Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

Two immunotherapies used together for the first time to fight against solid tumors

Two immunotherapies - one that enables the T-cells a patient already has to better attack a tumor and another that can produce an independent and vigorous immune response - are being given together for the first time to help more patients wage a stronger war on a wide range of solid tumors, researchers say.

26 Mar 2018

Gut microbiome may promote pancreatic cancer by inducing immune suppression

Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain "bad" bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

22 Mar 2018

Blood donor scraps help researchers to discover new insight into human immune system

Iowa State University researchers have discovered new insight into the human immune system from an unlikely source, the leftover material from blood donation banks.

16 Mar 2018

Improved methods for capture of circulating tumor cells could help in disease tracking

Tumor cells circulating throughout the body in blood vessels have long been feared as harbingers of metastasizing cancer - even though most free-floating cancer cells will not go on to establish a new tumor.

15 Mar 2018

Sartorius Stedim Biotech unveils new ambr 250ht perfusion system for cell culture process development

Sartorius Stedim Biotech, a leading international supplier for the biopharmaceutical industry today announced the launch of the ambr 250 high throughput (ht) perfusion, a new automated parallel bioreactor system.

From Sartorius 15 Mar 2018

MIT engineers develop new technology that could improve drug evaluation

MIT engineers have developed new technology that could be used to evaluate new drugs and detect possible side effects before the drugs are tested in humans.

14 Mar 2018

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

13 Mar 2018

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

Among patients with persistently high cholesterol despite high-intensity statin therapy, the proprotein convertase subtilisin-kexin 9 (PCSK9) inhibitor alirocumab reduced rates of major adverse cardiovascular events by 15 percent compared with placebo, in a study presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

Innovative antibody delivery method could offer effective way to combat Ebola infection

More than 11,000 people died during the Ebola outbreak in West Africa from 2013-16, demonstrating both the deadly nature of the virus and the limitations of the medication used to fight it.

6 Mar 2018

Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

If you're an immune cell gearing up to fight cancer, you'd better eat your breakfast. The tumor microenvironment is a harsh place, and tumor cells are ready to wear you out.

6 Mar 2018

Experts develop process for marker-free cell selection

At this year's analytica trade fair in Munich, three Fraunhofer Institutes will be presenting a project from pre-competitive research. Biologists, computer scientists and laser experts have developed a process to analyze and select cells and then examine their protein production. In pharmaceutical research, this will make it possible to develop active ingredients much faster than before.

6 Mar 2018

Study uncovers new target in Parkinson’s disease

A new study has uncovered a relationship between the presence of Lewy bodies and neuronal cell death in Parkinson's disease.

6 Mar 2018

TSRI research offers explanation for why neurons die off in Parkinson's disease

An estimated 10 million people worldwide are living with Parkinson's disease--an incurable neurodegenerative disorder that leads to an increasing loss of motor control.

6 Mar 2018

The Neuro and Thermo Fisher Scientific team up to accelerate understanding of neurological disease

The Montreal Neurological Institute of McGill University, a world-leading institution focused on brain research and advanced patient care, and Thermo Fisher Scientific, the world leader in serving science, today announce an agreement designed to accelerate the understanding of neurological disease by focusing on about 30 proteins associated with Parkinson's disease, amyotrophic lateral sclerosis (ALS), hereditary spastic paraplegias, epileptic encephalopathies and ataxias, which are all devastating brain diseases.

5 Mar 2018

Johns Hopkins researchers invent new class of immunotherapy drugs to fight cancer

Johns Hopkins researchers have invented a new class of cancer immunotherapy drugs that are more effective at harnessing the power of the immune system to fight cancer.

2 Mar 2018

USC scientists use metal-detection technique to study cancer

Metal detection has helped mining companies strike gold and airport security identify passengers who are a potential threat. Now USC scientists have pushed its use into another realm: studying cancer.

28 Feb 2018

Researchers developing rapid saliva test to detect Zika virus

Researchers at New York University College of Dentistry, in collaboration with Rheonix, Inc., are developing a novel test for Zika virus that uses saliva to identify diagnostic markers of the virus in a fraction of the time of current commercial tests.

24 Feb 2018

U.S. clinical sites evaluating antibody-based therapies to prevent two common bacterial infections

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, is supporting U.S. clinical sites participating in two ongoing international Phase 2 clinical trials evaluating investigational antibody-based therapies aimed at preventing potentially antibiotic-resistant infections.

23 Feb 2018

Antibody News and Research

Further Reading

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Antibody sweeps away Alzheimer's plaques in mice

Two immunotherapies used together for the first time to fight against solid tumors

Gut microbiome may promote pancreatic cancer by inducing immune suppression

Blood donor scraps help researchers to discover new insight into human immune system

Improved methods for capture of circulating tumor cells could help in disease tracking

Sartorius Stedim Biotech unveils new ambr 250ht perfusion system for cell culture process development

MIT engineers develop new technology that could improve drug evaluation

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

Innovative antibody delivery method could offer effective way to combat Ebola infection

Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

Experts develop process for marker-free cell selection

Study uncovers new target in Parkinson’s disease

TSRI research offers explanation for why neurons die off in Parkinson's disease

The Neuro and Thermo Fisher Scientific team up to accelerate understanding of neurological disease

Johns Hopkins researchers invent new class of immunotherapy drugs to fight cancer

USC scientists use metal-detection technique to study cancer

Researchers developing rapid saliva test to detect Zika virus

U.S. clinical sites evaluating antibody-based therapies to prevent two common bacterial infections

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