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Researchers identify underlying molecular mechanism of cardiac hypertrophy

Specific genes are responsible for determining cell growth and differentiation during the early stages of cardiac development. Reactivation of these genes later in life can lead to an abnormal thickening of the heart muscle. Researchers from Charité -- Universitätsmedizin Berlin lead by Professor Silke Rickert-Sperling have been able to identify the underlying molecular mechanism.

23 Dec 2015

FDA approves Uptravi tablets to treat adults with pulmonary arterial hypertension

On December 21, the U.S. Food and Drug Administration approved Uptravi (selexipag) tablets to treat adults with pulmonary arterial hypertension (PAH), a chronic, progressive, and debilitating rare lung disease that can lead to death or the need for transplantation.

22 Dec 2015

Excess body fat may affect bone growth in children

Studies have shown that obese children tend to have more muscle, but recent University of Georgia research on the muscle and bone relationship shows that excess body fat may compromise other functions in their bodies, such as bone growth.

22 Dec 2015

Scientists uncover novel strategy to block cancer's spread, restore tumor vulnerability to chemotherapy

St. Jude Children's Research Hospital scientists have discovered how an aggressive tumor of the muscle and soft tissue hijacks an export pathway in cells to lay the groundwork for cancer progression and resistance to chemotherapy.

22 Dec 2015

Study on myosins may lead to therapies for muscle diseases, cancers

Understanding how tiny molecular motors called myosins use energy to fuel biological tasks like contracting muscles could lead to therapies for muscle diseases and cancers, says a team of researchers led by Penn State College of Medicine scientists.

22 Dec 2015

Aquinnah secures $5 million private equity investment from Takeda

Aquinnah Pharmaceuticals announced today that it has received a $5 Million investment from Takeda Pharmaceutical Company, Limited, in it's first private equity financing. The company has assembled a world-class team of drug developers and an exceptional Scientific Advisory Board in the fields of Amyotrophic Lateral Sclerosis (ALS), protein and RNA regulation, and neurodegenerative diseases.

21 Dec 2015

Endoscopic submucosal dissection appears to be effective treatment for patients with throat cancer

According to a study in the December issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy, endoscopic submucosal dissection (ESD) appears to be a safe and effective minimally invasive treatment for patients with superficial pharyngeal (throat) cancer.

20 Dec 2015

UIC's orthopaedic residency program earns accreditation from American Physical Therapy Association

Physical therapists who want to advance their skills and opportunities can apply to a 13-month orthopaedic residency program at the University of Illinois at Chicago that emphasizes training along with patient care.

18 Dec 2015

Study examines whether treating multiple narrowed arteries has adverse effect on the heart

A new study has examined the effects on the heart of treating multiple narrowed arteries - rather than just one - at the time of a heart attack.

18 Dec 2015

Zoledronate drug can protect stem cells from ageing

Stem cells can be protected from the effects of ageing by a drug currently used to treat patients with osteoporosis, a breakthrough study has found.

17 Dec 2015

New study suggests that musclin may promote muscle health

A new study in mice shows that exercise causes muscle to release a peptide that builds the muscle's capacity for energy production and increases physical endurance, allowing for longer and more intense exercise.

17 Dec 2015

Scientists reveal major players in severe muscle damage caused by sepsis

Scientists from the Institut Pasteur, Paris Descartes University, Sainte-Anne Hospital and the CNRS have recently published a paper in Nature Communications in which they reveal major players in the severe muscle damage caused by sepsis, or septicemia, which explains why many patients suffer debilitating muscle impairment long-term after recovery.

17 Dec 2015

Study highlights strong need for weight management before menopause

At midlife, overweight and obesity, lack of exercise, less education, and low income put women at much higher risk of having metabolic syndrome, the cluster of conditions predisposes people to diabetes and heart disease, shows a large study published today in Menopause, the journal of The North American Menopause Society.

16 Dec 2015

Children from low income environments experience higher risk of neurological impairment

Children from low income environments appear to have a higher risk of neurological impairment than those from more economically secure circumstances, according to researchers at the National Institutes of Health and other institutions. This neurological impairment appears to be distinct from the risk of cognitive and emotional delays known to accompany early-life poverty.

16 Dec 2015

Bridion injection approved to reverse effects of neuromuscular blocking drugs used during certain types of surgery

The U.S. Food and Drug Administration today approved Bridion (sugammadex) injection to reverse the effects of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide, which are used during certain types of surgery in adults.

16 Dec 2015

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

Researchers from the University of Arkansas for Medical Sciences and other institutions are reporting the discovery of the first broad spectrum drug that can potently kill senescent (or aging) cells in culture and effectively clear the cells in animals by specifically targeting a pathway that is critical for the survival of senescent cells.

15 Dec 2015

New study examines antioxidant effects of pomegranate extract on cardiovascular risk factors

A new study assessing the antioxidant effects of pomegranate extract on cardiovascular risk factors and muscle function showed reductions in blood pressure and some atheroprotective benefits, but no effects on inflammation, oxidative strength, or muscle strength.

15 Dec 2015

Viralytics announces completion of $28 million placement

Viralytics Limited announces that it has completed a placement of 46,118,270 shares to international and domestic sophisticated or professional investors at an issue price of $0.615 per share to raise $28,362,736.

14 Dec 2015

Nutritionist offers myriad methods to help people eat during cancer treatment

Ernestine Trujillo, MS, RD, LD, plays an important role in helping people through their cancer treatment: she helps them to eat. Eating keeps their strength up so that they can get through treatment. But eating during cancer treatment isn't always easy. Trujillo, a Senior Clinical Nutritionist at the University of New Mexico Comprehensive Cancer Center, offers myriad methods to help people get the nutrition they need.

13 Dec 2015

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

The U.S. Food and Drug Administration today approved Alecensa (alectinib) to treat people with advanced (metastatic) ALK-positive non-small cell lung cancer (NSCLC) whose disease has worsened after, or who could not tolerate treatment with, another therapy called Xalkori (crizotinib).

11 Dec 2015

Muscle News and Research

Researchers identify underlying molecular mechanism of cardiac hypertrophy

FDA approves Uptravi tablets to treat adults with pulmonary arterial hypertension

Excess body fat may affect bone growth in children

Scientists uncover novel strategy to block cancer's spread, restore tumor vulnerability to chemotherapy

Study on myosins may lead to therapies for muscle diseases, cancers

Aquinnah secures $5 million private equity investment from Takeda

Endoscopic submucosal dissection appears to be effective treatment for patients with throat cancer

UIC's orthopaedic residency program earns accreditation from American Physical Therapy Association

Study examines whether treating multiple narrowed arteries has adverse effect on the heart

Zoledronate drug can protect stem cells from ageing

New study suggests that musclin may promote muscle health

Scientists reveal major players in severe muscle damage caused by sepsis

Study highlights strong need for weight management before menopause

Children from low income environments experience higher risk of neurological impairment

Bridion injection approved to reverse effects of neuromuscular blocking drugs used during certain types of surgery

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

New study examines antioxidant effects of pomegranate extract on cardiovascular risk factors

Viralytics announces completion of $28 million placement

Nutritionist offers myriad methods to help people eat during cancer treatment

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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