Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

E-cigarettes stress and inflame the lungs, impair key regulatory proteins

E-cigarettes stress and inflame the lungs of rats, compromising important regulatory proteins through exposure, according to research recently published in the journal Redox Biology.

18 Jan 2021

Religious beliefs modulate protein expression linked to cardiovascular disease in US South Asians

The Study on Stress, Spirituality and Health (SSSH), a cutting-edge proteomics analysis, suggests that religious beliefs modulate protein expression associated with cardiovascular disease in South Asians in the United States.

15 Jan 2021

New technology helps study muscle biology more clearly

Exercising regularly is one of the best defenses against metabolic diseases, such as obesity and diabetes - but why? It's a question that scientists are still struggling to answer. While exercising changes the molecular behavior of muscles, it's not well understood how these molecular changes improve metabolic health.

13 Jan 2021

Bruker and Evosep announce major progress in unbiased, quantitative true single-cell proteomics

Bruker Corporation and Evosep today announced major progress in high-sensitivity, quantitative true single-cell proteomics, using a modified timsTOF Pro mass spectrometer connected to an Evosep One low-flow chromatography system.

From Bruker Daltonics 8 Jan 2021

Researchers provide comprehensive molecular characterization of head and neck cancers

In what is believed to be the most comprehensive molecular characterization to date of the most common type of head and neck cancer, researchers from the Johns Hopkins departments of pathology and oncology, the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine, and 18 other centers around the U.S. and Poland have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in these cancers, while proposing possible new treatment avenues.

7 Jan 2021

Researchers receive $2.95 million grant to create improved diagnostics for worm infections

Global campaigns to eliminate two tropical parasitic worm infections have been hindered by a lack of good diagnostic tools.

7 Jan 2021

Anti-SARS-CoV-2 NTD-directed antibodies are protective against lethal infection

As the world struggles to contain the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for over 1.6 million deaths and 76 million infections globally, researchers are trying to pin down the determinants of lethality, of infectivity and of protection. Such data would help contain its spread and develop preventive and therapeutic antivirals and vaccines. A new preprint that appeared recently on the bioRxiv* server describes the high degree of protection afforded by antibodies that target the N-terminal domain (NTD) of the virus.

24 Dec 2020

Scientists discover molecular defects associated with rare genetic disorder in children

Damien D'Amours and his team at the Ottawa Institute of Systems Biology needed three years to discover the molecular defects associated with the LIC Syndrome, a serious genetic disorder that affects young children and result in acute respiratory distress, immune deficiency and abnormal chromosomes.

22 Dec 2020

Researchers identify new target that may lead to novel treatment for Alzheimer’s disease

Researchers at the Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer's disease (AD) that could lead to therapies focused on treating the neurodegenerative condition early in its progression.

7 Dec 2020

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

The onset of any physical exercise program causes muscle pain that can hinder movements as simple as getting up from a sofa. With time and a little persistence, the muscles become accustomed to the effort, developing more strength and endurance.

1 Dec 2020

World’s largest proteomics centre accelerates biomarker discoveries to improve people’s lives

Opened in 2016, Manchester’s Stoller Biomarker Discovery Centre (SBDC) is a globally renowned, multi-million-pound precision medicine research facility.

From Stoller Biomarker Discovery Centre 30 Nov 2020

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Researchers at Baylor College of Medicine, the Broad Institute of MIT and Harvard and other institutions have applied powerful proteogenomics approaches to better understand the biological complexity of breast cancer.

18 Nov 2020

Affinity-Bead Assisted Mass Spectrometry for Proteomics

In this interview, Ghaith Hamza from AstraZeneca talks to News-Medical Life Sciences about the basic principles of Affinity-Bead Assisted Mass Spectrometry (Affi-BAMS) and how Affi-BAMS can help target specific proteins for proteomic applications.

From Bruker Daltonics 16 Nov 2020

Researchers identify prognostic markers that could guide COVID-19 management

A team of researchers in Europe has created a comprehensive data resource to help improve understanding of how coronavirus disease 2019 (COVID-19) progresses and how biomarkers could be used to guide treatment approaches and disease monitoring.

15 Nov 2020

Novel mutations in SARS-CoV-2 may explain high pathogenicity of COVID-19

Researchers in Korea and the United States have identified novel genetic variants that demonstrate the active mutational progression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Nov 2020

Harnessing proteomics could improve therapeutic approaches to COVID-19

A research group in India has recently described how the field of proteomics could be pivotal in helping to tackle the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Sterile spikelets improve yield in sorghum and related grasses, shows study

Much of the food we eat comes from grasses such as rice, wheat, corn, sorghum, and sugarcane. These crops still resemble the wild species from which they were derived. In all grasses the structures that contain the flowers and seeds are called spikelets.

5 Nov 2020

Researchers gain novel insights into the role of autophagy in neurons

It appears that autophagy protects our neurons in the brain, but evidently for entirely different reasons than previously assumed, as researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Charité in Berlin have now shown.

5 Nov 2020

Science and technology award awarded to scientists at Bruker Daltonics

The Science and Technology Award recognizes an individual or team in private industry who played a key role in the commercialization of proteomics technology, product, or procedure.

From Bruker Daltonics 3 Nov 2020

Bruker introduces Vutara™ VXL best-in-class super-resolution microscope and spatial biology analysis capabilities

Bruker Corporation today announced the release of the Vutara VXL Super-Resolution Fluorescence Microscope for nanoscale biological imaging. The new system opens an affordable and easy-to-use path for both core facilities and individual investigators to enter the world of super-resolution imaging by incorporating Bruker’s industry-leading single-molecule localization (SML) technology in a streamlined system with compact footprint.

From Bruker Nano Surfaces and Metrology 23 Oct 2020

Proteomics News and Research

Further Reading

E-cigarettes stress and inflame the lungs, impair key regulatory proteins

Religious beliefs modulate protein expression linked to cardiovascular disease in US South Asians

New technology helps study muscle biology more clearly

Bruker and Evosep announce major progress in unbiased, quantitative true single-cell proteomics

Researchers provide comprehensive molecular characterization of head and neck cancers

Researchers receive $2.95 million grant to create improved diagnostics for worm infections

Anti-SARS-CoV-2 NTD-directed antibodies are protective against lethal infection

Scientists discover molecular defects associated with rare genetic disorder in children

Researchers identify new target that may lead to novel treatment for Alzheimer’s disease

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

World’s largest proteomics centre accelerates biomarker discoveries to improve people’s lives

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Affinity-Bead Assisted Mass Spectrometry for Proteomics

Researchers identify prognostic markers that could guide COVID-19 management

Novel mutations in SARS-CoV-2 may explain high pathogenicity of COVID-19

Harnessing proteomics could improve therapeutic approaches to COVID-19

Sterile spikelets improve yield in sorghum and related grasses, shows study

Researchers gain novel insights into the role of autophagy in neurons

Science and technology award awarded to scientists at Bruker Daltonics

Bruker introduces Vutara™ VXL best-in-class super-resolution microscope and spatial biology analysis capabilities

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