer

Pairing curcumin with turmeric essential oils offers better protection from ulcerative colitis, study finds

Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

Cancer Research - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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