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Study provides new insights into side effects of antipsychotics

After much deliberation and anxiety, the family finally sought psychiatric help for their son. And the results were in a way, a relief.

28 Feb 2017

Scientists discover how genetic mutation disarms tumor-suppressing BRCA1 proteins in breast cancer

Of the more than 3 million people with breast cancer in the United Stated, about 10 percent carry an inherited mutation in their BRCA1 gene. In health, the gene is responsible for suppressing tumors. In disease, the gene goes terribly awry.

28 Feb 2017

MIT biological engineers develop method to measure heme levels inside malaria parasite

The iron-containing molecule heme is necessary for life. Cells require heme to perform the chemical reactions that produce energy, among other critical tasks.

28 Feb 2017

Yale researchers explore how aggressive LUAD cells manage to grow outside the lungs

More people die of lung cancer each year than breast, colon, and prostate cancers combined. One particularly lethal form of the disease is lung adenocarcinoma or LUAD, which afflicts both smokers and non-smokers.

28 Feb 2017

Researchers to examine link between zinc deficiency, Hedgehog, and prostate cancer

Experiments show that Hedgehog signaling - a chain of molecular events critical in embryonic development - creates conditions beneficial to the unregulated cell growth associated with cancer in adults.

28 Feb 2017

New anti-cocaine monoclonal antibody moves forward towards clinical studies in humans

A University of Cincinnati researcher who has developed an immunotherapy to help reverse cocaine addiction that's been successful in animal models says he hopes to have it in clinical trials in human volunteers within a year.

28 Feb 2017

New molecule may inhibit growth of aggressive pediatric brain tumor

Northwestern Medicine scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor. The tumor is always fatal and primarily strikes children under 10 years old.

27 Feb 2017

Researchers aim to develop sustained and controllable insulin release system for treatment of diabetes

The prevalence of diabetes has grown around the world over the past three decades. In 2016, the World Health Organization estimated that 422 million people had the disease as the rate of obesity also increased.

27 Feb 2017

$Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus$

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

In a small phase I and II clinical trial, Johns Hopkins researchers and colleagues elsewhere found that the high-fat, low-carbohydrate ketogenic diet was a safe and effective treatment option for the majority of adults experiencing a relatively rare, often fatal and always severe form of epilepsy marked by prolonged seizures that require medically induced comas to prevent them from further damaging the body and the brain.

27 Feb 2017

Huddersfield researchers discover cancer curing molecule that opens door for highly-effective treatment

SCIENTISTS at the University of Huddersfield are the first to arrive at a deep understanding of a molecule that destroys cancerous tumours without harming healthy cell tissue.

27 Feb 2017

Researchers shed new light on molecular pump that ejects anticancer agents

Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. Researchers at The Rockefeller University have shed new light on a molecular pump that makes this possible, by determining its three-dimensional structure, down to the level of atoms.

25 Feb 2017

Researchers discover promising target for treatment of leishmaniasis

Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.

24 Feb 2017

New research offers insights into how differences arise in common illnesses

As much as we try to avoid it, we are constantly sharing germs with those around us. But even when two people have the same infection, the resulting illnesses can be dramatically different--mild for one person, severe or even life-threatening for the other.

24 Feb 2017

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Current treatments for rheumatoid arthritis relieve the inflammation that leads to joint destruction, but the immunologic defect that triggers the inflammation persists to cause relapses, according to research conducted at NYU Langone Medical Center and the University of Pittsburgh.

24 Feb 2017

Researchers reveal biological pathways involved in diabetic kidney disease

Diabetes is a leading cause of kidney disease, a serious, often fatal complication that is difficult to diagnose in early, potentially treatable stages.

24 Feb 2017

Cocaine use by fathers may negatively impact cognitive development in male offspring

Fathers who use cocaine at the time of conceiving a child may be putting their sons at risk of learning disabilities and memory loss.

24 Feb 2017

Scientists propose potential new treatment for Gaucher disease

Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than current therapies.

23 Feb 2017

Precise inactivation of neurotransmitter receptors using CALI technique erases fear memory in mice

The delivery of chemical messenger (neurotransmitter) receptors to the junctions between nerve cells (synapses) is crucial to cognitive processes such as memory.

23 Feb 2017

Study provides new insights into molecular mechanisms behind short-term neuronal plasticity

In a study published in Cell Reports in February 2017, Matt Rowan, Ph.D., a Post-doctoral researcher in the lab of Dr. Jason Christie, sought to understand the molecular mechanisms behind a type of short-term neuronal plasticity that may have importance for motor control.

23 Feb 2017

Scientists discover potent trigger of inflammatory disease

Institute scientists have revealed a potent inflammatory molecule released by dying cells triggers inflammation during necroptosis, a recently described form of cell death linked to inflammatory disease.

22 Feb 2017

Molecule News and Research

Study provides new insights into side effects of antipsychotics

Scientists discover how genetic mutation disarms tumor-suppressing BRCA1 proteins in breast cancer

MIT biological engineers develop method to measure heme levels inside malaria parasite

Yale researchers explore how aggressive LUAD cells manage to grow outside the lungs

Researchers to examine link between zinc deficiency, Hedgehog, and prostate cancer

New anti-cocaine monoclonal antibody moves forward towards clinical studies in humans

New molecule may inhibit growth of aggressive pediatric brain tumor

Researchers aim to develop sustained and controllable insulin release system for treatment of diabetes

Study finds ketogenic diet as 'feasible' option for people with super-refractory status epilepticus

Huddersfield researchers discover cancer curing molecule that opens door for highly-effective treatment

Researchers shed new light on molecular pump that ejects anticancer agents

Researchers discover promising target for treatment of leishmaniasis

New research offers insights into how differences arise in common illnesses

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Researchers reveal biological pathways involved in diabetic kidney disease

Cocaine use by fathers may negatively impact cognitive development in male offspring

Scientists propose potential new treatment for Gaucher disease

Precise inactivation of neurotransmitter receptors using CALI technique erases fear memory in mice

Study provides new insights into molecular mechanisms behind short-term neuronal plasticity

Scientists discover potent trigger of inflammatory disease

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Evaluating new approaches for rare disease genomics

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