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Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published today in Radiology, a journal of the Radiological Society of North America.

9 Sep 2025

Dementia risk rises sharply with multiple psychiatric disorders

The odds of developing dementia are strongly linked to the number of co-existing mental health disorders, rising from twice as high for one disorder to 11 times as high for four or more, finds research published in the open access journal BMJ Mental Health.

9 Sep 2025

Blood-based biomarkers reveal barriers to diversity in Alzheimer’s disease trials

Some of the populations with the highest risk for Alzheimer's disease remain greatly underrepresented in clinical trials-and a new study helps explain why.

5 Sep 2025

KRISS develops ultra-sensitive platform to detect Alzheimer’s biomarkers in body fluids

The Korea Research Institute of Standards and Science (KRISS, President Lee Ho Seong) has developed a diagnostic platform that amplifies the unique optical signals of molecules by more than a hundred million times, enabling the precise detection and quantification of trace amounts of Alzheimer's disease biomarkers in body fluids.

1 Sep 2025

New project uses advanced PET imaging to investigate long COVID mechanisms

Using total-body PET imaging to get a better understanding of long COVID disease is the goal of a new project at the University of California, Davis, in collaboration with UC San Francisco.

29 Aug 2025

Research uncovers key role of the brain's blood flow dynamics in Alzheimer’s disease

Over seven million Americans are living with Alzheimer's disease (AD) and the heartbreaking day-to-day battle with the effects of cognitive decline.

25 Aug 2025

New 'dual-mode' tracer agent enhances precision in prostate cancer procedures

A preclinical evaluation of a new 'dual-mode' tracer agent shows promise in not only helping surgeons image and plan prostate cancer procedures, but also provide them with much more consistent and targeted guidance during surgery.

21 Aug 2025

New imaging technique enhances monitoring of atherosclerosis progression

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have shown that 18FDG-PET, an imaging technique widely used to study other conditions, can also be used to monitor atherosclerosis by measuring cellular metabolism within arterial plaques.

13 Aug 2025

AI technology advances early detection of glioblastoma progression

University of Virginia School of Medicine scientists are tapping the power of artificial intelligence to enhance and accelerate treatment for glioblastoma, the deadliest brain cancer.

7 Aug 2025

Intranasal insulin safely and effectively reaches key memory regions of the brain

A groundbreaking brain imaging study from Wake Forest University School of Medicine confirms a vital step toward new Alzheimer's disease treatments: Intranasal insulin, delivered via a simple nasal spray, safely and effectively reaches key memory regions of the brain in older adults.

23 Jul 2025

New AI tool helps clinicians identify brain activity patterns linked to nine types of dementia

Mayo Clinic researchers have developed a new artificial intelligence (AI) tool that helps clinicians identify brain activity patterns linked to nine types of dementia, including Alzheimer's disease, using a single, widely available scan - a transformative advance in early, accurate diagnosis.

3 Jul 2025

New AI tool helps clinicians identify brain activity patterns linked to nine types of dementia

30 Jun 2025

New PET radiotracer offers clearer view of brain inflammation

A newly developed PET radiotracer has shown the ability to produce high-quality images of real-time brain inflammation, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

24 Jun 2025

Indiana University researcher helps develop FDA-approved Alzheimer’s test

A first-of-its-kind blood test to detect amyloid plaques in the brain associated with Alzheimer's disease recently received clearance from the U.S. Food and Drug Administration. An Indiana University School of Medicine researcher who helped lead the discovery and development of one of the biomarkers the test identifies hopes it will provide greater access and a more accurate diagnosis for patients.

16 Jun 2025

Late-life mood disorders may signal neurodegenerative diseases

Depression and bipolar disorder of late onset may represent more than just mental health conditions. Growing evidence suggests these late-life mood disorders (LLMDs) could be not merely risk factors, but rather early warning signs of neurodegenerative diseases like dementia, even when they appear years before memory loss or other cognitive symptoms become apparent.

9 Jun 2025

Blood test shows high accuracy in detecting Alzheimer's disease

Alzheimer's disease, marked by memory loss, trouble concentrating and thinking, and changes in personality and behavior, devastates patients, their families and loved ones.

6 Jun 2025

Decade-long brain study offers new insights into aging

Researchers from The University of Texas at Dallas' Center for Vital Longevity (CVL) have released the full dataset from a decade-long project designed to track brain and cognitive health as people age and distinguish neurologically healthy paths from those indicating a likelihood of decline.

28 May 2025

Blood test pinpoints early Alzheimer’s risk with high accuracy

Researchers evaluated a fully automated plasma biomarker panel to detect early amyloid-β accumulation in cognitively unimpaired adults at risk for Alzheimer’s disease. Plasma p-tau217/Aβ42 emerged as the most robust and accurate blood-based marker for identifying preclinical amyloid pathology.

26 May 2025

Motivation for healthy habits declines after learning Alzheimer’s risk

Learning about one's risk for Alzheimer's disease may not lead to emotional distress, but motivation to maintain healthy lifestyle changes tends to fade over time, even in people at high risk, according to a study involving a Rutgers Health researcher.

7 May 2025

Hidden heart and lung damage detected in patients with long COVID

Patients suffering from long COVID may exhibit persistent inflammation in the heart and lungs for up to a year following SARS-CoV-2 infection-even when standard medical tests return normal results-potentially placing them at elevated risk for future cardiac and pulmonary conditions.

6 May 2025