Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Study isolates mania-specific genetic architecture in bipolar disorder

Researchers at King's College London and the University of Florence have, for the first time, identified the specific genetic blueprint of mania, the defining feature of bipolar disorder.

27 Jan 2026

Central reference database launched to categorize and coordinate mental health biomarker research

Psychiatrists and neuroscientists are taking a major step toward objective mental health diagnosis by launching a central reference database for the classification and communication of mental health biomarker research.

19 Jan 2026

Study finds growing long-term antipsychotic prescribing in elderly dementia patients

When agitated dementia patients wander or shout through the night, families and caregivers understandably feel the need to treat this frightening and potentially dangerous behavior. Antipsychotic medications are often resorted to with such patients, contributing to increases in antipsychotic treatment rates among older people.

16 Jan 2026

Smoking cessation drug shows promise for treating cannabis use disorder

A new randomized controlled trial has found promising evidence that the smoking cessation medication varenicline (Chantix/Champix) can help people with cannabis use disorder (CUD) to reduce cannabis use.

15 Jan 2026

Researchers map how brain networks differ in individuals at high clinical risk for psychosis

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and NHG Health's Institute of Mental Health (IMH) have mapped how brain networks differ in individuals at Clinical High Risk (CHR) for psychosis, providing a new perspective on the mechanisms underlying the disease onset.

10 Dec 2025

Study reveals the overlooked mental health challenges faced by new parents

Intrusive thoughts and psychotic-like experiences among new parents are far more common than previously thought - according to new research from the University of East Anglia.

2 Dec 2025

Moderate coffee intake linked to slower biological aging in people with severe mental illness

Drinking a maximum of 3-4 cups of coffee a day may slow the 'biological' ageing of people with severe mental illness, by lengthening their telomeres-indicators of cellular ageing-and giving them the equivalent of 5 extra biological years, compared with non-coffee drinkers, finds research published in the open access journal BMJ Mental Health.

25 Nov 2025

Large language models revolutionize psychiatric questionnaires

Large language models can help improve questionnaires used to diagnose mental illness by optimizing symptom generalizability and reducing redundancy.

18 Nov 2025

Novel therapy for psychosis tackles disturbing mental imagery

A pioneering therapy targeting distressing and disturbing mental images for people with psychosis could lead to a transformative intervention for a condition estimated to cost England almost £12 billion a year.

6 Nov 2025

Researchers identify patient response patterns to novel schizophrenia medication

Each year, about 100,000 Americans experience psychosis, a serious condition that disrupts thoughts and perceptions so profoundly that it can distort a person's sense of reality.

6 Nov 2025

International experts urge the reclassification of postpartum psychosis to improve treatment

An international panel of leading women's mental health experts – including UVA Health's Jennifer Payne, MD – is calling to reclassify postpartum psychosis as its own category of mental illness to improve the care new mothers receive.

3 Nov 2025

Dermatological symptoms could signal higher risk in psychiatric patients

Scientists have discovered that mental health patients who have skin conditions may be more at risk of worse outcomes, including suicidality and depression.

13 Oct 2025

Study links skin conditions to worse outcomes in mental health patients

Scientists have discovered that mental health patients who have skin conditions may be more at risk of worse outcomes, including suicidality and depression.

9 Oct 2025

$3.7 million grant supports research on perimenopause and its potential impacts on mental health

For decades, women's midlife experiences have been largely overlooked by medical research. Despite previous assumptions about midlife mental health risks, relatively little research has systematically investigated the connections between hormonal fluctuations and psychological symptoms.

6 Oct 2025

Depression and psychosis rise after childbirth while suicide risk declines

Depression and psychosis are more common in women after childbirth than before, but the risk of suicide attempts decreases. This is shown by two new studies from Karolinska Institutet.

25 Sep 2025

Racial discrimination linked to greater psychosis risk

Being racially or ethnically discriminated against may increase the risk of later developing psychotic symptoms, finds a major review of international evidence led by UCL (University College London) researchers.

24 Sep 2025

New app can help young adults with first-episode psychosis to better manage cannabis use

Scientists at Université de Montréal's affiliated hospital research centre (CRCHUM) are testing out a mobile application to help young adults who have a first episode of psychosis to support safer cannabis consumption.

24 Sep 2025

Hyperemesis gravidarum associated with increased neuropsychiatric disorders in pregnancy

The largest study on pregnant women with excessive nausea and vomiting (hyperemesis gravidarum) has identified increased risks of numerous neuropsychiatric and mental health outcomes.

18 Sep 2025

Dementia risk rises sharply with multiple psychiatric disorders

The odds of developing dementia are strongly linked to the number of co-existing mental health disorders, rising from twice as high for one disorder to 11 times as high for four or more, finds research published in the open access journal BMJ Mental Health.

9 Sep 2025

Global mental health crisis demands urgent investment and action

More than 1 billion people are living with mental health disorders, according to new data released by the World Health Organization (WHO), with conditions such as anxiety and depression inflicting immense human and economic tolls.

2 Sep 2025