Clinical Trial News and Research

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Decolonization protocol after hospital discharge can prevent dangerous infections

Hospital patients who have methicillin-resistant Staphylococcus aureus can prevent future MRSA infections by following a standard bathing protocol after discharge, according to research results published in the February 14 issue of the New England Journal of Medicine.

15 Feb 2019

Research shows link between diet drinks and stroke risk among post-menopausal women

Among post-menopausal women, drinking multiple diet drinks daily was associated with an increase in the risk of having a stroke caused by a blocked artery, especially small arteries, according to research published inStroke,a journal of the American Heart Association.

14 Feb 2019

Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $12.5 million grant from the National Institute on Aging, part of the National Institutes of Health, for a five-year program called the U19 that consists of four multidisciplinary projects in aging biology.

14 Feb 2019

Cannabis use among adolescents linked with increased risk of depression in adulthood

While there has been a lot of focus on the role of cannabis use in psychosis, there has been less attention on whether cannabis use is associated with an increased risk of common mental health disorders, such as depression and anxiety.

13 Feb 2019

Breast cancer screening age should be lowered to 35 for those with a family history

Thousands of women who have a family history of breast cancer should be screened from the age of 35, rather than the current eligibility age of 40.

13 Feb 2019

UVA researcher to present updates on new artificial pancreas at AAAS Annual Meeting

A University of Virginia School of Medicine researcher will provide updates on a UVA-developed artificial pancreas - including early results from a nationwide clinical trial - during a presentation at the AAAS Annual Meeting.

13 Feb 2019

Antibody-based treatment could improve cure rate for blood and immune disorders

An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bone marrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at the Stanford University School of Medicine.

12 Feb 2019

Researchers discover new therapeutic target for rare, aggressive pediatric cancers

Researchers at The University of Texas MD Anderson Cancer Center have discovered that malignant rhabdoid tumors, a rare pediatric cancer without effective treatments, may be sensitive to drugs that block the cancer cell's ability to dispose of misfolded proteins.

12 Feb 2019

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.

11 Feb 2019

New cancer drug that acts as ‘Trojan horse’ shows promise in patients with various cancers

A brand new type of cancer drug that acts as a 'Trojan horse' to get inside tumor cells has shown promise in patients with six different cancer types.

11 Feb 2019

Home-based telerehab appears to be as effective as clinic-based therapy in restoring mobility

Home-based telerehabilitation is just as effective as clinic-based therapy at restoring arm function among stroke survivors, according to late-breaking science presented at the American Stroke Association's International Stroke Conference 2019, a world premier meeting dedicated to the science and treatment of cerebrovascular disease for researchers and clinicians.

11 Feb 2019

'Trojan horse' drug shows promise for untreatable cancers

A new cancer drug that uses a ‘Trojan horse’ approach to destroy cancer cells from within has shown promising results for patients with untreatable cancers.

8 Feb 2019

New clinical trial aims to examine safety and use of two HIV prevention tools

A clinical trial has begun to examine the safety and use of two HIV prevention tools--oral pre-exposure prophylaxis and a vaginal ring--in adolescent girls and young women in southern Africa.

8 Feb 2019

Pregnant women face greater risk of having hemorrhagic stroke, reveal studies

Pregnant women face a much greater risk of having a fatal, but less common, type of stroke caused by bleeding into the brain, according to results of two studies presented by The University of Texas Health Science Center at Houston at the International Stroke Conference 2019.

8 Feb 2019

New study aims to investigate lifestyle effects on cognitive function in older adults

Researchers in Finland recently found that lifestyle choices can help older adults stay mentally sharp. Now scientists at Wake Forest School of Medicine hope to find confirmatory evidence this is indeed the case by coordinating a large, national clinical trial sponsored by the Alzheimer's Association through a $28 million grant.

8 Feb 2019

Compounds found in fish oil may prevent pregnancy complications, finds study

Compounds found in fish oil prevent pregnancy complications, including preterm birth, neonatal death, and stillbirth, in mice when the complications are caused by a common oral bacteria, according to research published today in the journal JCI Insight.

8 Feb 2019

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

A multi-center phase II clinical trial investigating pembrolizumab as a first-line and programmed cell death-1 therapy in patients with advanced Merkel cell carcinoma reports lasting tumor control, generally manageable side effects and improved overall survival.

8 Feb 2019

Intensive blood pressure lowering does not improve post-stroke recovery in clot-buster-treated patients

Intensive blood pressure lowering safely reduced the risk of bleeding in the brain in ischemic stroke patients being treated with clot-busting drugs, but did not improve post-stroke recovery, according to late breaking science presented at the American Stroke Association's International Stroke Conference 2019, a world premier meeting for researchers and clinicians dedicated to the science and treatment of cerebrovascular disease.

8 Feb 2019

Creative solutions to enhance patient's point of view in neuromuscular research

The old-fashioned paternalistic relationship between doctors and patients has gradually evolved into a more collaborative one in the era of patient-centered medicine.

7 Feb 2019

New acute porphyria treatment shows promising results in clinical study

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment available for the most seriously afflicted patients.

7 Feb 2019

Clinical Trial News and Research

Decolonization protocol after hospital discharge can prevent dangerous infections

Research shows link between diet drinks and stroke risk among post-menopausal women

Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

Cannabis use among adolescents linked with increased risk of depression in adulthood

Breast cancer screening age should be lowered to 35 for those with a family history

UVA researcher to present updates on new artificial pancreas at AAAS Annual Meeting

Antibody-based treatment could improve cure rate for blood and immune disorders

Researchers discover new therapeutic target for rare, aggressive pediatric cancers

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

New cancer drug that acts as ‘Trojan horse’ shows promise in patients with various cancers

Home-based telerehab appears to be as effective as clinic-based therapy in restoring mobility

'Trojan horse' drug shows promise for untreatable cancers

New clinical trial aims to examine safety and use of two HIV prevention tools

Pregnant women face greater risk of having hemorrhagic stroke, reveal studies

New study aims to investigate lifestyle effects on cognitive function in older adults

Compounds found in fish oil may prevent pregnancy complications, finds study

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

Intensive blood pressure lowering does not improve post-stroke recovery in clot-buster-treated patients

Creative solutions to enhance patient's point of view in neuromuscular research

New acute porphyria treatment shows promising results in clinical study

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