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Mayo Clinic researchers find new experimental drug that shrinks tumors in multiple myeloma patients

Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma. The findings are published in Nature Medicine.

8 Mar 2017

Newer, more effective medications increase number of patients achieving HCV cure

A new analysis reveals a dramatic transformation in the care of patients infected with hepatitis C virus (HCV) as more effective and tolerable medications have become available.

8 Mar 2017

Major pledge could lead to new treatments for autism

Autism will be better understood thanks to a substantial investment from a US philanthropic foundation to the University of Edinburgh.

7 Mar 2017

Clinical study seeks to examine new combination therapy for treating AML patients

A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.

7 Mar 2017

Scientists establish framework for understanding mechanics that underlie vesicle formation

Engineers at Carnegie Mellon University and biomedical researchers at the University of Pittsburgh and Magee-Womens Research Institute have established a framework for understanding the mechanics that underlie vesicle formation.

7 Mar 2017

Graduate students develop novel microfluidic platform for monitoring single cell-level electroporation

Graduate students Mingde 'Jack' Zheng and Joseph Sherba have developed a novel, microfluidic platform for monitoring electroporation and molecular delivery at the single cell-level as part of a collaborative re-search team led by Professors Jeffrey Zahn and David Shreiber in the Department of Biomedical Engineer-ing and Professors Hao Lin and Jerry Shan in the Department of Mechanical and Aerospace Engineering at Rutgers,

3 Mar 2017

New, low-cost biosimilar for IBD therapy shows efficacy and safety

Treatment of Crohn's disease and ulcerative colitis has been greatly improved by the introduction of biologic therapies such as infliximab (which targets tumour necrosis factor alpha), but at considerable cost.

3 Mar 2017

Study provides insights into how cancer cells can evade FGFR inhibitors

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.

2 Mar 2017

Duke researchers discover potential cause for ALS syndromes using mouse models

A team of researchers at Duke University Medical Center led by Dr. Paulo Ferreira and whose work was supported by the National Institutes of Health has found that derailing the transport of certain receptors that carry cargoes from and to the nucleus of motor neurons causes motor neuron disease in mice.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

UC scientists discover new strategy to personalize blood, brain cancer therapy

Researchers at the University of Cincinnati College of Medicine have discovered a new potential strategy to personalize therapy for brain and blood cancers.

1 Mar 2017

Study suggests new strategy for treating Alzheimer's disease

Alzheimer's disease (AD) is one of the most common form of dementia. In search for new drugs for AD, the research team, led by Professor Mi Hee Lim of Natural Science at UNIST has developed a metal-based substance that works like a pair of genetic scissors to cut out amyloid-β (Aβ), the hallmark protein of AD.

28 Feb 2017

SBP researchers identify new regulator of innate immune response to foreign invaders

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a new regulator of the innate immune response—the immediate, natural immune response to foreign invaders.

28 Feb 2017

$Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus$

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

In a small phase I and II clinical trial, Johns Hopkins researchers and colleagues elsewhere found that the high-fat, low-carbohydrate ketogenic diet was a safe and effective treatment option for the majority of adults experiencing a relatively rare, often fatal and always severe form of epilepsy marked by prolonged seizures that require medically induced comas to prevent them from further damaging the body and the brain.

27 Feb 2017

Incidence of inflammatory bowel disease continues to increase in Denmark, research reveals

New research indicates that the incidence of inflammatory bowel disease-including ulcerative colitis (UC) and Crohn's disease (CD)-in Denmark is on the rise and is among the highest in the world.

23 Feb 2017

Scientists detect antimicrobial protein fragments in Komodo dragon’s blood

In a land where survival is precarious, Komodo dragons thrive despite being exposed to scads of bacteria that would kill less hardy creatures.

22 Feb 2017

New portable device may hold key to accurately detecting Zika virus

About the size of a tablet, a portable device that could be used in a host of environments like a busy airport or even a remote location in South America, may hold the key to detecting the dreaded Zika virus accurately, rapidly and inexpensively using just a saliva sample.

22 Feb 2017

Essen Bioscience to Showcase IncuCyte® Live-cell Analysis System and Applications at AACR, Booth #1365

The IncuCyte® live-cell analysis platform from Essen BioScience will be showcased at the upcoming AACR conference, booth #1365.

From Sartorius 22 Feb 2017

Research on repair of broken hearts hints at possibility of new designer cardiovascular therapies

Unlike the self-repair abilities of our skin, bone and other tissues, which can readily heal and rebuild themselves after injury, evolution has left the mammalian heart with relatively little regenerative capacity.

22 Feb 2017

RCSI research focuses on need to personalise treatment for bowel cancer patients

Researchers in RCSI (Royal College of Surgeons in Ireland) have conducted further in-depth research to predict how patients with bowel (colorectal) cancer will respond effectively to chemotherapy, to ensure that patients will get the most suitable type of treatment from the outset.

21 Feb 2017

Therapeutics News and Research

Mayo Clinic researchers find new experimental drug that shrinks tumors in multiple myeloma patients

Newer, more effective medications increase number of patients achieving HCV cure

Major pledge could lead to new treatments for autism

Clinical study seeks to examine new combination therapy for treating AML patients

Scientists establish framework for understanding mechanics that underlie vesicle formation

Graduate students develop novel microfluidic platform for monitoring single cell-level electroporation

New, low-cost biosimilar for IBD therapy shows efficacy and safety

Study provides insights into how cancer cells can evade FGFR inhibitors

Duke researchers discover potential cause for ALS syndromes using mouse models

Using Spherical Nucleic Acids to Track and Treat Disease

UC scientists discover new strategy to personalize blood, brain cancer therapy

Study suggests new strategy for treating Alzheimer's disease

SBP researchers identify new regulator of innate immune response to foreign invaders

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

Incidence of inflammatory bowel disease continues to increase in Denmark, research reveals

Scientists detect antimicrobial protein fragments in Komodo dragon’s blood

New portable device may hold key to accurately detecting Zika virus

Essen Bioscience to Showcase IncuCyte® Live-cell Analysis System and Applications at AACR, Booth #1365

Research on repair of broken hearts hints at possibility of new designer cardiovascular therapies

RCSI research focuses on need to personalise treatment for bowel cancer patients

Next-generation therapeutics eBook eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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