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Doctors are as vulnerable to addiction as anyone. California grapples with a response.

Ariella Morrow, an internal medicine doctor, gradually slid from healthy self-esteem and professional success into the depths of depression.

4 Jan 2024

New approach leverages macrophages to treat traumatic brain injury

Scientists have created a new treatment for traumatic brain injury (TBI) that shrank brain lesions by 56% and significantly reduced local inflammation levels in pigs.

3 Jan 2024

Missing proteins explain century-old mystery of scalp skin absence in children

Children with the condition aplasia cutis congenita (ACC) are born with the absence of skin along the midline of the scalp.

3 Jan 2024

Researchers uncover variations in how IBD affects people of different races, sexes and places of birth

Researchers from Rutgers and other institutions have uncovered significant variations in how inflammatory bowel disease (IBD) affects people of different races, sexes and places of birth.

3 Jan 2024

Factors that increase the risk of severe COVID-19 in children

Study analyzes a nationwide cohort of hospitalized children and adolescents in Germany, identifying key risk factors for severe SARS-CoV-2 infection, including obesity, Trisomy 21, and neurological conditions.

3 Jan 2024

Exploring environmental influences on pregnancy, child health and disabilities

How does a pregnant person's environment, diet, stress, medications and social wellbeing affect their pregnancy and - down the road - their child's health?

3 Jan 2024

New study demystifies clinicians' decision-making process for drug-drug interactions

Drug-drug interactions causing adverse effects are common and can cause significant patient harm and even death.

3 Jan 2024

Study reveals high prevalence of chronic pain in TBI patients

Chronic pain affects approximately 60% of people living with traumatic brain injury (TBI), even up to 30 years after injury, according to new research published in The Journal of Head Trauma Rehabilitation (JHTR), the official journal of the Brain Injury Association of America.

3 Jan 2024

New brain imaging technique sheds light on invisible mTBIs

Researchers have created a new brain imaging method that allows mild traumatic brain injuries (mTBIs) to be diagnosed, even when existing imaging techniques like magnetic resonance imaging (MRI) don't show any structural abnormalities.

3 Jan 2024

MGH study identifies key proteins linked to pregnancy hypertension disorders

Preeclampsia and other hypertensive disorders of pregnancy - which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy - carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

3 Jan 2024

Rare immune cell holds key to predicting melanoma treatment success

A type of immune cell can help predict which patients may benefit most from cancer immunotherapies, researchers from King's College London, Guy's and St Thomas' Hospital Trust, and the Francis Crick Institute have found.

3 Jan 2024

Patients with HPV-related head and neck cancers treated in community centers less likely to survive

Care for patients with human papillomavirus (HPV)-related squamous cell cancers of the oropharynx (an area in back of the throat) is shifting toward community cancer centers, but patients treated in this setting may be less likely to survive, according to new research by investigators from the Johns Hopkins Kimmel Cancer Center and its Head and Neck Cancer Center.

3 Jan 2024

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Mount Sinai researchers have shown for the first time that a person's beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

3 Jan 2024

Existing beta blocker investigated as novel sickle cell therapy

A beta blocker typically used to treat heart problems, hemangioma, migraines and anxiety could be a new therapeutic for patients with sickle cell disease. Researchers led by Ankit A. Desai, MD, associate professor of medicine at the Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine, have been awarded a $3 million grant by the U.S. Department of Defense to evaluate the efficacy of this drug.

3 Jan 2024

"Genetic priority score" promises to revolutionize drug development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score.

3 Jan 2024

Hospital News and Research

Doctors are as vulnerable to addiction as anyone. California grapples with a response.

New approach leverages macrophages to treat traumatic brain injury

Missing proteins explain century-old mystery of scalp skin absence in children

Researchers uncover variations in how IBD affects people of different races, sexes and places of birth

Factors that increase the risk of severe COVID-19 in children

Exploring environmental influences on pregnancy, child health and disabilities

New study demystifies clinicians' decision-making process for drug-drug interactions

Study reveals high prevalence of chronic pain in TBI patients

New brain imaging technique sheds light on invisible mTBIs

MGH study identifies key proteins linked to pregnancy hypertension disorders

Rare immune cell holds key to predicting melanoma treatment success

Patients with HPV-related head and neck cancers treated in community centers less likely to survive

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Existing beta blocker investigated as novel sickle cell therapy

"Genetic priority score" promises to revolutionize drug development

Cytonemes: The "express subways" of the developing nervous system

Heart-healthy diet boosts patient satisfaction and safety before cardiac catheterization

Novel exercise approach offers significant benefits for children with cerebral palsy

Patients with narcolepsy face a dual nightmare of medication shortages and stigma

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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