Anemia News and Research

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Anemia is a decrease in normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis). Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few.

New treatment for adults with rare, life-threatening blood disease receives FDA approval

The U.S. Food and Drug Administration today approved Ultomiris (ravulizumab) injection for the treatment of adult patients with paroxysmal nocturnal hemoglobinuria (PNH), a rare and life-threatening blood disease.

21 Dec 2018

Baculovirus virion completely eliminates liver-stage parasites in mouse model

Currently, few antimalarial treatments exist that effectively kill liver-stage malaria parasites, which can lay dormant for months or years as in the case of Plasmodium vivax. Researchers from Kanazawa University have successfully demonstrated that administration of a baculovirus virion completely eliminates liver-stage parasites in a mouse model via BV-induced fast-acting innate immunity.

13 Dec 2018

Novel way to efficiently deliver anti-parasitic medicines

Scientists have developed a new way to deliver anti-parasitic medicines more efficiently.

12 Dec 2018

Protecting powerhouse of cells could provide better way to treat acute kidney injury

For the first time, scientists have described the body's natural mechanism for temporarily protecting the powerhouses of kidney cells when injury or disease means they aren't getting enough blood or oxygen.

6 Dec 2018

App that could detect level of anemia by looking at fingernails

Researchers from the Emory University have developed a new phone app that needs just a colour photograph of the nail beds of an individual to detect anemia in them. The results of the report titled, “Smartphone app for non-invasive detection of anemia using only patient-sourced photos,” were published in the latest issue of the journal Nature Communications.

5 Dec 2018

Advances in gene therapy for inherited blood disorders

Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.

4 Dec 2018

Russian researchers develop novel combined action drug for cancer diagnostics and treatment

Russian researchers announced the development of a combined action drug based on ionizing radiation and bacterial toxin. Their total effect appeared to be 2,200 times stronger compared to that exerted by the radiation and toxin, separately.

4 Dec 2018

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common.

3 Dec 2018

Study examines whether taking multiple medications for heart failure can limit abilities in older adults

As we age, we tend to develop a number of chronic health conditions and concerns. Often, managing health problems can mean that older adults may take many different medications. When older adults take five or more medicines (a scenario health experts call "polypharmacy", it can increase the risk of harmful side effects.

3 Dec 2018

Daily hydroxyurea treatment may bring some relief for African children with sickle cell anemia

A daily hydroxyurea pill may finally bring some relief for young children living with the painful and deadly blood disease sickle cell anemia in resource-challenged sub-Saharan Africa, where the disease is prevalent and health care availability is suboptimal.

3 Dec 2018

Johns Hopkins researchers report challenges in treating severe crisis pain of sickle cell disease

In a study tracking the severe crisis pain of sickle cell disease and its management in 73 adults over a period of a year, Johns Hopkins researchers found that even among those on high doses of daily at-home opioids, a persistent subset was more likely to seek emergency hospital care for crisis pain and was less likely to have the pain controlled by intensive treatment.

27 Nov 2018

FDA approves new treatment for AML patients

The U.S. Food and Drug Administration today approved Daurismo (glasdegib) tablets to be used in combination with low-dose cytarabine (LDAC), a type of chemotherapy, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adults who are 75 years of age or older or who have other chronic health conditions or diseases (comorbidities) that may preclude the use of intensive chemotherapy.

22 Nov 2018

New first-line treatment for peripheral T-cell lymphoma approved by FDA

The U.S. Food and Drug Administration today expanded the approved use of Adcetris (brentuximab vedotin) injection in combination with chemotherapy for adult patients with certain types of peripheral T-cell lymphoma.

16 Nov 2018

New oral drug reduces menstrual bleeding for women with common uterine tumors

A new oral drug significantly reduced menstrual bleeding for women with the most common gynecologic tumors in the United States - benign tumors that disproportionately affect African-Americans, an international clinical trial found.

9 Nov 2018

Study identifies novel missense mutation affecting YARS causes multisystem disease

Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals.

7 Nov 2018

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell lung cancer whose disease has progressed on crizotinib and at least one other ALK inhibitor for metastatic disease; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease.

5 Nov 2018

Anemia News and Research

Further Reading

New treatment for adults with rare, life-threatening blood disease receives FDA approval

Baculovirus virion completely eliminates liver-stage parasites in mouse model

Novel way to efficiently deliver anti-parasitic medicines

Protecting powerhouse of cells could provide better way to treat acute kidney injury

App that could detect level of anemia by looking at fingernails

Advances in gene therapy for inherited blood disorders

Russian researchers develop novel combined action drug for cancer diagnostics and treatment

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

Study examines whether taking multiple medications for heart failure can limit abilities in older adults

Daily hydroxyurea treatment may bring some relief for African children with sickle cell anemia

Johns Hopkins researchers report challenges in treating severe crisis pain of sickle cell disease

FDA approves new treatment for AML patients

New first-line treatment for peripheral T-cell lymphoma approved by FDA

New oral drug reduces menstrual bleeding for women with common uterine tumors

Study identifies novel missense mutation affecting YARS causes multisystem disease

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Researchers discover biomarker for most common type of heart failure

Research highlights lack of data on European children's nutrient intake levels

High-impact clinical trial results could affect kidney-related medical care

Better blood pressure control may prevent organ damage related to hypertensive emergencies in diabetics

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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