Infectious Diseases News and Research

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Shire and Sangamo revise agreement to expedite development of ZFP Therapeutics for Huntington's disease, hemophilia A and B

Sangamo BioSciences, Inc., a leader in therapeutic genome editing, announced today that the company and its collaborator, Shire plc, have agreed to revise their January 2012 collaboration and license agreement to expedite the development of ZFP Therapeutics for hemophilia A and B and Huntington's disease.

2 Sep 2015

Ascletis completes US$35 million (RMB 220 million) financing

Ascletis announced today the completion of a US$35 million (RMB 220 million) financing. The investment was led by C-Bridge Capital, joined by Tasly Pharmaceutical and Singapore-based Pavilion Capital. The valuation of the Company before financing was US$300 million.

2 Sep 2015

UC San Diego-led research team awarded $1.89 million to carry out research on leptospirosis

An international research team, headed by Joseph Vinetz, MD, professor of medicine at University of California, San Diego School of Medicine and director of the UC San Diego Center for Tropical Medicine and Travelers Health, has been awarded a 5-year, $1.89 million cooperative agreement to carry out translational research studies of leptospirosis, an infectious and sometimes fatal bacterial disease endemic in much of the world.

2 Sep 2015

Volatile anesthetics may combat viral and bacterial infections in the lung

In use for more than a century, inhaled anesthetics like nitrous oxide and halothane have made modern surgery possible. Now, in experiments in mice, researchers at Johns Hopkins and elsewhere have added to evidence that certain so-called "volatile" anesthetics -- commonly used during surgeries -- may also possess powerful effects on the immune system that can combat viral and bacterial infections in the lung, including influenza and pneumonia.

2 Sep 2015

ACP urges health professionals to speak out on mass deportation of immigrants

The American College of Physicians (ACP) today called on physicians, individually and collectively, to speak out against proposals to deport the 12 million U.S. residents who lack documentation of legal residency status, citing the adverse impact that mass deportation would have on individual and the health of the public.

2 Sep 2015

SLU scientist receives grant to solve blood-clotting mysteries

Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a "linker" region that may be the key to developing better life-saving drugs.

1 Sep 2015

Janssen, Bayer HealthCare announce results from landmark studies evaluating safety profile of XARELTO in NVAF patients

Janssen Pharmaceuticals, Inc., and its development partner, Bayer HealthCare, today announced results from PMSS (Post-Marketing Safety Surveillance) and XANTUS (XARELTO for Prevention of Stroke in Patients with Atrial Fibrillation), their landmark real-world studies evaluating the safety of XARELTO in people with non-valvular atrial fibrillation (NVAF).

1 Sep 2015

Sleep loss increases chance of catching a cold

A new study led by a UC San Francisco sleep researcher supports what parents have been saying for centuries: to avoid getting sick, be sure to get enough sleep.

1 Sep 2015

New $6.25 million NIH grant to help investigators launch research center to slow and stop HIV

A new five-year, $6.25 million grant from the National Institutes of Health will help investigators from Northwestern University, the University of Chicago and others across the city of Chicago work together to slow and stop HIV.

1 Sep 2015

Multiple HIV-1 variants at the beginning of infection impact viral load setpoints

HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to a paper published today in the journal Nature Medicine.

1 Sep 2015

Soligenix completes enrolment in SGX942 Phase 2 trial for oral mucositis in cancer patients

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today it has completed enrollment of the additional subjects, as directed by the Data Review Committee (DRC) earlier this year, into the company's Phase 2 study for SGX942.

31 Aug 2015

Ascletis receives TFDA approval to begin Phase II trial of interferon-free HCV regimen

Ascletis today announced it received the approval from the Taiwan Food and Drug Administration (TFDA) to start phase II clinical trial for its all-oral interferon (IFN)-free regimen to treat chronic hepatitis C (CHC).

31 Aug 2015

Scientists discover the oldest case of leukemia in prehistoric female skeleton

Scientists of the Senckenberg Center for Human Evolution and Paleoenvironment and the University of Tübingen have discovered what may well be the oldest known case of Leukemia.

31 Aug 2015

New ESC Guidelines on infective endocarditis support role of imaging in diagnosis

ESC Guidelines published today on infective endocarditis boost the role of imaging in diagnosis of this deadly disease.

29 Aug 2015

National award presented to seven community health centers for innovation in diabetes care

BD, Direct Relief, and the National Association of Community Health Centers (NACHC) honored seven of the nation's 1,200 community health centers with the Innovations in Care Award at this week's Community Health Institute and EXPO in Orlando, Florida.

28 Aug 2015

Cell-to-cell transmission of HIV leads to development of AIDS

Researchers from the Gladstone Institutes have revealed that HIV does not cause AIDS by the virus's direct effect on the host's immune cells, but rather through the cells' lethal influence on one another.

28 Aug 2015

Probiotics show no benefit in preventing gastrointestinal colonization with drug-resistant microbes in ICU patients

Compared with routine medical care, probiotics administered to critically ill patients in intensive care units showed no benefit in preventing the colonization of drug-resistant microbes in the intestinal tract, according to new research at Washington University School of Medicine in St. Louis.

28 Aug 2015

Discovery could help in development of novel cancer-selective viral therapies

Every organism--from a seedling to a president--must protect its DNA at all costs, but precisely how a cell distinguishes between damage to its own DNA and the foreign DNA of an invading virus has remained a mystery.

27 Aug 2015

Soligenix obtains additional funding from NIAID to advance development of OrbeShield for GI ARS treatment

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today that the National Institute of Allergy and Infectious Diseases has exercised its option to advance preclinical development of OrbeShield (oral beclomethasone 17,21-dipropionate or oral BDP).

27 Aug 2015

University of Nottingham to lead £6.5m research project that aims to develop next generation biomaterials

The University of Nottingham is to lead a £6.5m research project which aims to make the leap from 2D to 3D in the development of advanced materials and realise the true potential of regenerative medicine and medical devices for the future.

27 Aug 2015

Infectious Diseases News and Research

Shire and Sangamo revise agreement to expedite development of ZFP Therapeutics for Huntington's disease, hemophilia A and B

Ascletis completes US$35 million (RMB 220 million) financing

UC San Diego-led research team awarded $1.89 million to carry out research on leptospirosis

Volatile anesthetics may combat viral and bacterial infections in the lung

ACP urges health professionals to speak out on mass deportation of immigrants

SLU scientist receives grant to solve blood-clotting mysteries

Janssen, Bayer HealthCare announce results from landmark studies evaluating safety profile of XARELTO in NVAF patients

Sleep loss increases chance of catching a cold

New $6.25 million NIH grant to help investigators launch research center to slow and stop HIV

Multiple HIV-1 variants at the beginning of infection impact viral load setpoints

Soligenix completes enrolment in SGX942 Phase 2 trial for oral mucositis in cancer patients

Ascletis receives TFDA approval to begin Phase II trial of interferon-free HCV regimen

Scientists discover the oldest case of leukemia in prehistoric female skeleton

New ESC Guidelines on infective endocarditis support role of imaging in diagnosis

National award presented to seven community health centers for innovation in diabetes care

Cell-to-cell transmission of HIV leads to development of AIDS

Probiotics show no benefit in preventing gastrointestinal colonization with drug-resistant microbes in ICU patients

Discovery could help in development of novel cancer-selective viral therapies

Soligenix obtains additional funding from NIAID to advance development of OrbeShield for GI ARS treatment

University of Nottingham to lead £6.5m research project that aims to develop next generation biomaterials

eBook: Advancing infectious disease vaccine development eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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