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UQ-led project uses 'brain in a dish' to study effects of the Zika virus

A University of Queensland-led project has used a 'brain in a dish' to study the effects of the Zika virus, taking research a step closer towards developing drugs to combat the infection.

12 Dec 2022

Study provides new insights for the future development of oral insulin pill

WEHI researchers in Melbourne have answered a 100-year-old question in diabetes research: can a molecule different to insulin have the same effect? The findings provide important insights for the future development of an oral insulin pill.

12 Dec 2022

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A patient with relapsed T cell leukemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

12 Dec 2022

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Researchers developed a screening platform and identified molecules with anti-CoV activity.

12 Dec 2022

KHN investigation: The system feds rely on to stop repeat health fraud is broken

The federal system meant to stop health care business owners and executives from repeatedly bilking government health programs fails to do so, a KHN investigation has found.

12 Dec 2022

What is the incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir?

Researchers evaluated the incidence of COVID-19 rebound among SARS-CoV-2 -positive patients treated with oral antiviral drugs such as nirmatrelvir-ritonavir combination and molnupiravir.

12 Dec 2022

SARS-CoV-1 and SARS-CoV-2 spike proteins utilize different mechanisms to bind to ACE2

Researchers apply computational approaches to study the binding mechanisms of the SARS-CoV-2 and SARS-CoV spike proteins to the ACE2 receptor.

11 Dec 2022

Structural studies pave the way for cancer drugs that could target only mutated versions

To design drugs that stall the growth of aggressive cancers, it helps to know the structures of the proteins that are revving the cancers' engines.

9 Dec 2022

An epigenetic modification improves the defense against infections, research shows

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens.

9 Dec 2022

Researchers design novel compounds with potential as drug treatments for COVID-19

The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has been devastating the entire world. While the vaccination program is advancing, drug treatments for COVID-19 are still highly important for those who become infected.

9 Dec 2022

Johns Hopkins researchers characterize a broad range of psychedelic occasioned belief changes

Johns Hopkins Medicine researchers continue their exploration into psychedelics and how these drugs may produce a wide range of profound changes in perception, cognition and mood.

9 Dec 2022

Scientists trace how livestock systems act as a reservoir for antimicrobial-resistant bacteria

Scientists from the International Livestock Research Institute (ILRI), the University of Liverpool, the University of Edinburgh and elsewhere have traced how livestock systems act as a reservoir for antimicrobial-resistant (AMR) bacteria and AMR genetic determinants that may infect or colonize people.

9 Dec 2022

Study proposes a new concept for treating COVID-19 associated weight loss

Losing too much weight when infected with COVID-19 has been linked to worse outcomes. Now, researchers at Karolinska Institutet in Sweden have discovered that SARS-CoV-2 infection fuels blood vessel formation in fat tissues, thus revving up the body's thermogenic metabolism.

9 Dec 2022

What is the association between farnesoid X receptor inhibition and protection against COVID-19?

Researchers assessed the association between farnesoid X receptor (FXR) inhibition and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

9 Dec 2022

Landmark study challenges a 70-year-old theory of protein folding

A landmark study by researchers at the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University reveals how a tiny cellular machine called TRiC directs the folding of tubulin, a human protein that is the building block of microtubules that serve as the cell’s scaffolding and transport system.

9 Dec 2022

Discovery of cellular uptake pathway for larger molecules can be harnessed to create new drugs

A fundamental challenge in drug development is the balance between optimizing a drug's lock-and-key fit with its target and the drug's ability to make its way across the cellular membrane and access that target.

8 Dec 2022

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma – a lethal form of salivary gland cancer that currently has no treatment options.

8 Dec 2022

For patients with sickle cell disease, fertility care is about reproductive justice

Teonna Woolford has always wanted six kids. Why six? "I don't know where that number came from. I just felt like four wasn't enough," said Woolford, a Baltimore resident. "Six is a good number."

8 Dec 2022

Discovery of ’raspberry-shaped’ nanoparticle offers a way to enhance the effectiveness of existing drugs

A newly discovered technique, reported in the journal Nanoscale, offers a low-cost way to enhance the effectiveness of existing drugs.

7 Dec 2022

New 'heart attack on a chip' could serve as a testbed to develop personalized medicines

Researchers at the University of Southern California Alfred E. Mann Department of Biomedical Engineering have developed a "heart attack on a chip," a device that could one day serve as a testbed to develop new heart drugs and even personalized medicines.

7 Dec 2022

Drugs News and Research

UQ-led project uses 'brain in a dish' to study effects of the Zika virus

Study provides new insights for the future development of oral insulin pill

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

KHN investigation: The system feds rely on to stop repeat health fraud is broken

What is the incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir?

SARS-CoV-1 and SARS-CoV-2 spike proteins utilize different mechanisms to bind to ACE2

Structural studies pave the way for cancer drugs that could target only mutated versions

An epigenetic modification improves the defense against infections, research shows

Researchers design novel compounds with potential as drug treatments for COVID-19

Johns Hopkins researchers characterize a broad range of psychedelic occasioned belief changes

Scientists trace how livestock systems act as a reservoir for antimicrobial-resistant bacteria

Study proposes a new concept for treating COVID-19 associated weight loss

What is the association between farnesoid X receptor inhibition and protection against COVID-19?

Landmark study challenges a 70-year-old theory of protein folding

Discovery of cellular uptake pathway for larger molecules can be harnessed to create new drugs

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

For patients with sickle cell disease, fertility care is about reproductive justice

Discovery of ’raspberry-shaped’ nanoparticle offers a way to enhance the effectiveness of existing drugs

New 'heart attack on a chip' could serve as a testbed to develop personalized medicines

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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