Abdominal Pain News and Research

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Abdominal pain is traditionally described by its chronicity (acute or chronic), its progression over time, its nature (sharp, dull, colicky), its distribution (by various methods, such as abdominal quadrant (left upper quadrant, left lower quadrant, right upper quadrant, right lower quadrant) or other methods that divide the abdomen into nine sections), and by characterization of the factors that make it worse, or alleviate it.

ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients

Data from the 48-week ART trial, presented today at the Digestive Disease Week meeting, showed that remission and response rates were 37.2% and 53.2% respectively at week 12, in patients with moderate-to-severe, steroid-dependent active ulcerative colitis (UC) with insufficient response or intolerance to immunosuppressants and / or biologics when treated with between five and eight sessions with Adacolumn.

26 May 2016

Nutrition, safety tips for grilling season

Cooking meat, including beef, pork, fish, or poultry, with high-temperature methods such as pan frying or grilling directly over an open flame can increase exposure to chemicals that can cause changes in DNA that may increase the risk of cancer, according to the National Cancer Institute.

25 May 2016

Diet-based therapy may improve quality of life in IBS patients

A change in diet can improve the lives of those diagnosed with a common, but hard-to-treat gut disorder.

25 May 2016

Rotavirus vaccine program reduces hospitalization rates by more than 70% in Ontario

Hospitalization for rotavirus infections decreased by > 70% following the introduction of a vaccine program in Ontario, Canada, according to a study published May 11, 2016 in the open-access journal PLOS ONE by Sarah Wilson from Public Health Ontario and the Institute for Clinical Evaluative Sciences, Canada, and colleagues.

13 May 2016

Genetic variations that prevent beneficial gut bacteria from working may lead to Crohn's disease

A major type of inflammatory bowel disease (IBD) may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new study published today in the journal Science.

6 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

First generic version of Crestor gets FDA approval

The U.S. Food and Drug Administration today approved the first generic version of Crestor (rosuvastatin calcium) tablets.

30 Apr 2016

Pediatric researchers develop minimally invasive techniques to treat plastic bronchitis

Pediatric researchers have devised an innovative, safe and minimally invasive procedure that helps relieve rare but potentially life-threatening airway blockages occurring in children who had surgery for congenital heart defects.

22 Apr 2016

Non-invasive test to diagnose EoE could replace need for repeated endoscopy

A non-invasive test to diagnose and monitor an inflammatory disease that injures the esophagus - called eosinophilic esophagitis or EoE - would replace the need for repeated endoscopy for a growing number of children and adults with this relatively new condition.

21 Apr 2016

Taking antibiotics in early childhood can disrupt immune system function lifelong

Scientists want to know whether taking antibiotics early in life can disrupt your immune system function lifelong.

15 Apr 2016

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

RedHill Biopharma Ltd. (NASDAQ; RDHL) (TASE: RDHL) (“RedHill” or the “Company”), a biopharmaceutical company primarily focused on development and commercialization of late clinical-stage, proprietary, orally-administered, small molecule drugs for inflammatory and gastrointestinal diseases, including cancer, today announced that it has initiated a randomized, double-blind, 2-arm parallel group Phase II clinical study in the U.S. evaluating the safety and efficacy of BEKINDA™ 12 mg in patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

13 Apr 2016

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Sepsis represents a serious complication of infection and is one of the leading causes of death and critical illness worldwide due in part to the lack of effective therapies. A report in the American Journal of Pathology provides evidence from both mouse and human studies that SHARPIN, a protein involved in regulating inflammation, has anti-septic effects. These findings may spur development of novel sepsis treatments.

11 Apr 2016

Sleep problems predict chronic pain in emerging adults

For at least some groups of "emerging adults," sleep problems are a predictor of chronic pain and worsening pain severity over time, suggests a study in PAIN, the official publication of the International Association for the Study of Pain.

2 Apr 2016

UCI researchers get $8 million to help develop new vaccine for Q fever

A University of California, Irvine scientific team led by infectious diseases researchers Philip Felgner and Aaron Esser-Kahn has received $8 million from the U.S. Department of Defense's Defense Threat Reduction Agency to help develop a new vaccine for Q fever.

29 Mar 2016

Most patients prefer portable media devices to face-to-face consultation when discussing surgery

Often patients undergo procedures without real informed consent being achieved due to technical language, jargon and time pressure, with up to half of patients finding it difficult to understand what their doctor tells them. Now a group of Australian doctors has prepared patients for surgery using iPads, and found that patients' understanding was much better than after a face-to-face consultation.

14 Mar 2016

Simple method to determine prevalence of celiac disease in children aged 2-4

Researchers from the University of Granada have developed a new, simple and non invasive method which allows to determine whether a child aged 2-4 suffers from celiac disease or not without the necessity of a blood extraction.

11 Mar 2016

RUVICA (ibrutinib) capsules approved for treatment-naïve CLL patients

The U.S. Food and Drug Administration has approved IMBRUVICA (ibrutinib) capsules for treatment-naïve patients with chronic lymphocytic leukemia (CLL).

4 Mar 2016

Out-of-towners using marijuana in Colorado end up in emergency room

Out-of-towners using marijuana in Colorado -- which has legally allowed sales of the drug in retail dispensaries since 2014 -- are ending up in the emergency room at an increasing rate, reports a new study from Northwestern Medicine and the University of Colorado School of Medicine.

26 Feb 2016

Study finds no evidence of lactase deficiency specific to autistic children with GI symptoms

Children with autism have no unique pattern of abnormal results on endoscopy or other tests for gastrointestinal (GI) disorders, compared to non-autistic children with GI symptoms, reports a study in the Journal of Pediatric Gastroenterology and Nutrition, official journal of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

26 Feb 2016

Acute mesenteric ischemia can be treated with balloon angioplasty

Acute mesenteric ischemia (AMI) can be successfully treated with endovascular therapy such as balloon angioplasty, according to research from the University of Eastern Finland. The study also found that AMI is a more common cause of abdominal pain among the elderly than generally thought; however, it is difficult to diagnose before bowel damage develops.

26 Feb 2016

Abdominal Pain News and Research

Further Reading

ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients

Nutrition, safety tips for grilling season

Diet-based therapy may improve quality of life in IBS patients

Rotavirus vaccine program reduces hospitalization rates by more than 70% in Ontario

Genetic variations that prevent beneficial gut bacteria from working may lead to Crohn's disease

Bayer-new phase 3 liver cancer data

First generic version of Crestor gets FDA approval

Pediatric researchers develop minimally invasive techniques to treat plastic bronchitis

Non-invasive test to diagnose EoE could replace need for repeated endoscopy

Taking antibiotics in early childhood can disrupt immune system function lifelong

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Sleep problems predict chronic pain in emerging adults

UCI researchers get $8 million to help develop new vaccine for Q fever

Most patients prefer portable media devices to face-to-face consultation when discussing surgery

Simple method to determine prevalence of celiac disease in children aged 2-4

RUVICA (ibrutinib) capsules approved for treatment-naïve CLL patients

Out-of-towners using marijuana in Colorado end up in emergency room

Study finds no evidence of lactase deficiency specific to autistic children with GI symptoms

Acute mesenteric ischemia can be treated with balloon angioplasty

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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