Efficacy News and Research

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REAER is a promising therapy for improving the lives of people with multiple sclerosis

A team of multiple sclerosis (MS) experts at Kessler Foundation led the first pilot randomized controlled trial of robotic-exoskeleton assisted exercise rehabilitation (REAER) effects on mobility, cognition, and brain connectivity in people with substantial MS-related disability.

29 May 2021

New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

A new study, published in Nano Letters, describes an effective new COVID-19 vaccine candidate based on a messenger ribonucleic acid (mRNA) platform.

28 May 2021

Glycosylation a significant element in SARS-CoV-2 infection and vaccine design, says study

A new study by researchers from Taiwan and the US suggests that the removal of unnecessary glycans from spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposes highly conserved sequences and opens the door for the development of broadly protective vaccines against the virus and its variants.

28 May 2021

Study supports single-dose COVID-19 vaccine strategy for previously infected individuals

Researchers in the Netherlands have provided evidence that a single dose of Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine is sufficient to protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among people who have already been infected with the virus.

28 May 2021

COLCORONA study shows that colchicine can reduce complications in certain COVID-19 patients

The Montreal Heart Institute announces that the COLCORONA study results are published today in The Lancet Respiratory Medicine.

28 May 2021

Melatonin prevents kidney damage caused by metabolic complications of obesity

Scientists from the University of Granada (UGR), the Hospital Universitario La Paz (Madrid), and the University of Texas (USA) have taken an important step in the fight against kidney damage and its progression towards kidney failure, which is closely related to diabesity (obesity and its type 2 diabetes) and its complications.

27 May 2021

Researchers develop “cell encapsulation” technology to stimulate immunity to fight cancer

Immunotherapy techniques developed in oncology to combat cancerous cells have great potential for fighting viruses.

27 May 2021

Could the marine compound plitidepsin promote recovery from moderate COVID-19?

A new paper by an international team of researchers describes experimental evidence of the antiviral efficacy of a marine compound called plitidepsin against SARS-CoV-2. The findings show that plitidepsin inhibits SARS-CoV at low concentrations, as observed by a thousand-fold reduction in genomic RNA and viral titers in cells exposed to the virus in culture when treated.

27 May 2021

Nanobody inhalation found to be effective against COVID-19 in hamsters

In a recent paper, researchers describe an aerosolized nanobody formulation that was found to effectively block SARS-CoV-2 in Syrian hamsters.

27 May 2021

New DNA COVID-19 vaccine proven effective in mice

A new study has shown that a new DNA-based COVID-19 vaccine successfully induced immunization against SARS-CoV-2 in mice and hamsters.

27 May 2021

Lifting FDA restrictions on mifepristone could normalize medication abortion

In a new study published online in spring 2021 and in the July issue of the journal Contraception, University of Chicago Medicine investigators and colleagues interviewed primary care providers in Illinois about their interest in providing medication abortion care and found that lifting FDA restrictions on mifepristone to allow pharmacy dispensing could normalize medication abortion, facilitate its use in primary care facilities, and address disparities in reproductive health access.

27 May 2021

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

COVID-19 was initially described as lung inflammation, or pneumonia, in older adults. However, we now know that SARS-CoV-2 infections can cause a wide range of symptoms in people of all ages, ranging from no symptoms at all to systemic inflammation and even death.

27 May 2021

New porous biomaterial could help in bone repair

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new biomaterial made entirely from discarded bullfrog skin and fish scales that could help in bone repair.

27 May 2021

Disproportionate number of SARS-CoV-2 breakthrough infections are caused by variants of concern

A study conducted by researchers in the United States has shown that among twenty patients with breakthrough infection following vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – all of the infections were caused by variants of concerns.

26 May 2021

New article sheds more light on myopia control efficacy

A new paper that has been accepted for publication in Ophthalmic & Physiological Optics, the peer-reviewed journal of The College of Optometrists (UK), furthers understanding of myopia control efficacy in the context of normal childhood eye growth. Axial Length Targets for Myopia Control (Chamberlain P, et al.) is now available online via Open Access.

26 May 2021

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

The National Institute on Aging (NIA), part of the National Institutes of Health, has awarded a $5 million grant to researchers at University of California San Diego School of Medicine to conduct a first-in-human Phase 1 clinical trial of a gene therapy for treating Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

26 May 2021

Researchers synthesize potential drugs with anti-cancer effects

New effective compounds, which can be endogenous donors of a signaling molecule - hydrogen sulfide in the body, were synthesized by SUSU scientists. Due to this property, the obtained compounds are potential drugs with a cancer-preventing effect.

26 May 2021

Previous H3N2 influenza A infection may explain some cases of severe COVID-19

According to research from the University of California, some cases of severe coronavirus disease 2019 (COVID-19) may be related to the immunological memory of previous H3N2 influenza A infection.

26 May 2021

Study shows how rare but serious post-COVID-19 complication develops in children, adolescents

A multidisciplinary team from MassGeneral Hospital for Children (MGHfC), Brigham and Women's Hospital and other institutions have identified the mechanism of how an extremely rare but serious post-COVID-19 complication develops in children and adolescents.

26 May 2021

Moderna's COVID vaccine proves effective against South African variant in primates

Researchers in the United States have demonstrated the efficacy of Moderna’s coronavirus disease 2019 (COVID-19) vaccine at protecting against the South African B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in non-human primates.

26 May 2021

Efficacy News and Research

REAER is a promising therapy for improving the lives of people with multiple sclerosis

New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

Glycosylation a significant element in SARS-CoV-2 infection and vaccine design, says study

Study supports single-dose COVID-19 vaccine strategy for previously infected individuals

COLCORONA study shows that colchicine can reduce complications in certain COVID-19 patients

Melatonin prevents kidney damage caused by metabolic complications of obesity

Researchers develop “cell encapsulation” technology to stimulate immunity to fight cancer

Could the marine compound plitidepsin promote recovery from moderate COVID-19?

Nanobody inhalation found to be effective against COVID-19 in hamsters

New DNA COVID-19 vaccine proven effective in mice

Lifting FDA restrictions on mifepristone could normalize medication abortion

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

New porous biomaterial could help in bone repair

Disproportionate number of SARS-CoV-2 breakthrough infections are caused by variants of concern

New article sheds more light on myopia control efficacy

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

Researchers synthesize potential drugs with anti-cancer effects

Previous H3N2 influenza A infection may explain some cases of severe COVID-19

Study shows how rare but serious post-COVID-19 complication develops in children, adolescents

Moderna's COVID vaccine proves effective against South African variant in primates

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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