Immune System News and Research

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Immunotherapeutic intervention to reduce stress prevents tumor metastases

Tel Aviv University researchers have found that the short time period around tumor removal surgery (the weeks before and after surgery) is critical for the prevention of metastases development, which develop when the body is under stress.

22 Jul 2020

Essential and in danger: Coronavirus sickens, even kills public health workers

As a veteran public health worker, Chantee Mack knew the coronavirus could kill. She already faced health challenges and didn't want to take any chances during the pandemic. So she asked — twice — for permission to work from home.

22 Jul 2020

Scientists isolate potent SARS-CoV-2 neutralizing antibodies from COVID-19 patients

Researchers at Columbia University Irving Medical Center have isolated antibodies from several COVID-19 patients that, to date, are among the most potent in neutralizing the SARS-CoV-2 virus.

22 Jul 2020

Scientists report two new cryo-EM structures of SARS-Cov-2 spike protein

Scientists report two new cryo-EM structures representing the pre- and postfusion conformations of the full-length SARS-CoV-2 spike (S) protein, an essential viral component responsible for host cell entry and the spread of infection.

22 Jul 2020

Study captures unexpected features of SARS-Cov-2 spike protein

The rod-like spike proteins on the surface of SARS CoV-2 are the tip of the spear of the COVID-19 pandemic.

22 Jul 2020

Researchers investigate the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Lab-made virus infects cells, interacts with antibodies just like SARS-CoV-2

Airborne and potentially deadly, the virus that causes COVID-19 can only be studied safely under high-level biosafety conditions.

21 Jul 2020

Autopsies reveal unexpected changes in the hearts of COVID-19 patients

A series of autopsies conducted by LSU Health New Orleans pathologists shows the damage to the hearts of COVID-19 patients is not the expected typical inflammation of the heart muscle associated with myocarditis, but rather a unique pattern of cell death in scattered individual heart muscle cells.

21 Jul 2020

Exploring how bacteria and viruses coexist inside the human gut

The adage "all things in moderation" applies not to just to food and drink, but also to the legions of bacteria inside our guts helping us digest that food and drink. It turns out the rule may also extend to the lesser understood bacteriophages, which are viruses that infect the bacteria living inside us.

21 Jul 2020

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.

21 Jul 2020

A multi-omics single cell analysis on COVID-19

Now, a new study published on the preprint server medRxiv aims to analyze the immune response over time, using multi-omics in the study of a single cell.

21 Jul 2020

A comprehensive review of COVID-19's effect on organ systems outside the lungs

In the early days of the COVID-19 pandemic, the disease was characterized by many as a flu-like respiratory infection mainly affecting the lungs.

20 Jul 2020

China's Ad5 vectored COVID-19 vaccine safe and induces immune response

A phase 2 trial of an Ad5 vectored COVID-19 vaccine candidate, conducted in China, has found that the vaccine is safe and induces an immune response, according to new research published in The Lancet.

20 Jul 2020

Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Promising early stage results from a phase 1/2 clinical trial of the UK's vaccine candidate against SARS-CoV-2 (the virus that causes COVID-19) are published today in The Lancet.

20 Jul 2020

Immunotherapy does not worsen complications for patients with both COVID-19 and cancer

Preliminary data from researchers at the University of Cincinnati Cancer Center show that immunotherapy doesn't necessarily worsen complications for patients with both COVID-19 and cancer.

20 Jul 2020

Experimental therapy slows zika replication and prevents microcephaly in mice

An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor), a protein with roles in regulating immunity, stem cell maintenance and cellular differentiation, enables the immune system to combat replication of zika virus in the organism far more effectively.

20 Jul 2020

Josep Carreras Institute's spin-off aims to develop new immuno-oncological therapeutic tools

The Josep Carreras Leukaemia Research Institute, a public centre pertaining to the Generalitat de Catalunya's (Government of Catalonia) CERCA network, has created the OneChain Immunotherapeutics spin-off, the aim of which is to develop new immuno-oncological therapeutic tools with various preclinical candidates, based on CAR-T technology for different tumors, such as cortical T-cell acute lymphoblastic leukemia (coT-ALL), a rare subtype of leukemia that mainly affects children, and which has a poor prognosis.

20 Jul 2020

How immune cells switch to attack mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign - so-called antigens - bind to the T-cell receptor on the T cell surface.

20 Jul 2020

UC Riverside scientist to shed light on worm infections that escape detection by immune systems

It's likely that billions of people are unaware they have been infected with parasitic worms. A UC Riverside scientist has won $1.8 million to try and understand why.

20 Jul 2020

Researchers determine how SARS-CoV-2 inhibits protein synthesis

Researchers from Munich and Ulm have determined how the pandemic coronavirus SARS-CoV-2 inhibits the synthesis of proteins in infected cells and shown that it effectively disarms the body's innate immune system.

19 Jul 2020