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Neural organoids offer insight into mechanisms of dementia

Researchers at The Ohio State University Wexner Medical Center and College of Medicine have discovered a new way that neurons act in neurodegeneration by using human neural organoids – also known as "mini-brain" models – from patients with frontotemporal lobar degeneration (FTLD).

9 Apr 2025

Tooth and gum problems common among teenage footballers in England

The prevalence of tooth and gum issues among teenage (academy) professional footballers in England is high, finds research published in the open access journal BMJ Open Sport & Exercise Medicine.

9 Apr 2025

New hospital program helps opioid patients stay in treatment after discharge

Offering hospitalized patients who are struggling with opioid use disorder a medication to treat their addiction makes it more likely that they will continue with follow-up care after they are discharged, a new study finds.

9 Apr 2025

Rural hospitals and patients are disconnected from modern care

Leroy Walker arrived at the county hospital short of breath. Walker, 65 and with chronic high blood pressure, was brought in by one of rural Greene County’s two working ambulances.

9 Apr 2025

Study links food additive mixtures to increased risk of type 2 diabetes

Food additive mixtures are an everyday feature of our diets, especially through ultra-processed foods.

9 Apr 2025

Relaxation methods offer temporary relief for high blood pressure

Relaxation techniques may help lower high blood pressure-at least in the short term-but the longer term effects are unclear, finds a pooled data analysis of the existing research published in the open access journal BMJ Medicine.

9 Apr 2025

QRICH1 protein discovery opens new avenues for cancer and autoimmune therapies

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

New study seeks best way to support people quitting menthol cigarettes

Nearly half of Americans who smoke use menthol cigarettes that are harder to quit, driving up their health risks with every puff.

9 Apr 2025

Breakthrough nanoparticle delivery method targets brain inflammation for multiple conditions

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's disease, multiple sclerosis, Parkinson's disease and cancer cachexia.

9 Apr 2025

Food-as-medicine could save billions in healthcare costs—here’s what’s standing in its way

Researchers review how Food-as-Medicine (FAM) interventions can improve health, reduce healthcare costs, and reshape food production systems. They emphasize the urgent need for clinical validation before scaling individualized nutrition solutions.

8 Apr 2025

Tolebrutinib shows promise for treating non-relapsing secondary progressive multiple sclerosis

A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, a group of drugs originally developed to treat lymphomas and related blood disorders, demonstrated a 31% delay in the onset of six-month confirmed disability progression (CDP) in patients with non-relapsing secondary progressive multiple sclerosis (SPMS).

8 Apr 2025

New discovery promises to revolutionize liver organoid development

Organoids are small-scale models that mimic human organs. These models could help scientists understand diseases and test treatments, and potentially aid in regenerative therapeutic methods.

8 Apr 2025

Lack of ceramides in blood vessels could lead to obesity-related heart diseases

New research from Weill Cornell Medicine has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes-not the presence of certain fats, but their suppression.

8 Apr 2025

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Experimental drug NU-9 - a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) - improves neuron health in animal models of Alzheimer's disease, according to a new Northwestern University study.

8 Apr 2025

Daytime eating could mitigate health risks of night shift work

A study led by researchers at Mass General Brigham suggests that, when it comes to cardiovascular health, food timing could be a bigger risk factor than sleep timing.

8 Apr 2025

Global research initiative aims to optimize post-cardiac arrest ICU care

Researchers at 60 different intensive care units around the world are seeking to establish methods to expedite and improve post-cardiac arrest recovery at ICUs.

8 Apr 2025

Experts warn of rising HIV deaths with planned aid cuts

Global deaths from HIV/AIDS and new infections could soar to levels unseen since the start of the century if planned funding cuts to foreign aid are sustained, undermining years of progress, experts warn.

8 Apr 2025

Cannabis extract can improve behavior of children and teens with autism spectrum disorder

New research presented at the 2025 European Congress of Psychiatry reveals that the use of cannabidiol (CBD) cannabis extract can lead to meaningful benefits and improve the behavior of children and adolescents with autism spectrum disorder (ASD).

8 Apr 2025

Semaglutide linked to higher risk of vision problems, FDA data analysis shows

Researchers from the University of Bern analyzed over 300,000 FDA reports and found semaglutide use was linked to a higher reporting rate of vision impairment. The findings call for further study into the ocular risks of this widely prescribed diabetes and weight loss drug.

8 Apr 2025

Genetic tendency to sedentary behavior linked to higher heart disease risk

Although sedentary behavior may be an evolutionarily selected trait, it is still important to try to be physically active, says a new study conducted at the University of Jyväskylä, Finland.

8 Apr 2025