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Promising COVID-19 drug treatments identified with new screening strategies

As scientists across the world race to find a pharmacological cure for coronavirus disease (COVID-19), an international research group has analyzed more than 10 thousand different compounds and identified six potential candidates, publishing their results in the leading scientific journal Nature.

12 Apr 2020

Recovered South Korean COVID-19 patients test positive again

Following the reports from different countries of patients recovered from coronavirus disease (COVID-19) but testing positive again during the control diagnostic appraisal, South Korea's Centers for Disease Control and Prevention (CDC) documents a similar occurrence in 51 patients.

12 Apr 2020

Unraveling interactions between metal ions and peptides may lead to new therapies for diseases

Copper ions could play a key role when peptide folding goes wrong and leads to harmful aggregates.

12 Apr 2020

Stuttering DNA controls development of mosquito embryos

All organisms have DNA, the genetic material that provides a blueprint for life. The long double-helix-shaped DNA molecules in the body's cells are first translated into RNA molecules and then translated into proteins that ensure the functioning of the cell and the entire organism.

12 Apr 2020

New computer model can screen drugs for unintended cardiac side effects

UC Davis Health researchers have developed a computer model to screen drugs for unintended cardiac side effects, especially arrhythmia risk.

12 Apr 2020

UMSOM launches new initiative to expand COVID-19 testing

University of Maryland School of Medicine Dean E. Albert Reece, MD, PhD, MBA, announced today the launch of a large-scale COVID-19 Testing Initiative that will significantly expand testing capability over the coming weeks, enabled by new funding of $2.5 million from the State of Maryland.

12 Apr 2020

Risks and benefits of separating infants from COVID-19-positive mothers

In a new commentary, Alison Stuebe, MD, President of the Academy of Breastfeeding Medicine, addresses the risks and benefits of separating infants from COVID-19-positive mothers following birth.

12 Apr 2020

PARP inhibitor drugs can be structurally modified to better kill tumor cells

A prospective "PARP inhibitor" drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor cells, researchers from Penn Medicine report this week in Science.

12 Apr 2020

Vaccine skeptics may process information differently than people

In 2000, the measles virus was declared eliminated from the United States. Despite cases coming in from outside the country, there were few outbreaks because most people were vaccinated against measles. And then 2019 happened.

12 Apr 2020

Surgeons report on rural preparedness response plan for dealing with COVID-19

Major metropolitan areas such as New York, Seattle, and Detroit have dominated news of the COVID-19 outbreak, but rural hospitals and health care systems must also prepare for a surge of coronavirus patients.

12 Apr 2020

FDA approves COVID-19 solutions created by Ohio State Medical Center scientists

The Food and Drug Administration has approved solutions created by scientists at The Ohio State University Wexner Medical Center that both expand and accelerate COVID-19 testing across Ohio.

12 Apr 2020

Highlighting the detrimental impact of global COVID-19 pandemic response on SRHR

The Lancet commentary "Centring sexual and reproductive health and justice in the global COVID-19 response" highlights the detrimental impact of the global COVID-19 pandemic response on sexual and reproductive health and rights.

12 Apr 2020

Researchers identify new risk gene for Parkinson's disease

Screening DNA of Parkinson's patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson's disease. Mutations in ATP10B resulted in loss of ATP10B protein.

12 Apr 2020

Recipients of 2020 Sleep Research Society awards announced

The Sleep Research Society has selected three outstanding sleep and circadian scientists as recipients of the 2020 Sleep Research Society awards, which recognize excellence in sleep and circadian research.

12 Apr 2020

UTSW researchers uncover shape of key protein involved in muscle contraction

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction. The report, published today in Neuron, may lead to improved understanding of muscle-weakening genetic conditions called congenital myasthenic syndromes.

12 Apr 2020

Where cancers spread can give specific insights on disease traits

Kidney cancers that metastasize to the pancreas have a fundamentally different biology from those that metastasize elsewhere, with characteristics that can influence successful treatment, a study led by investigators with the UT Southwestern Kidney Cancer Program suggests.

12 Apr 2020

Furor erupts: Billions going to hospitals based on Medicare billings, not COVID-19

Probably few hospital systems need the emergency federal grants announced this week to handle the coronavirus crisis as badly as Florida's Jackson Health does.

11 Apr 2020

New clinical trial launches to test efficacy of cell therapy for severe COVID-19 cases

After a lightening round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells to block the life-threatening lung inflammation that accompanies severe cases of COVID-19.

11 Apr 2020

Many of Washington State’s illicit drug users want to reduce use

A new survey of people who inject illicit drugs in the state of Washington yields positive and important findings for policy makers as the world struggles to deal with the COVID-19 pandemic, said authors of the survey by the University of Washington and Public Health-Seattle & King County.

11 Apr 2020

Free program to reduce and replace animal tests in scientific research

From June 22 to 25, students and early-career scientists will gather virtually for a free program of lectures, laboratory tours, interactive sessions, e-poster presentations, and virtual engagement with speakers and attendees on innovative methods to reduce and replace animal tests in toxicology and biomedical science.

11 Apr 2020