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Diabetes drug metformin alters blood metal levels in humans

The widely used diabetes drug metformin changes blood metal levels in humans. The Kobe University study is an important step in understanding the drug's many actions and designing better ones in the future.

1 Sep 2025

Metals and sulfate particles drive asthma hospitalizations linked to air pollution

Metals, particularly nickel and vanadium, and sulfate particles are the components of fine particulate air pollution (PM2.5) that most strongly contribute to the association between long-term exposure to air pollution and hospitalization among asthma sufferers, according to a new study led by Harvard T.H. Chan School of Public Health.

29 Aug 2025

New reaction approach expands possibilities for drug discovery building blocks

A new approach to an established reaction boosts the ability to synthesize vinylic ethers - key building blocks for many molecules important to human health.

28 Aug 2025

Why Salmonella Dublin poses a food safety threat in beef and dairy

The study on Salmonella Dublin highlights its genomic similarities and resistance traits, raising concerns for food safety and antimicrobial resistance.

27 Aug 2025

Indole chemistry breakthrough opens doors for more effective drug synthesis

Indole, a molecule made up of a six-membered benzene ring fused to a five-membered ring containing nitrogen, forms the core structure of many biologically active compounds.

25 Aug 2025

ATOX1 drives hepatocellular carcinoma progression through c-Myb and PI3K/AKT activation

Despite advancements in diagnostic and therapeutic strategies, hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality.

22 Aug 2025

Why zinc may be the missing nutrient in childhood asthma care

The role of zinc in childhood asthma is critical; deficiency may worsen symptoms, while supplementation could provide a safe, effective treatment alternative.

19 Aug 2025

KAIST develops platform for electrically-controlled cell signaling

Cells use various signaling molecules to regulate the nervous, immune, and vascular systems. Among these, nitric oxide (NO) and ammonia (NH₃) play important roles, but their chemical instability and gaseous nature make them difficult to generate or control externally.

13 Aug 2025

Balancing copper antimicrobials to combat antibiotic resistance

Copper has emerged as an ally in the battle against antibiotic-resistant bacteria. Copper sulfate liquids, for example, have been used since the 1700s to control fungal infections in vineyards, orchards and many other kinds of agricultural settings.

8 Aug 2025

Scientists link brain lithium loss to early Alzheimer’s changes

Researchers have discovered that naturally occurring lithium in the brain is depleted early in Alzheimer’s disease, especially in the prefrontal cortex, and that restoring physiological levels with lithium orotate in mice can prevent brain damage and memory loss. The findings suggest lithium deficiency may be a modifiable risk factor for Alzheimer’s.

7 Aug 2025

Copper oxide scaffolds show promise in treating traumatic brain injury

Traumatic brain injury (TBI) remains one of the leading causes of disability worldwide. Recent research has developed a novel electrospun scaffold loaded with copper oxide (CuO@PG), which aims to restore copper homeostasis and modulate inflammation in TBI.

7 Aug 2025

Copper may protect brain health after stroke

Research shows dietary copper intake boosts cognitive function in older adults, particularly those with a stroke history, highlighting its neuroprotective role.

1 Aug 2025

Patients face vitamin deficiencies years after bariatric surgery

A review reveals dangerous vitamin deficiencies post-bariatric surgery, highlighting the need for improved follow-up to prevent life-threatening complications.

30 Jul 2025

Fad diets and supplements fuel new wave of hidden skin problems, study finds

A new review explains how fad diets and unregulated supplements promoted online can cause serious skin, hair, and nail problems, often before other symptoms appear. Clinicians are urged to recognize these risks and address health misinformation in the digital age.

22 Jul 2025

Cuproptosis offers new hope for treating inflammatory bowel disease and colorectal cancer

Cuproptosis represents a novel mechanism of cell death characterized by intracellular copper ion accumulation.

18 Jul 2025

Cricket flour pasta offers a safe, sustainable protein alternative

A 10% cricket flour blend in pasta enhances protein and minerals, offering a sustainable solution to malnutrition without compromising safety or flavor.

11 Jul 2025

Hydrogels could be key to safer, smarter cancer drug delivery

Hydrogels could revolutionize cancer treatment by facilitating targeted drug delivery, reducing adverse effects, and enhancing therapeutic effectiveness.

11 Jul 2025

How hydrogels are shaping the future of targeted cancer drug delivery

A large-scale bibliometric analysis maps global research on hydrogels as next-generation drug delivery systems for cancer therapy. The study highlights emerging trends, key contributors, and future directions to advance precision medicine in oncology.

10 Jul 2025

Pasta gets a protein upgrade with eco-friendly cricket flour

Cricket flour is rich in protein, essential minerals, and healthy fats, offering a sustainable boost to the nutritional quality of wheat pasta. Adding just 10% cricket flour to pasta significantly improves nutrient content and meets daily amino acid requirements while ensuring food safety.

10 Jul 2025

Can dietary copper help protect against dementia and memory loss?

Higher dietary copper intake was linked to better cognitive performance in older US adults, with benefits plateauing above a certain threshold. The effect was especially notable in stroke survivors, but further research is needed to confirm causality.

8 Jul 2025