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Study provides new insight into the heritability of coronary artery disease

A collaboration involving the Icahn School of Medicine at Mount Sinai, the German Heart Center Munich, AstraZeneca, and Karolinska Institutet in Sweden has demonstrated that more than 30 percent of heart disease risk stems from genetic factors, much more than was previously understood.

18 Jun 2019

Study uncovers potential modifier genes in patients with Charcot-Marie-Tooth disease

Charcot-Marie-Tooth disease is the most common inherited neurological disorder affecting peripheral motor and/or sensory nerves in humans.

18 Jun 2019

Researchers find way to reinvigorate exhausted immune cells and stop cancer

The human immune system relies on a delicate balance of finely tuned cell types that keep germs and cancerous cells in check.

18 Jun 2019

Up to 80% of metastatic colorectal cancers spread to far areas before diagnoses

Up to 80% of metastatic colorectal cancers are likely to have spread to distant locations in the body before the original tumor has exceeded the size of a poppy seed, according to a study of nearly 3,000 patients by researchers at the Stanford University School of Medicine.

18 Jun 2019

Genetic study on liver iron content may pave way for better treatment

High levels of iron in the liver are linked to a number of serious health conditions including cancer, diabetes, high blood pressure and cardiovascular as well as liver disease. But measuring liver iron is difficult and until recently could only be done through an invasive biopsy.

17 Jun 2019

Mutations in fetal genome may contribute to premature birth

Mutations in the gene that codes for SLIT2, a protein expressed in fetal cells in placentas and involved in directing the growth of the fetal nervous system, may contribute to premature births, possibly by activating the mother’s immune system.

From PLOS ONE 14 Jun 2019

Researchers find salmonella resistant to antibiotics of last resort in the U.S.

Researchers from North Carolina State University have found a gene that gives Salmonella resistance to antibiotics of last resort in a sample taken from a human patient in the U.S. The find is the first evidence that the gene mcr-3.1 has made its way into the U.S. from Asia.

13 Jun 2019

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

As part of its ongoing mission to advocate for researchers in the genomics age, Integrated DNA Technologies will unveil the latest additions to its NGS catalog to the European market at the European Human Genetics Conference in Gothenburg, Sweden on 15–18 June, 2019.

From Integrated DNA Technologies 13 Jun 2019

OGT expands SureSeq NGS portfolio with a complete library preparation solution

Oxford Gene Technology (OGT), The Molecular Genetics Company, has expanded its SureSeq portfolio with a complete library preparation solution for hybridization-based target capture in NGS, making its market-leading coverage uniformity and expertise even more accessible.

From Oxford Gene Technology 13 Jun 2019

Study: Phthalate susceptibility depends largely on genetic heritage of individual

Phthalates, one of the most common endocrine disruptors, are commonly used by industry in many plastic products - toys, clothing, baby bottles or even medical equipment - as well as in cosmetics.

13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

New approach could help in treating brain tumors, other rare cancers

Large randomized clinical trials can uncover biomarkers that indicate which cancer treatments are likely to work best for individual patients. But it's been challenging to find these biomarkers in rarer cancers where such robust data aren't available.

13 Jun 2019

Genetic variations linked with persistence of immunity after routine childhood vaccination

A genome-wide search in thousands of children in the UK and Netherlands has revealed genetic variants associated with differing levels of protective antibodies produced after routine childhood immunizations.

12 Jun 2019

Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Researchers from Joslin Diabetes Center, using a genome-wide association study, have identified a genetic factor linked to the development of diabetic peripheral neuropathy.

12 Jun 2019

Study emphasizes the need for personalized dietary plans, as not even twins show the same responses

Researchers have found that many widely accepted dietary guidelines are not suitable for everyone, with even twins responding differently to the same foods.

11 Jun 2019

Polygenic risk scores based on entire genome sequence may reliably predict heart disease

Specialized risk scores derived from testing that calculates the cumulative effect of an individual's entire DNA sequence, the genome, may reliably predict heart disease in people who have not yet had a heart attack, according to new research in Circulation: Genomic and Precision Medicine, an American Heart Association journal.

11 Jun 2019

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

11 Jun 2019

Genome News and Research

Study provides new insight into the heritability of coronary artery disease

Study uncovers potential modifier genes in patients with Charcot-Marie-Tooth disease

Researchers find way to reinvigorate exhausted immune cells and stop cancer

Up to 80% of metastatic colorectal cancers spread to far areas before diagnoses

Genetic study on liver iron content may pave way for better treatment

Mutations in fetal genome may contribute to premature birth

Researchers find salmonella resistant to antibiotics of last resort in the U.S.

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

OGT expands SureSeq NGS portfolio with a complete library preparation solution

Study: Phthalate susceptibility depends largely on genetic heritage of individual

New technology harnesses bacterial jumping genes for precise DNA integration

New approach could help in treating brain tumors, other rare cancers

Genetic variations linked with persistence of immunity after routine childhood vaccination

Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Study emphasizes the need for personalized dietary plans, as not even twins show the same responses

Polygenic risk scores based on entire genome sequence may reliably predict heart disease

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

Researchers map the most common bacterial cause of pneumonia around the world

Human body is a mosaic pattern of DNA mutations, say researchers

Longevity-related molecular programs do not last beyond midlife

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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