Therapeutics News and Research

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Study shows involvement of lipid metabolism in tumour metastasis

A study headed by Salvador Aznar Benitah, ICREA researcher at the Institute for Research in Biomedicine, and published today in Nature identifies metastasis-initiating cells through a specific marker, namely the protein CD36.

7 Dec 2016

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Nearly every cell in the human body has one or more protrusive structures called cilia or flagella.

7 Dec 2016

Scientists reveal key insight into how immune system recognises TB

Every 18 seconds someone dies from tuberculosis (TB). It is the world's most deadly infectious disease.

7 Dec 2016

Cedars-Sinai receives $7.3 million grant to test safety of novel cell-based therapy in treating PAH

Researchers from the Cedars-Sinai Heart Institute and the Cedars-Sinai Department of Medicine are expanding their ongoing evaluation of a novel cell-based therapeutic candidate into the area of pulmonary arterial hypertension (PAH).

6 Dec 2016

Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells.

6 Dec 2016

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue.

5 Dec 2016

New drug treatment can override genetic fault that causes choroideremia

Researchers with funding from Fight for Sight have demonstrated that a new drug treatment for cystic fibrosis and Duchenne muscular dystrophy can override a genetic fault that causes choroideremia – a severe blinding disorder.

5 Dec 2016

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Researchers are reporting the highest and most sustained levels to date of the essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B.

4 Dec 2016

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs.

1 Dec 2016

Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

An international group of researchers report success in mice of a method of using positron emission tomography scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in prostate cancer.

1 Dec 2016

New study shows link between metabolic syndrome and cognitive abilities in U.S. adolescents

A new study of U.S. adolescents shows an association between metabolic syndrome and impairments in reading, attention, and working memory.

30 Nov 2016

MILabs to provide Adaptive X-ray CT system to UAB for advancing pulmonary research

MILabs will provide an advanced U-CTUHR microCT system to the Cystic Fibrosis Research Center (CFRC) at the University of Alabama at Birmingham (UAB).

30 Nov 2016

Scientists identify ‘cellular post office’ that could be key to preventing spread of lung cancer

Scientists at the Universities of York and Texas have found that a component of cancer cells, which acts like a 'cellular post office', could be the key to preventing the spread of lung cancer to other parts of the body.

25 Nov 2016

Organic chemists develop method for rapid formation of optically active α-aminocarbonyl therapeutics

A team of organic chemists at ITbM, Nagoya University, has developed a new reaction to directly install amines into carbonyl compounds using their unique phase-transfer catalyst.

24 Nov 2016

Scientists take one step forward by finding how antibody neutralizes Zika infection

As Zika spreads throughout the world, the call for rapid development of therapeutics to treat Zika rings loud and clear.

24 Nov 2016

New postnatal mouse model closely mimics fetal brain abnormalities caused by Zika infection

A team of scientists led by researchers at the University of Georgia has developed a new mouse model that closely mimics fetal brain abnormalities caused by the Zika virus in humans.

22 Nov 2016

Study highlights potential to develop antiviral therapies, vaccines for treating astroviruses

Human astroviruses infect nearly everyone during childhood, causing diarrhea, vomiting, and fever.

22 Nov 2016

Low-calorie diet and exercise could improve kidney function in patients with NASH

Non-alcoholic steatohepatitis (NASH) is a potentially serious liver condition characterized by excess fat in the liver associated with inflammation and scarring.

21 Nov 2016

Study finds way to detect early signs of AD by looking at retina of patients' eyes

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain.

18 Nov 2016

Preserving donor lungs for longer time may provide greater flexibility during transplants

A new method which doubles the usual time donor lungs can remain outside the body can benefit patients, staff and allow retrieval of donor lungs across greater geographical areas, says a study published in The Lancet Respiratory Medicine.

17 Nov 2016

Therapeutics News and Research

Study shows involvement of lipid metabolism in tumour metastasis

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Scientists reveal key insight into how immune system recognises TB

Cedars-Sinai receives $7.3 million grant to test safety of novel cell-based therapy in treating PAH

Experimental T-cell therapy shows promise in preventing AML relapse

Research unlocks potential new therapies for inflammatory diseases

New drug treatment can override genetic fault that causes choroideremia

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

New study shows link between metabolic syndrome and cognitive abilities in U.S. adolescents

MILabs to provide Adaptive X-ray CT system to UAB for advancing pulmonary research

Scientists identify ‘cellular post office’ that could be key to preventing spread of lung cancer

Organic chemists develop method for rapid formation of optically active α-aminocarbonyl therapeutics

Scientists take one step forward by finding how antibody neutralizes Zika infection

New postnatal mouse model closely mimics fetal brain abnormalities caused by Zika infection

Study highlights potential to develop antiviral therapies, vaccines for treating astroviruses

Low-calorie diet and exercise could improve kidney function in patients with NASH

Study finds way to detect early signs of AD by looking at retina of patients' eyes

Preserving donor lungs for longer time may provide greater flexibility during transplants

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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