International Classification of Diseases News and Research

RSS

Scientists use blood chemistry to predict disease years before it strikes

Researchers built the largest plasma metabolome-phenome atlas using 274,241 UK Biobank participants, linking over 73,000 metabolite-trait and 52,000 metabolite-disease associations. The study shows metabolic risk scores can predict diseases years before diagnosis, with strong accuracy for diabetes and kidney complications.

22 Sep 2025

Hyperemesis gravidarum associated with increased neuropsychiatric disorders in pregnancy

The largest study on pregnant women with excessive nausea and vomiting (hyperemesis gravidarum) has identified increased risks of numerous neuropsychiatric and mental health outcomes.

18 Sep 2025

AI model maps lifetime disease risks to transform future healthcare planning

Researchers developed Delphi-2M, a transformer-based AI trained on UK Biobank and Danish health data to predict and simulate lifetime trajectories for 1,256 diseases. It accurately forecasted long-term multimorbidity risks, generated synthetic health records, and highlighted comorbidity patterns while exposing key biases.

18 Sep 2025

New diagnostic code brings recognition and support for Gulf War Illness

Gulf War illness (GWI), the chronic, debilitating condition linked to military service in the 1990-1991 Gulf War, will receive a dedicated diagnostic code in the October 2025 release of the International Classification of Diseases (ICD-10-CM).

11 Sep 2025

Planetary health diet links to longer life and lower emissions

Greater adherence to the Planetary Health Diet was linked to lower all-cause, cancer, and respiratory mortality across large US and UK cohorts, supported by a meta-analysis of 37 studies. Diets higher in PHD foods also had smaller greenhouse gas footprints, reinforcing health and environmental benefits.

9 Sep 2025

Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis

Study maps clinical, genetic, and proteomic links between gut-brain disorders and neurodegeneration, showing how diabetes, vitamin D deficiency, and bowel disorders forecast Alzheimer’s and Parkinson’s years in advance. Multimodal models in biobanks highlight early detection and personalized prevention opportunities.

28 Aug 2025

Advanced form of AI opens door to personalized cancer care

What if a computer could read a patient's medical notes and help doctors determine important information for their treatment?

1 Aug 2025

Allergies linked to lower lung cancer risk, new study finds

A meta-analysis of nearly 3.9 million participants shows people with allergies have significantly lower odds of developing lung cancer. Allergic rhinitis is particularly protective, while eczema’s effect appears limited to men.

20 Jul 2025

Shingles and RSV vaccines with AS01 adjuvant reduce dementia risk

Researchers found that older adults who received AS01-adjuvanted shingles or RSV vaccines had a significantly lower risk of developing dementia within 18 months compared to flu vaccine recipients. The protective effect is likely linked to the AS01 adjuvant itself, highlighting new avenues for dementia prevention.

30 Jun 2025

America slashes heart attack deaths but faces surge in deadly heart failure and arrhythmias

U.S. heart disease mortality has dropped 66% since 1970, mainly due to fewer ischemic heart disease deaths. However, deaths from heart failure, arrhythmias, and hypertensive heart disease have risen sharply, signaling a new public health challenge.

26 Jun 2025

Large cohort study reassures on mRNA vaccine safety for early pregnancies

A large prospective cohort study in Germany found no statistically significant increase in major birth defects following first trimester mRNA COVID-19 vaccination. While slightly higher rates of some anomalies were observed in vaccinated pregnancies, no consistent patterns or causal links emerged.

11 Jun 2025

Can scientists predict life longevity from a drop of blood?

This study presents an intrinsic capacity clock, using blood samples to predict mortality risk and enhance understanding of aging and lifestyle impacts.

8 Jun 2025

New biological age clock estimates how well someone is aging

A team of international researchers has developed a new biological age "clock" that estimates how well someone is aging, not just how "old" they or their various organs might be.

5 Jun 2025

Sleep disorders predict dementia risk years before diagnosis, study shows

Researchers analyzed health records from over 1 million people in Finland, Wales, and the UK to assess the long-term impact of sleep disorders on neurodegenerative diseases. They found that diagnosed sleep disorders can predict Alzheimer’s, Parkinson’s, and dementia risk up to 15 years before symptoms, regardless of genetic predisposition.

28 May 2025

How 196,000 Spanish participants are helping decode heart disease risk

The CORDELIA study combines data from 35 Spanish cohorts (n = 196,632) to investigate genetic, clinical, and lifestyle risk factors for ASCVD in Southern Europe. It aims to conduct the region’s most comprehensive genome-wide association study and develop tailored risk prediction tools.

14 May 2025

EAT-Lancet planetary diet shows no dementia risk, may protect against Alzheimer’s

In a large Swedish study, researchers found that the environmentally sustainable EAT-Lancet diet does not increase dementia risk and may lower the risk of Alzheimer’s and all-cause dementia, particularly in people without the APOE ε4 gene. The findings support the integration of sustainable diets into dementia prevention strategies.

15 Apr 2025

Short on time? Weekend workouts still boost longevity, researchers say

A large UK Biobank study found that concentrating weekly physical activity into one or two days provides similar mortality benefits as spreading it across the week. Regular and “weekend warrior” exercise patterns both significantly reduced all-cause, cancer, and cardiovascular mortality.

3 Apr 2025

Congenital heart defects may be linked to increased cancer risk in babies and mothers

Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published today in the American Heart Association's flagship journal Circulation.

17 Mar 2025

Researchers uncover 195 genetic risk factors driving women’s reproductive diseases

Scientists identified 195 genetic risk loci across 42 female reproductive health conditions, revealing shared genetic pathways and developing a polygenic risk score for intrahepatic cholestasis of pregnancy (ICP). These findings pave the way for personalized reproductive healthcare and targeted treatments based on genetic risk.

12 Mar 2025

Tirzepatide helps people without diabetes lose 13% body weight in real-world study

A real-world study of over 4,000 US patients without type 2 diabetes found that those who persisted with Tirzepatide for at least six months lost an average of 12.9% of their body weight. The study highlights Tirzepatide’s potential as an effective off-label obesity treatment before its formal FDA approval for weight loss.

11 Mar 2025