Small Cell Lung Cancer News and Research

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Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. Small cell lung cancer is an aggressive (fast-growing) cancer that can spread to other parts of the body. The cancer cells look small and oval-shaped when looked at under a microscope.

Customary drug dose for treatment of lung cancer may be higher than needed, study shows

A new study published in the Journal of the National Cancer Institute indicates that the customary pembrolizumab dose for treatment of metastatic non-small cell lung cancer may be higher than is needed for effective treatment.

6 Jun 2017

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Findings from a phase III clinical trial point to a potential new treatment for patients newly diagnosed with advanced, epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer (NSCLC).

5 Jun 2017

New genomic sequencing approach could be first step toward blood tests for early cancer detection

In a study of 124 patients with advanced breast, lung, and prostate cancers, a new, high-intensity genomic sequencing approach detected circulating tumor DNA at a high rate.

5 Jun 2017

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Novartis today announced the US Food and Drug Administration approved the expanded use of Zykadia (ceritinib) to include the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive, as detected by an FDA-approved test.

27 May 2017

Some types of cancers are heavily dependent on sugar, study shows

In a new study, scientists at The University of Texas at Dallas have found that some types of cancers have more of a sweet tooth than others.

26 May 2017

Immunotherapy can be more effective in NSCLC patients who received radiation therapy, study shows

A new study by UCLA scientists has found that the breakthrough immunotherapy drug pembrolizumab can be more effective in improving survival in people with non-small cell lung cancer (NSCLC) if they have previously received radiation therapy, compared to those without a history of radiation treatment.

25 May 2017

NCCN ORP funds researchers to evaluate targeted treatment in EGFRm+ non-small cell lung cancer

The National Comprehensive Cancer Network Oncology Research Program has funded two investigators from NCCN Member Institutions through a collaborative scientific research relationship with AstraZeneca to further evaluate the clinical effectiveness of osimertinib in the treatment of epidermal growth factor receptor-positive (EGFRm+) non-small cell lung cancer (NSCLC).

25 May 2017

Aggressive care in final days of life for advanced cancer patients not linked to better outcomes

For patients with advanced cancer, aggressive care -- chemotherapy, mechanical ventilation, acute hospitalizations and intensive care unit admissions -- at the end of life is commonplace.

25 May 2017

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences.

23 May 2017

FDA grants accelerated approval to cancer treatment based on common biomarker

The U.S. Food and Drug Administration today granted accelerated approval to a treatment for patients whose cancers have a specific genetic feature (biomarker).

23 May 2017

Targeted therapy appears to be more effective in preventing lung cancer recurrence

The targeted therapy gefitinib appears more effective in preventing recurrence after lung cancer surgery than the standard of care, chemotherapy.

18 May 2017

Tumor mutation load in patient's biopsy varies by age and type of cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that the tumor mutation load, or TML, in a patient's cancer biopsy varied by age and the type of cancer, along with several other factors.

18 May 2017

Study: Use of white blood cell boosting drugs found to be safe during chemo-radiotherapy of lung cancer

A late breaking subanalysis of the phase III CONVERT trial presented at the European Lung Cancer Conference shows that white blood cell boosting drugs are safe during concurrent chemo-radiotherapy of small cell lung cancer (SCLC).

5 May 2017

Takeda announces accelerated approval from FDA for new lung cancer treatment

Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that ALUNBRIG (brigatinib) has received Accelerated Approval from the U.S. Food and Drug Administration for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.

28 Apr 2017

Unstable chromosomes in lung tumors increase risk of cancer relapse, study reveals

The New England Journal of Medicine and Nature has published the first findings from the Cancer Research UK-funded Tracking Cancer Evolution through Treatment (Rx), TRACERx, lung cancer study, which reveals the increase in the risk of cancer relapse when lung tumors have unstable chromosomes.

27 Apr 2017

Understanding and predicting tumor resistance may open door to additional treatment options

A collaborative Cleveland Clinic, University of Oxford and Moffitt Cancer Center team of researchers has proven the theory that, while resistance to targeted treatment in cancer is truly a moving target, there are opportunities to overcome the resistance that develops.

27 Apr 2017

Drug shows early promise in treating patients with small-cell lung cancer

An early round of clinical testing shows that users of Opdivo, a drug sanctioned for treatment of small-cell lung cancer, more than tripled their five-year survival rate beyond the statistical average.

20 Apr 2017

New blood test can accurately, quickly identify genetic mutations linked to NSCLC

Identification of a specific genetic mutation in patients with non-small-cell lung cancer (NSCLC) helps clinicians select the best treatment option. Potential NSCLC patients usually undergo invasive tissue biopsy, which may often be unnecessary and delays treatment.

19 Apr 2017

Penn State researchers develop nanoprobes to rapidly isolate rare cancer markers

A nanoscale product of human cells that was once considered junk is now known to play an important role in intercellular communication and in many disease processes, including cancer metastasis.

10 Apr 2017

OSU scientists find way to fight solid tumors using new cancer-drug delivery system

A new cancer-drug delivery system shows the ability to exploit the oxygen-poor areas of solid tumors that make the growths resistant to standard chemotherapy and radiation treatment.

4 Apr 2017

Small Cell Lung Cancer News and Research

Customary drug dose for treatment of lung cancer may be higher than needed, study shows

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

New genomic sequencing approach could be first step toward blood tests for early cancer detection

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Some types of cancers are heavily dependent on sugar, study shows

Immunotherapy can be more effective in NSCLC patients who received radiation therapy, study shows

NCCN ORP funds researchers to evaluate targeted treatment in EGFRm+ non-small cell lung cancer

Aggressive care in final days of life for advanced cancer patients not linked to better outcomes

Study points to new pharmacologic approach to target chemo-resistant lung cancer

FDA grants accelerated approval to cancer treatment based on common biomarker

Targeted therapy appears to be more effective in preventing lung cancer recurrence

Tumor mutation load in patient's biopsy varies by age and type of cancer

Study: Use of white blood cell boosting drugs found to be safe during chemo-radiotherapy of lung cancer

Takeda announces accelerated approval from FDA for new lung cancer treatment

Unstable chromosomes in lung tumors increase risk of cancer relapse, study reveals

Understanding and predicting tumor resistance may open door to additional treatment options

Drug shows early promise in treating patients with small-cell lung cancer

New blood test can accurately, quickly identify genetic mutations linked to NSCLC

Penn State researchers develop nanoprobes to rapidly isolate rare cancer markers

OSU scientists find way to fight solid tumors using new cancer-drug delivery system

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