Inflammaging News and Research

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The aging human brain

Researchers describe alterations at the molecular and cellular levels that underly brain aging in otherwise healthy elderly adults.

3 Aug 2022

Recipients of the first ever EFP Innovation Award for Digital Solutions for Gum Health announced

The European Federation of Periodontology has announced the recipients of the first ever EFP Innovation Award for Digital Solutions for Gum Health supported by GSK.

21 Jun 2022

Fecal microbiota transplant can reverse hallmarks of aging in mice

In the search for eternal youth, poo transplants may seem like an unlikely way to reverse the aging process.

5 May 2022

mRNA vaccination induces strong humoral immune responses against SARS-CoV-2 in over 80's

A recent study assesses the serological and cellular responses to Pfizer’s BNT162b2 mRNA vaccine in people aged 80-96 years.

4 Oct 2021

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

A new study discusses the vaccination response in elderly who were vaccinated with one dose of the Pfizer vaccine 15 months after contracting COVID-19.

16 Sep 2021

Researchers explore whether cocoa supplementation can reduce aging

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

A new study shows that depleting mouse blood of the protein ADORA2B led to faster declines in memory, and increased brain inflammation.

18 Jun 2021

Chronic inflammation causes aging of the pituitary gland

Stem cell biologist Hugo Vankelecom (KU Leuven) and his colleagues have discovered that the pituitary gland in mice ages as the result of an age-related form of chronic inflammation. It may be possible to slow down this process or even partially repair it. The researchers have published their findings in PNAS.

15 Jun 2021

Researchers call for trials of rapamycin to treat COVID-19

Researchers in the United States, China, and the UK have called for immediate large-scale clinical trials of an antibiotic called rapamycin as a prophylactic and treatment approach to coronavirus disease 2019 (COVID-19) in older individuals.

4 Feb 2021

Insight into role of aging in response to SARS-CoV-2 infection

Researchers at the University of California, Irvine set out to determine the differences between young people and older adults regarding their host responses against SARS-CoV-2. The team revealed that independent of disease severity, COVID-19 was linked to a significant shift in plasma inflammatory factors. The research is posted to the pre-print server medRxiv*.

3 Feb 2021

Higher BMI linked to increased risk of SARS-CoV-2 infection

Researchers at the University of Miami Miller School of Medicine, USA, revealed that the spike-specific immunoglobulin G antibodies in obese people are negatively associated with body mass index (BMI) and serum levels of proinflammatory and metabolic markers of pulmonary inflammation.

24 Dec 2020

Immunonutrition may improve COVID-19 patients' recovery

Researchers duo Emma Derbyshire and Joanne Delange from the Nutritional Insight, Surrey, United Kingdom, explore the role of immunonutrition – nutrition that boosts or influences the immune system for those over 65 years of age in COVID-19. Their study titled, “COVID-19: is there a role for immunonutrition, particularly in the over 65s?,” was released in the latest issue of the BMJ Nutrition, Prevention and Health.

26 Nov 2020

NAM announces winners of the inaugural round of Healthy Longevity Catalyst Awards

The National Academy of Medicine, together with seven global collaborators representing nearly 50 countries and territories, today announced the winners of the inaugural round of Healthy Longevity Catalyst Awards.

16 Oct 2020

Scientists shed new light on gene regulatory pathways activated by stress hormone

Scientists have long known that chronic stress experienced early in life, or even chronic prenatal exposure to maternal stress hormones in the womb, can shorten lifespan and contribute to age-related chronic diseases like arthritis, asthma, cancer, cardiovascular disease, diabetes and even mental illness later in life -- long after the source of stress has been removed.

9 Sep 2020

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Now, a new study published on the preprint server medRxiv in July 2020 discusses the explanation in terms of the biological aging markers in patients with severe disease, rather than the chronological age.

13 Jul 2020

Gladstone scientists gain new insights into the aging brain

The protein klotho has been shown to promote longevity and counteract aging-related impairments. Having more klotho seems to allow for longer and healthier lives, whereas a depletion of this molecule accelerates aging and may contribute to age-related diseases.

12 Nov 2018

Elevated levels of inflammation marker linked to lower muscle mass

Elevated levels of the inflammation marker CRP in the blood is an underlying cause of the loss of muscle mass in elderly persons, as shown by a new study from örebro University and University of Nottingham.

11 Jan 2018

New study shows link between gut bacteria and age-related chronic inflammation

A new study shows for the first time that gut bacteria from old mice induce age-related chronic inflammation when transplanted into young mice.

3 Nov 2017

Nutrition-related strategies may modify inflammation of aging, report reveals

Aging is characterized by increased levels of inflammatory markers in the bloodstream, a phenomenon that has been termed "inflammaging". This type of enhanced inflammation tone, also designated as low grade inflammation, is associated with age-related decline of many functional systems and with increased risk of sickness, poor well-being and mortality.

6 Oct 2017

Study explores how our intestinal tract changes as we age

Scientists and clinicians on the Norwich Research Park have carried out the first detailed study of how our intestinal tract changes as we age, and how this determines our overall health.

22 May 2015