Clinical Trial News and Research

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Researchers create new method to ensure integrity of clinical trials data with blockchain

UC San Francisco researchers have created a proof-of-concept method for ensuring the integrity of clinical trials data with blockchain.

23 Feb 2019

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Patients with Duchenne muscular dystrophy have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

23 Feb 2019

Researchers investigate how marijuana and tobacco co-use affects quit attempts by smokers

Tobacco isn't the only thing being smoked in the Deep South, and for many, it's only half of their habit.

23 Feb 2019

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

21 Feb 2019

Thousands with chronic UTIs are not receiving the treatment they need

Many women may not be receiving the treatment they need because the gold-standard tests for UTIs fail to detect a significant proportion of bacteria.

21 Feb 2019

Scientists can monitor brain activity to predict epileptic seizures few minutes in advance

Elizabeth Delacruz can't crawl or toddle around like most youngsters nearing their second birthday.

21 Feb 2019

Some drug combinations may be more effective than others for schizophrenic patients

Patients with schizophrenia are often treated with more than one type of psychiatric medication, but a new study suggests that some combinations may be more effective than others.

21 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

BGU develops new AI platform for monitoring and predicting ALS progression

Ben-Gurion University of the Negev has developed a new artificial intelligence (AI) platform for monitoring and predicting progression of neurodegenerative diseases to help identify markers for personalized patient care and improve drug development.

20 Feb 2019

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumors in several mouse models.

20 Feb 2019

First gene therapy operation for macular degeneration is a success

A new treatment is the first to target the underlying genetic cause of AMD, which affects more than 600,000 people in the UK alone.

20 Feb 2019

Clinical trial researchers can initiate advance care planning discussions to help cancer patients

Cancer clinical trials are an important option for patients with cancer. Yet, once a trial ends, patients still need care plans.

20 Feb 2019

Study suggests new treatment strategy for deadly brain cancer

In a study of mice and human brain tumors researchers at the University of the Michigan, Ann Arbor, searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others.

19 Feb 2019

Common acid reflux drugs tied to elevated risk for kidney disease

Proton pump inhibitors, which include well-known brand names Prilosec, Nexium and Prevacid, are among the most commonly prescribed medications in the world. Approximately 10 percent of adults in the United States take these drugs for frequent heartburn, acid reflux and gastroesophageal reflux disease.

19 Feb 2019

Drug combinations could become first-line treatment for metastatic kidney cancer

A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.

18 Feb 2019

H-RT should be the standard of care for men with low risk prostate cancer, study shows

Results from the NRG Oncology clinical study NRG-RTOG 0415 determined that a hypofractionated radiotherapy schedule, a treatment schedule that delivers a total dose of radiotherapy over a shorter period of time, is not worse than the conventional radiotherapy schedule in terms of bowel, bladder, sexual, and general quality of life as well as anxiety and depression for men with low risk prostate cancer.

15 Feb 2019

New technique using patients' own modified cells could help treat Crohn's disease

A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months.

15 Feb 2019

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial led by investigators at The University of Texas MD Anderson Cancer Center presented today at the American Society of Clinical Oncology Genitourinary Cancers Symposium in San Francisco.

15 Feb 2019

WVU gynecologic oncologist investigates novel treatment for cervical and vaginal cancers

Cervical cancer can be insidious. Changes to the cervix are often detected with a pap smear, but for those with limited access to health care, cervical and vaginal cancers can go unnoticed for years--silently growing, spreading and invading other organs--and by the time they're detected, they may be so advanced that the patient's prognosis is poor and her treatment options few.

15 Feb 2019

Large-scale clinical trial begins to study liver transplantation between people with HIV

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery.

15 Feb 2019

Clinical Trial News and Research

Researchers create new method to ensure integrity of clinical trials data with blockchain

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Researchers investigate how marijuana and tobacco co-use affects quit attempts by smokers

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Thousands with chronic UTIs are not receiving the treatment they need

Scientists can monitor brain activity to predict epileptic seizures few minutes in advance

Some drug combinations may be more effective than others for schizophrenic patients

Why melanoma tumors in the brain may be worse?

BGU develops new AI platform for monitoring and predicting ALS progression

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

First gene therapy operation for macular degeneration is a success

Clinical trial researchers can initiate advance care planning discussions to help cancer patients

Study suggests new treatment strategy for deadly brain cancer

Common acid reflux drugs tied to elevated risk for kidney disease

Drug combinations could become first-line treatment for metastatic kidney cancer

H-RT should be the standard of care for men with low risk prostate cancer, study shows

New technique using patients' own modified cells could help treat Crohn's disease

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

WVU gynecologic oncologist investigates novel treatment for cervical and vaginal cancers

Large-scale clinical trial begins to study liver transplantation between people with HIV

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