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Targeting brain neurons to successfully treat type 2 diabetes

Successfully treating type 2 diabetes may involve focusing on brain neurons, rather than simply concentrating on obesity or insulin resistance, according to a study published today in the Journal of Clinical Investigation.

15 May 2025

Study reveals potential new strategy to prevent or slow progression of Type 1 diabetes

A study co-led by Indiana University School of Medicine researchers presents a potential new strategy to prevent or slow the progression of Type 1 diabetes by targeting an inflammation-related protein known to drive the disease.

7 May 2025

Largest study to date reveals high blood sugar accelerates heart damage in healthy youth

In the present study, 1,595 adolescents drawn from the University of Bristol's Children of the 90s cohort were followed up from age 17 until 24 years. To assess the prevalence of prediabetes, which refers to high fasting blood glucose levels, two alternative cutpoints were used, a stricter cutpoint of ≥5.6 mmol/L recommended by the American Diabetes Association, and ≥6.1 mmol/L , which is the present recommendation in many countries.

29 Apr 2025

Metabolic syndrome in midlife linked to higher dementia risk

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of young-onset dementia, according to a study published on April 23, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

23 Apr 2025

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

Researchers identified 502 blood metabolites linked to prediabetes and type 2 diabetes, with 143 tied to the gut microbiome. The study shows how lifestyle interventions like diet and exercise can modify metabolomic profiles to support glucose control.

9 Apr 2025

New trial shows oral semaglutide reduces cardiovascular events in diabetes patients

Both the injectable and oral forms of semaglutide, a glucagon-like peptide-1 receptor agonist, have gained recent attention for their effectiveness against weight gain, high blood sugar, and even alcohol cravings.

31 Mar 2025

Older Americans support insurance coverage for obesity medications

A large majority of older Americans feel that health insurance – including Medicare – should cover anti-obesity medications, according to a new University of Michigan study.

27 Mar 2025

What do Blue Zone diets have in common? Polyphenols that may slow aging

Scientists reviewed how polyphenol-rich diets in Blue Zones may help people live longer, healthier lives by targeting biological hallmarks of aging. They call for more research to measure polyphenol intake and test its effects on human longevity.

24 Mar 2025

Could a little spice in your diet prevent gestational diabetes?

Eating chili once a month during pregnancy is linked to a significantly lower risk of gestational diabetes, while dried beans and bean soup showed no clear association.

17 Mar 2025

Novel strategy targets beta cell dysfunction in type 2 diabetes

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).

4 Mar 2025

Scientists develop fenugreek-based nanoparticles to enhance diabetes drug effectiveness

Researchers explored L-arginine-loaded lipid nanoparticles from fenugreek seed oil, finding they enhance drug stability and bioavailability, showing promise for diabetes treatment.

2 Mar 2025

New low-cost tool could revolutionize type 2 diabetes treatment

Millions of people with type 2 diabetes could receive better treatment thanks to a new, simple low-cost tool, according to groundbreaking research announced today at the Diabetes UK Professional Conference 2025 and published in the Lancet.

26 Feb 2025

Culturally relevant interventions crucial for addressing Type 2 diabetes in Indigenous youth

Culturally appropriate programs that build on the strengths and knowledge of Indigenous communities are crucial for reducing the burden of Type 2 diabetes among young people, a University of Queensland study has found.

25 Feb 2025

Inflammation and metabolic syndrome contribute to prostate enlargement in aging men

A new research paper was published by Aging (Aging-US) on January 6, 2025, in Volume 17, Issue 1, titled "The profile of oxidative stress markers (arachidonic and linoleic acid derivatives) in patients with benign prostatic hyperplasia in relation to metabolic syndrome."

19 Feb 2025

Diabetes fuels antibiotic resistance, worsening infections and treatment challenges

A new study reveals that diabetes significantly accelerates the emergence and spread of antibiotic-resistant Staphylococcus aureus infections, highlighting a major public health concern.

17 Feb 2025

Study shows how physical activity can enhance brain function and prevent dementia

A study led by scientists at Rutgers University-New Brunswick has shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain function.

23 Jan 2025

AI-based tool identifies subtypes of Type 2 diabetes using glucose monitors

Diabetes has long been lumped into two categories - Type 1, which often appears in childhood, or Type 2, which is associated with obesity and typically develops later in life. But scientists have learned that not all patients with Type 2 diabetes are the same, with some patients varying in body weight, age of onset and other characteristics.

7 Jan 2025