Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Samumed to present preclinical and clinical data on Wnt pathway for OA treatment at ACR 2015

Samumed, LLC, a leader in tissue regeneration, announced today that it will present preclinical and clinical data on a small molecule modulator of the Wnt pathway (SM04690, an investigational new drug) for potential disease modifying treatment of osteoarthritis (OA) of the knee at 2015 American College of Rheumatology Annual Meeting.

4 Nov 2015

Lithium chloride could offer effective treatment against osteoarthritis

Bioengineers from Queen Mary University of London have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment against osteoarthritis by disrupting the length of the cells' antennae called primary cilia.

28 Oct 2015

NHS to produce unique stem cells that could revolutionize treatment for diabetic kidney disease

NHS Blood and Transplant will start producing stem cells for groundbreaking treatment aimed at combating one of the most serious health problems facing the NHS, diabetic kidney disease.

22 Oct 2015

Mordor Intelligence announces publication of ‘Global Sports Medicine Market’ report

Mordor Intelligence is pleased to announce the publication of the report on Global Sports Medicine Market on October 20, 2015. This report discusses the market in detail.

20 Oct 2015

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Ember Therapeutics, Inc., a privately held, New York-based biopharmaceutical company that is developing targeted therapies for osteoarthritis, kidney fibrosis, and other indications using Bone Morphogenetic Protein (BMP)-7, announced today initial results from the Phase II(a) trial of local BMP-7 administration in patients with moderate osteoarthritis of the knee.

20 Oct 2015

Graft properties affect knee ligament surgery outcome more than surgical technique

In anterior cruciate ligament (ACL) reconstruction, graft stiffness and pre-strain play a more vital role than the choice of surgical technique, indicates a new study from the University of Eastern Finland. The study developed a computational 3D model of the knee joint, which can be used in the prevention of osteoarthritis (OA), specifically OA resulting from trauma.

15 Oct 2015

Roche to acquire biotechnology company, Adheron Therapeutics

Adheron Therapeutics, a privately held biotechnology company based in Berkeley, California, United States, announced today that it has agreed to be acquired by Roche.

9 Oct 2015

Surgeons use 3D printing techniques to create low-cost pediatric rib cartilage model

When surgical residents need to practice a complicated procedure to fashion a new ear for children without one, they typically get a bar of soap, carrot or an apple.

1 Oct 2015

Study demonstrates potential of FCPCs as new source for cartilage regeneration

The self-repair of injured cartilage is difficult for several reasons, foremost of which is the lack of blood supply to the tissue. Therapeutic efforts aimed at cartilage repair are often not optimal. Surgical repair techniques often lead to the formation of fibrocartilage, which is weaker and less durable. Although cell transplantation aimed at cartilage repair has been carried out using mesenchymal stem cells (MSCs), varying outcomes have resulted, despite the propensity of MSCs to proliferate and differentiate.

23 Sep 2015

CTCA at Western begins clinical trial that combines immunotherapy with chemotherapy to target sarcomas

Cancer Treatment Centers of America at Western Regional Medical Center in Goodyear, Arizona, has begun Phase II of another arm of its multi-arm clinical trial that combines immunotherapy with chemotherapy.

21 Sep 2015

Orthocell presents successful ‘cell factory’ data at European Bone and Joint Infection Society

Regenerative medicine company Orthocell Limited is pleased to announce the presentation of its successful ‘cell factory’ data at the European Bone and Joint Infection Society in Estoril Portugal September 2015.

16 Sep 2015

New strategy improves bone repair by boosting survival rate of transplanted stem cells

Stem cell therapies are often limited by low survival of transplanted stem cells and the lack of precise control over their differentiation into the terminal cell types needed to repair or replace injured tissues. Now, a team led by Wyss Institute Core Faculty member David Mooney, Ph.D., has developed a new strategy - embedding stem cells into porous, transplantable hydrogels - that has experimentally improved bone repair by boosting the survival rate of transplanted stem cells and influencing their cell differentiation.

15 Sep 2015

Researchers find genetic cause of previously unknown disease

Researchers at the University of Oslo and Oslo University Hospital have found the genetic cause of a previously undescribed disease. With this, they have solved an over ten year old medical conundrum.

1 Sep 2015

Study: Knee or hip replacement surgery may increase heart attack risk

Contrary to recent reports, Boston-based researchers found that osteoarthritis patients who had total knee or hip joint replacement surgery, known as arthroplasty, were at increased risk of heart attack (myocardial infarction) in the early post-operative period.

31 Aug 2015

Scientists develop technique to rejuvenate cells from older osteoarthritis patients

A research team at York has adapted the astonishing capacity of animals such as newts to regenerate lost tissues and organs caused when they have a limb severed.

20 Aug 2015

Transplanting mesenchymal stromal cells derived from amniotic membranes can benefit eye diseases

A team of researchers in South Korea has successfully transplanted mesenchymal stromal cells (MSCs) derived from human amniotic membranes of the placenta (AMSCs) into laboratory mice modeled with oxygen-induced retinopathy (a murine model used to mimic eye disease).

20 Aug 2015

Cartilage News and Research

Further Reading

Samumed to present preclinical and clinical data on Wnt pathway for OA treatment at ACR 2015

Lithium chloride could offer effective treatment against osteoarthritis

NHS to produce unique stem cells that could revolutionize treatment for diabetic kidney disease

Mordor Intelligence announces publication of ‘Global Sports Medicine Market’ report

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Graft properties affect knee ligament surgery outcome more than surgical technique

Roche to acquire biotechnology company, Adheron Therapeutics

Surgeons use 3D printing techniques to create low-cost pediatric rib cartilage model

Study demonstrates potential of FCPCs as new source for cartilage regeneration

CTCA at Western begins clinical trial that combines immunotherapy with chemotherapy to target sarcomas

Orthocell presents successful ‘cell factory’ data at European Bone and Joint Infection Society

New strategy improves bone repair by boosting survival rate of transplanted stem cells

Researchers find genetic cause of previously unknown disease

Study: Knee or hip replacement surgery may increase heart attack risk

Scientists develop technique to rejuvenate cells from older osteoarthritis patients

Transplanting mesenchymal stromal cells derived from amniotic membranes can benefit eye diseases

New study explains why statins are more beneficial than others in some cases

Orthocell presents positive data for Ortho-ATI and Ortho-ACI in patients with damaged cartilage, tendon injuries

Imperial Innovations announces launch of pre-clinical spinout company, Orthonika

AESKU.DIAGNOSTICS offers new early prognostic marker for RA

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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