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Promising new drug may offer effective treatment for heart failure patients

Heart failure patients who are getting by on existing drug therapies can look forward to a far more effective medicine in the next five years or so, thanks to University of Alberta researchers.

8 Mar 2017

Penn researchers identify genome-wide changes caused by high-fat diet

By comparing two strains of mice -- one that becomes obese and diabetic on a high-fat diet and another resistant to a high-fat regimen -- researchers from the Perelman School of Medicine at the University of Pennsylvania identified genome-wide changes caused by a high-fat diet.

8 Mar 2017

Bruker showcases innovative high-performance systems and high-value analytical solutions at Pittcon 2017

Bruker (NASDAQ: BRKR) is showcasing a selection of innovative high-performance systems and high-value analytical solutions at Pittcon 2017 (www.pittcon.org), with an emphasis on pharma and applied markets, as well as on nano-materials research and microscopy.

From Bruker BioSpin Group 7 Mar 2017

Resveratrol helps protect neuromuscular junctions from negative effects of aging, study shows

Scientists have discovered that resveratrol, a compound in the skin of red grapes and red wine, and metformin, a drug often prescribed to fight type 2 diabetes, have many of the neuroprotective benefits of a low-calorie diet and exercise.

7 Mar 2017

Deep learning transforms the drug discovery process in collaboration between Insilico Medicine and Life Extension

In March 2016 Insilico Medicine initiated a research collaboration with Life Extension to apply advanced bioinformatic methods and deep learning algorithms to screen for naturally occurring compounds that may slow down or even reverse the cellular and molecular mechanisms of aging. Today Life Extension (LE) launched a new line of nutraceuticals called GEROPROTECTTM, and the first product in the series called Ageless CellTM combines some of the natural compounds that were shortlisted by Insilico Medicine’s algorithms and are generally recognized as safe (GRAS).

7 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

TSRI scientists discover how key protein establishes proper vision

Scientists from the Florida campus of The Scripps Research Institute have discovered how a protein called α2δ4 establishes proper vision.

6 Mar 2017

Researchers uncover new genetic clues linked to autoimmune kidney disease

Researchers have uncovered new genetic clues to understanding IgA nephropathy (IgAN), or Berger's disease, an autoimmune kidney disease and a common cause of kidney failure.

6 Mar 2017

McMaster researchers find new way to combat world's worst infectious diseases

McMaster University researchers have found a new way to treat the world's worst infectious diseases, the superbugs that are resistant to all known antibiotics.

6 Mar 2017

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

Two weeks of voluntary wheel running induces higher expression of irisin--a fat-burning hormone that is released during exercise--in bone tissue in mice.

3 Mar 2017

Researchers discover new way to develop painkillers without harmful side effects

Researchers from Charité - Universitätsmedizin Berlin have discovered a new way of developing painkillers.

3 Mar 2017

Notch activity of cells in tumor microenvironment can influence cancer metastases, study shows

Blood vessels play a critical role in the growth and spread of cancer. The cells lining the inner wall of blood vessels (endothelial cells) and cancer cells are in close contact to each other and mutually influence each other.

3 Mar 2017

HORIBA Scientific honors Dr. Ibrahim Cissé with Young Fluorescence Investigator Award

HORIBA Scientific, world leader in fluorescence spectroscopy systems, awarded Dr. Ibrahim Cissé, the class of 1922 Assistant Professor of Physics at MIT, its annual Young Fluorescence Investigator Award. HORIBA Scientific has been the sole sponsor of this award since 1997.

3 Mar 2017

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery.

3 Mar 2017

Blocking protein found on surface of ovarian cancer cells could prevent metastasis, research suggests

Blocking a protein found on the surface of ovarian cancer cells could prevent or reduce the spread of the disease to other organs, according to new research at the University of Illinois at Chicago.

3 Mar 2017

Scientists use molecular bait strategy to capture and isolate cancer-prone protein

Scientists from the Center for Self-assembly and Complexity (CSC) successfully isolated a cancer-prone protein by fishing out the proteins using 'molecular bait'.

2 Mar 2017

Cigarette smoke blocks lung's self-healing that can lead to COPD

Smoke from cigarettes blocks self-healing processes in the lungs and consequently can lead to chronic obstructive pulmonary disease (COPD).

2 Mar 2017

Cholesterol-processing enzyme could be therapeutic target to stave off neurologic diseases

An enzyme that helps break down cholesterol may also be a therapeutic target to stave off neurologic diseases, including Alzheimer's and a rare genetic disorder, according to a new study published in the Journal of Biological Chemistry.

2 Mar 2017

Research may offer brand-new tool for early diagnosis for lethal melanomas

Melanoma is the deadliest form of skin cancer, with over 232,000 new cases and 55,000 deaths per year worldwide.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

Molecule News and Research

Promising new drug may offer effective treatment for heart failure patients

Penn researchers identify genome-wide changes caused by high-fat diet

Bruker showcases innovative high-performance systems and high-value analytical solutions at Pittcon 2017

Resveratrol helps protect neuromuscular junctions from negative effects of aging, study shows

Deep learning transforms the drug discovery process in collaboration between Insilico Medicine and Life Extension

New drug-like compound shows potential to treat symptoms of lupus

TSRI scientists discover how key protein establishes proper vision

Researchers uncover new genetic clues linked to autoimmune kidney disease

McMaster researchers find new way to combat world's worst infectious diseases

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

Researchers discover new way to develop painkillers without harmful side effects

Notch activity of cells in tumor microenvironment can influence cancer metastases, study shows

HORIBA Scientific honors Dr. Ibrahim Cissé with Young Fluorescence Investigator Award

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

Blocking protein found on surface of ovarian cancer cells could prevent metastasis, research suggests

Scientists use molecular bait strategy to capture and isolate cancer-prone protein

Cigarette smoke blocks lung's self-healing that can lead to COPD

Cholesterol-processing enzyme could be therapeutic target to stave off neurologic diseases

Research may offer brand-new tool for early diagnosis for lethal melanomas

Using Spherical Nucleic Acids to Track and Treat Disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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