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MHRA authorizes the COVID-19 vaccine developed by Sanofi

VidPrevtyn Beta, the COVID-19 vaccine developed by Sanofi, has been authorised by the Medicines and Healthcare products Regulatory Agency (MHRA).

21 Dec 2022

Study reveals both dark adapted and light-activated structures of a phytochrome

Scientist have revealed both dark adapted and light-activated structures of a red photosensory protein, phytochrome.

20 Dec 2022

New method combines injectable radioactive gel with systemic chemotherapy to treat pancreatic cancer

Pancreatic cancer is one of the deadliest types of cancer - in the U.S., it is estimated that over 88 percent of people will die from the disease within five years of their diagnosis.

20 Dec 2022

COVID-19 epidemiology can be estimated using blood donation samples

An article published in the journal eLife reports a study in which researchers concluded that the proportion of the population previously infected by SARS-CoV-2 (infection-induced seroprevalence) can be estimated using blood donation samples.

20 Dec 2022

Study finds several flavor/fragrance compositions that inhibit vRBD-hACE2 binding

A study describes the antiviral activity of flavor/fragrance compositions against SARS-CoV-2.

20 Dec 2022

Research uncovers a new way to boost the effectiveness of RNA therapies

Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells - cells that control your heartbeat - can "fight back" against therapies to biologically correct abnormal heartbeat rates.

20 Dec 2022

Phenotypic plasticity may allow cancer cells to evade standard therapy

Glioblastomas (GBMs) are incurable brain tumors with a prognosis of about one-and-a half years on average. They are highly resistant to treatment and have defied all attempts at precision therapy.

20 Dec 2022

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Researchers examined the pathological impacts of the structural components of SARS-CoV-2 on human periodontal cells and tissue to understand the association between coronavirus disease 2019 (COVID-19) and deteriorating oral health.

20 Dec 2022

Seroprevalence measurements reveal a higher incidence of asymptomatic SARS-CoV-2 infections among residents of three federal German states

Researchers measured the seroprevalence against SARS-CoV-2 in blood donors from the states of Hesse, Lower Saxony, and North Rhine-Westphalia in Germany to determine the incidence of undetected asymptomatic SARS-CoV-2 infections.

20 Dec 2022

Researchers generate a remodeled live-attenuated measles vaccine capable of driving nAb responses against SARS-CoV-2 spike protein

Researchers developed a measles virus (MeV)-vectored vaccine capable of inducing high neutralizing antibody (nAb) responses against SARS-CoV-2.

20 Dec 2022

What is the impact of cholesterol on SARS-CoV-2 Spike protein-mediated membrane fusion?

Researchers assessed the impact of ceramide (CER) and cholesterol (CHOL) on membrane fusion mediated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

20 Dec 2022

The effectiveness of a bivalent COVID-19 mRNA booster dose against hospitalization

Researchers reported on the vaccine effectiveness of a bivalent vaccine booster administered after ≥2.0 doses of monovalent mRNA vaccines against COVID-19–related hospitalizations among adult individuals 65.0 years or older.

20 Dec 2022

Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

Researchers described four novel monoclonal antibodies with potent and broad neutralization activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the current globally dominant Omicron BA.4/BA.5.

20 Dec 2022

Newly designed antibiotic effective against multidrug-resistant bacteria

Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.

20 Dec 2022

Smart molecular glue ensures the nucleus is correctly positioned for cell division

Researchers from Paul Scherrer Institute PSI and ETH Zurich have discovered how proteins in the cell can form tiny liquid droplets that act as a smart molecular glue.

19 Dec 2022

Immune-evading Mycobacterium tuberculosis prevents inflammatory responses by hijacking the host’s ubiquitin

A new study discussed the findings of Chai et al., which revealed that triple specificity protein phosphatase (ptpB) secreted by Mycobacterium tuberculosis inhibits pyroptosis and the release of cytokines by macrophages, allowing M. tuberculosis to invade the immune system.

19 Dec 2022

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Researchers at Memorial Sloan Kettering Cancer Center (MSKCC) in New York have discovered that common cancer treatments, such as radiotherapy or anthracycline drugs, cause long-term damage to heart tissue by activating a key inflammatory signaling pathway.

19 Dec 2022

Protein C News and Research

MHRA authorizes the COVID-19 vaccine developed by Sanofi

Study reveals both dark adapted and light-activated structures of a phytochrome

New method combines injectable radioactive gel with systemic chemotherapy to treat pancreatic cancer

COVID-19 epidemiology can be estimated using blood donation samples

Study finds several flavor/fragrance compositions that inhibit vRBD-hACE2 binding

Research uncovers a new way to boost the effectiveness of RNA therapies

Phenotypic plasticity may allow cancer cells to evade standard therapy

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Seroprevalence measurements reveal a higher incidence of asymptomatic SARS-CoV-2 infections among residents of three federal German states

Researchers generate a remodeled live-attenuated measles vaccine capable of driving nAb responses against SARS-CoV-2 spike protein

What is the impact of cholesterol on SARS-CoV-2 Spike protein-mediated membrane fusion?

The effectiveness of a bivalent COVID-19 mRNA booster dose against hospitalization

Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

Newly designed antibiotic effective against multidrug-resistant bacteria

Smart molecular glue ensures the nucleus is correctly positioned for cell division

Immune-evading Mycobacterium tuberculosis prevents inflammatory responses by hijacking the host’s ubiquitin

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Milk antibodies against SARS-CoV-2 after booster vaccination and breakthrough infection

Decoding nucleic acid-based drugs and vaccines through SEC-SLS analysis

Study demonstrates robust antibody response elicited by trivalent protein subunit vaccine against SARS-CoV-2

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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