Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

$3.7 million grant supports research on perimenopause and its potential impacts on mental health

For decades, women's midlife experiences have been largely overlooked by medical research. Despite previous assumptions about midlife mental health risks, relatively little research has systematically investigated the connections between hormonal fluctuations and psychological symptoms.

6 Oct 2025

Depression and psychosis rise after childbirth while suicide risk declines

Depression and psychosis are more common in women after childbirth than before, but the risk of suicide attempts decreases. This is shown by two new studies from Karolinska Institutet.

25 Sep 2025

Racial discrimination linked to greater psychosis risk

Being racially or ethnically discriminated against may increase the risk of later developing psychotic symptoms, finds a major review of international evidence led by UCL (University College London) researchers.

24 Sep 2025

New app can help young adults with first-episode psychosis to better manage cannabis use

Scientists at Université de Montréal's affiliated hospital research centre (CRCHUM) are testing out a mobile application to help young adults who have a first episode of psychosis to support safer cannabis consumption.

24 Sep 2025

Hyperemesis gravidarum associated with increased neuropsychiatric disorders in pregnancy

The largest study on pregnant women with excessive nausea and vomiting (hyperemesis gravidarum) has identified increased risks of numerous neuropsychiatric and mental health outcomes.

18 Sep 2025

Dementia risk rises sharply with multiple psychiatric disorders

The odds of developing dementia are strongly linked to the number of co-existing mental health disorders, rising from twice as high for one disorder to 11 times as high for four or more, finds research published in the open access journal BMJ Mental Health.

9 Sep 2025

Global mental health crisis demands urgent investment and action

More than 1 billion people are living with mental health disorders, according to new data released by the World Health Organization (WHO), with conditions such as anxiety and depression inflicting immense human and economic tolls.

2 Sep 2025

Using cannabis to self medicate linked to higher risk of paranoia

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London, in partnership with the University of Bath, has found that the reasons why a person chooses to use cannabis can increase their risk of developing paranoia.

27 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Patients recall inadequate disclosure of electroconvulsive therapy risks

The medical pros of electroconvulsive therapy (ECT) are being exaggerated while the risks are being downplayed, suggest the findings of a survey on the type of information patients and their relatives/friends recall having been given before the procedure, and published online in the Journal of Medical Ethics.

17 Aug 2025

Flu virus triggers neuropsychiatric symptoms not the medication

For decades, medical professionals debated whether a common antiviral medication used to treat flu in children caused neuropsychiatric events or if the infection itself was the culprit.

4 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

Mexican neuroscientist's journey from exile to schizophrenia research breakthroughs

In a revealing Genomic Press Interview published today in Brain Medicine, Dr. Camilo de la Fuente-Sandoval shares how personal history and scientific passion converged to create groundbreaking advances in schizophrenia treatment prediction.

29 Jul 2025

New insights into social factors shaping mental health outcomes

Mental illnesses are thought to be caused by both biological and environmental factors in complex interaction.

22 Jul 2025

Study reveals a connection between grip strength, well-being and the brain's default mode network

A study published June 25 in the American Journal of Psychiatry provides new insights into a long-standing question in psychiatric research: What is the underlying neurobiological mechanism of psychomotor disturbance in psychiatric disorders?

8 Jul 2025

Virtual Reality therapy works very well for people with psychosis

Treatment with Virtual Reality appears to work very well for people with psychosis. It works faster than the current treatment with cognitive behavioral therapy and is at least as effective.

7 Jul 2025

Synthetic opioids and designer benzodiazepines linked to driving impairment

No-one could claim to be unaware of the dangers of driving under the influence of drugs (DUID): drugs can increase the time needed to react, impair coordination, alertness, and cognition, and lower inhibitions, thus encouraging reckless and aggressive driving.

25 Jun 2025