Genome News and Research

RSS

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

New review highlights how lifestyle affects our genes

In the past decade, knowledge of how lifestyle affects our genes, a research field called epigenetics, has grown exponentially.

24 Apr 2019

DNA rearrangement may predict poor outcomes in multiple myeloma

A certain type of DNA marker predicts poor outcomes in multiple myeloma, researchers at Winship Cancer Institute, Emory University have found.

24 Apr 2019

Researchers study how E. coli clones have become major cause of drug-resistant infections

A 'superbug' clone of E. coli has evolved to prevent itself from becoming so dominant that it could potentially wipe out the bacteria from existence, scientists led by the University of Birmingham have discovered.

23 Apr 2019

Researchers define role of rare, influential cells in the bone marrow

Researchers have defined the roles of various cells in the bone marrow that are thought to control the fate of the nearly half million blood cells that develop there each day.

23 Apr 2019

Novel ECCITE-seq technique expands multimodal single cell analysis

A new technique called ECCITE-seq, developed by scientists at the New York Genome Center's Technology Innovation Lab, allows researchers to perform high-throughput measurements of multiple modalities of information from single cells.

From 10x Genomics, Inc. 23 Apr 2019

Scientists identify 104 high-risk genes for schizophrenia

Using a unique computational "framework" they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute has identified 104 high-risk genes for schizophrenia.

23 Apr 2019

Study identifies possible therapeutic effects of curcumin on stomach cancer

Curcumin is widely used to impart color and flavor to food, but scientists have discovered that this yellow powder derived from the roots of the turmeric plant (Curcuma longa) can also help prevent or combat stomach cancer.

22 Apr 2019

Overlooked part of cell’s internal machinery may hold key to treating acute myeloid leukemia

Many individuals forced to fight an exceptionally aggressive form of the blood cancer acute myeloid leukemia (AML) don't survive more than five years.

22 Apr 2019

Hole-forming protein could help control cancer growth

Sometimes cells need to die. The process of cell death is encoded within the genome of all higher organisms to kill off cancerous cells, and as a normal part of development to shape a mass of embryonic cells into the organism it will become.

22 Apr 2019

New scoring system based on genetic markers predicts obesity risk at birth

Researchers have come up with a scoring system based on genetic markers that predicts an individual's inborn risk for obesity.

19 Apr 2019

Improving the quality of digital pathology imaging

There's a low-tech problem troubling the high-tech world of digital pathology imaging.

19 Apr 2019

Scientists deploy CRISPR gene-editing tool to engineer multiple edits

Scientists at Christiana Care Health System's Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments of DNA extracted from a human cell, according to a new study published today in The CRISPR Journal.

19 Apr 2019

Synthetic biologists add analog-to-digital signal processing to genetic circuitry of living cells

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells.

19 Apr 2019

KZFPs play a key role in the regulation of human genome

The human genome is fascinating. Once predicted to contain about a hundred thousand protein-coding genes, it now seems that the number is closer to twenty thousand, and maybe less.

19 Apr 2019

Researchers identify key clues to brain and pancreas development

Researchers have discovered a key clue into the development of the pancreas and brain by studying rare patients born without a pancreas.

19 Apr 2019

A comprehensive, centralized database of bovine milk compounds

Milk is a staple of the human diet, full of key nutrients such as protein, carbohydrates, fats, and vitamins. Cow's milk in particular is one of the most-used dairy products globally, with over 800 million tons produced annually according to the United Nations Food and Agriculture Organization.

17 Apr 2019

Study identifies how enterococci bacteria cause antibiotic-resistant bloodstream infections

A new study led by a research team from Massachusetts Eye and Ear and Harvard Medical School describes how bacteria adapted to the modern hospital environment and repeatedly cause antibiotic-resistant bloodstream infections.

17 Apr 2019

IDT partners with iGEM to support young researchers and promote scientific progress

As an advocate for researchers in synthetic biology, Integrated DNA Technologies is once again proudly partnering with the International Genetically Engineered Machine Foundation to support young researchers and promote scientific progress.

From Integrated DNA Technologies 17 Apr 2019

New study delves deeper into individual genomic differences than ever before

Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or "spelling mistakes" in the DNA sequence, but even more variation comes from structural variants, which include additions, deletions and rearrangements of large segments of DNA.

17 Apr 2019