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MYC proteins form hollow spheres that shield the genome of cancer cells

MYC genes and their proteins play a central role in the emergence and development of almost all cancers. They drive the uncontrolled growth and altered metabolism of tumour cells. And they help tumours hide from the immune system.

23 Nov 2022

Study reveals structural insights into the elusive tankyrase protein that fuels bowel cancer

Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes – potentially paving the way for better and less toxic cancer drugs.

23 Nov 2022

Researchers make an incredible discovery about mammalian brains

In a new breakthrough to understand more about the mammalian brain, University of Copenhagen researchers have made an incredible discovery.

23 Nov 2022

Single drug compound may offer a promising new strategy for treating prostate cancer patients

A single drug compound simultaneously attacks hard-to-treat prostate cancer on several fronts, according to a new study in mice and human cells.

23 Nov 2022

CAR T therapy extends its reach beyond oncology

Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers.

23 Nov 2022

A simple method to prepare carbon isotope-labeled versions of drugs and diagnostics

Dr. Benjamin Rotstein and collaborators unveil an operationally simple method to prepare carbon isotope-labeled versions of drugs and diagnostics.

22 Nov 2022

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Gene therapies can treat, even potentially cure, certain genetic diseases, but it is challenging to deliver the treatments to the parts of the body where they are needed.

22 Nov 2022

People having trouble sleeping should try exercise, study suggests

The vast majority of people have trouble sleeping from time to time. However, 10 to 20 per cent of the population struggle more than the rest of us and have serious long-term sleep problems.

22 Nov 2022

Discovery could lead to new mantle cell lymphoma drugs

A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma in preclinical tests, according to a study from Weill Cornell Medicine researchers.

22 Nov 2022

New EULAR recommendations for screening and treating infections in AIIRD patients

It is already known that people who are immunocompromised are more prone to infections. Chronic and opportunistic infections are often found in people with an AIIRD, and may be linked to some of the immunosuppressive and immunomodulatory treatments used to treat these rheumatic diseases.

22 Nov 2022

Diastolic blood pressure found to be associated with neuroticism

Diastolic blood pressure - the lower of the two numbers in a blood pressure reading - is highly likely to cause neurotic personality trait, finds research published in the open access journal General Psychiatry.

22 Nov 2022

Acupuncture significantly improves lower back or pelvic pain during pregnancy

Acupuncture can significantly relieve the lower back and/or pelvic pain frequently experienced by women during their pregnancy, suggests a pooled data analysis of the available evidence, published in the open access journal BMJ Open.

22 Nov 2022

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Cancer Research UK’s newly launched innovation engine, Cancer Research Horizons, and Newcastle University, have announced a further significant extension of their strategic drug discovery alliance with Astex Pharmaceuticals (UK) (‘Astex’), a biotechnology company dedicated to the discovery and development of novel small molecule therapeutics.

22 Nov 2022

Treating long covid is rife with guesswork

Medical equipment is still strewn around the house of Rick Lucas, 62, nearly two years after he came home from the hospital. He picks up a spirometer, a device that measures lung capacity, and takes a deep breath — though not as deep as he'd like.

22 Nov 2022

Schools, sheriffs, and syringes: State plans vary for spending $26B in opioid settlement funds

With more than 200 Americans still dying of drug overdoses each day, states are beginning the high-stakes task of deciding how to spend billions of dollars in settlement funds from opioid manufacturers and distributors.

22 Nov 2022

Exploring antibiotic resistance in the EU

Antibiotic resistance is one of the greatest threats to global human health and to development.

22 Nov 2022

The vaginal microbiome through the lens of systems biology

A new paper recently published online in Trends in Microbiology journal reviews the systems biology approach to explore the vaginal microbiome (VMB), helping to understand its composition and function and the mechanisms by which it interacts with the host.

22 Nov 2022

Drugs News and Research

MYC proteins form hollow spheres that shield the genome of cancer cells

Study reveals structural insights into the elusive tankyrase protein that fuels bowel cancer

Researchers make an incredible discovery about mammalian brains

Single drug compound may offer a promising new strategy for treating prostate cancer patients

CAR T therapy extends its reach beyond oncology

A simple method to prepare carbon isotope-labeled versions of drugs and diagnostics

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

People having trouble sleeping should try exercise, study suggests

Discovery could lead to new mantle cell lymphoma drugs

New EULAR recommendations for screening and treating infections in AIIRD patients

Diastolic blood pressure found to be associated with neuroticism

Acupuncture significantly improves lower back or pelvic pain during pregnancy

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Treating long covid is rife with guesswork

Schools, sheriffs, and syringes: State plans vary for spending $26B in opioid settlement funds

Exploring antibiotic resistance in the EU

The vaginal microbiome through the lens of systems biology

Using induced pluripotent stem cells to recreate the adrenal gland in a petri dish

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

Researchers identify best methods to study resting state of the brain in marmosets

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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