Dyslipidemia News and Research

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Dyslipidemia is a disruption in the amount of lipids in the blood.

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Lifestyle and stress erode heart health advantage in long-term US immigrants

Foreign born immigrants to the United States have a lower risk of cardiovascular disease than their U.S.-born counterparts; however, that advantage diminishes the longer they live in the U.S., according to a study presented at the American College of Cardiology's Middle East 2025 Together with 16th Emirates Cardiac Society Conference taking place October 3-5, 2025, in Dubai, UAE.

3 Oct 2025

Cannabidiol shows promise for obesity and metabolic syndrome

Cannabidiol (CBD) shows promise in regulating appetite, glucose and lipid metabolism, and inflammation in preclinical models of obesity and metabolic syndrome. However, human evidence is still limited, highlighting the need for rigorous trials before clinical use.

29 Sep 2025

Daily walnut snacks fail to lower inflammation in adults

Research on daily walnut intake showed no significant effects on inflammatory markers or antioxidant capacity in middle-aged individuals with metabolic risks.

26 Sep 2025

New recommendations aim to identify children with familial hypercholesterolemia

The Family Heart Foundation, a leading research and advocacy organization, announced the online publication of recommendations from a multidisciplinary panel in the Journal of Pediatrics to promote the early identification of children living with familial hypercholesterolemia (FH).

23 Sep 2025

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

In a phase 3 trial, once-daily oral orforglipron induced significant, dose-dependent weight loss over 72 weeks in adults with obesity but no diabetes. It also improved multiple cardiometabolic markers with a safety profile similar to other GLP-1 receptor agonists.

18 Sep 2025

Fitness study shows exercise at work can cut chronic disease risks

Researchers evaluate the efficacy of this exercise-based workplace health promotion program at the University of L’Aqulia.

11 Sep 2025

FAU experts recommend high-potency statins to reduce LDL cholesterol

There is broad consensus that the overall body of evidence shows lowering LDL (low-density lipoprotein) cholesterol provides both statistically significant and clinically meaningful benefits in treating and preventing cardiovascular disease.

31 Jul 2025

Cardiologists urged to prioritize potent statins in managing LDL cholesterol

28 Jul 2025

Extreme childhood obesity drives liver and diabetes risks

Extreme obesity in US youth has risen significantly, linked to higher rates of diabetes and liver complications, necessitating immediate public health action.

22 Jul 2025

Date vinegar lowers blood sugar and cholesterol in type 2 diabetes

This study reveals that red date vinegar intake improves blood glucose and lipid profiles in type 2 diabetes, indicating potential for metabolic risk reduction.

22 Jul 2025

Parental cholesterol predicts asthma severity in children

Parental metabolic health influences childhood asthma severity, with paternal cholesterol showing modest protective effects against exacerbating symptoms.

18 Jul 2025

Is fruit juice good or bad for diabetes? New research reveals a genetic twist

Japanese adults with a high genetic risk for type 2 diabetes who consumed 100% fruit juice at least once per week had significantly lower odds of developing the disease. The inverse association was not seen in people with low or moderate genetic risk, highlighting gene-diet interactions.

13 Jul 2025

Ultra-processed foods threaten brain health in kids and teens, review warns

Children, adolescents, and unborn babies exposed to high levels of ultra-processed foods (UPFs) face increased risks of impaired brain development, cognitive deficits, and long-term mental health challenges. The review underscores how UPF-driven changes in reward pathways, nutrient deficits, inflammation, and the gut–brain axis can have lasting impacts across generations.

13 Jul 2025

Cagrilintide and semaglutide together drive record weight loss in global trial

A 68-week phase 3 trial found that coadministered cagrilintide and semaglutide led to significant and clinically meaningful weight loss in adults with obesity but no diabetes. The combination outperformed either drug alone and improved multiple cardiometabolic health markers.

23 Jun 2025

How early-life factors raise lifelong diabetes risks in youth

The surge in diabetes among young people highlights critical gaps in care and the urgent need for comprehensive preventative actions to address this crisis.

19 Jun 2025

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS.

5 Jun 2025

Plant-based portfolio diet linked to fewer heart-related deaths

The portfolio diet significantly lowers heart disease risk, with long-term benefits for cardiovascular health and all-cause mortality in diverse populations.

3 Jun 2025

Choosing better carbs in low-carb diets boosts health outcomes

A long-term study of the Framingham Heart Study Offspring cohort found that low-carbohydrate diets emphasizing high-quality carbs, like whole grains, fruits, and vegetables, were linked to reduced inflammation and oxidative stress. Diets low in carbohydrate quality offered no such benefits.

29 May 2025

Immune microRNAs drive new frontiers in cardiovascular disease research

Cardiovascular diseases (CVDs) continue to dominate global mortality statistics, with immune dysregulation emerging as a central feature in their pathogenesis.

28 May 2025