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Flow Eighteen38 receives €5 million EUR (c.$5.58 million USD) to expand production and biophysical capabilities

Flow Eighteen38, a protein sciences division created to facilitate and accelerate antibody characterization and protein purification projects, today announced a €5 million EUR (c.$5.58 million USD) investment into its protein production and biophysical characterization capabilities and services from its parent company, FairJourney Biologics S.A. (FJB), leaders in the discovery and optimization of antibodies.

From FairJourney Biologics S.A. 8 Mar 2022

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

In a recent study posted to the medRxiv*preprint server, a team of researchers from Israel developed and validated novel reverse transcriptase - quantitative polymerase chain reaction (RT-qPCR) assays. The new assays enable the rapid and high throughput identification and differentiation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 variants.

8 Mar 2022

Identification of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding

Researchers discovered compounds able to inhibit SARS-CoV-2 macrodomain 1 and adenosine diphosphate-ribose binding via high throughput screening.

7 Mar 2022

Canopy Biosciences launches next-generation ChipCytometry™ instrument for spatial biology with sub-cellular resolution

Canopy Biosciences, a Bruker Company, today announced the commercial launch of the CellScape™ system, the next generation in ChipCytometry™ instrumentation, advancing the cutting-edge for quantitative in situ spatial phenotyping.

From Bruker Nano Surfaces and Metrology 7 Mar 2022

Researchers discover functional links between potassium channel gene variants and neonatal epilepsy

Northwestern Medicine scientists have discovered functional links between dozens of potassium channel gene variants and neonatal epilepsy, according to a study published in JCI Insight.

4 Mar 2022

COVID-19 and the life sciences; what have we learned and where are we going?

News-Medical attended the 2022 SLAS press briefing where Peter Simpson, Michael Girardi, and Simon Meffan-Main gave their thoughts on the life sciences sector post-COVID-19.

From Society for Laboratory Automation and Screening (SLAS) 4 Mar 2022

Lipidomic profiling may provide early prediction of type 2 diabetes and cardiovascular disease risk

Simultaneous measurement of dozens of types of fats in the blood ("lipidomics") can predict the risk of developing type 2 diabetes (T2D) and cardiovascular disease (CVD) years in the future, according to a new study publishing March 3rd in the open-access journal PLOS Biology from Chris Lauber of Lipotype, Germany, and colleagues.

3 Mar 2022

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

In a new study, researchers presented the Multiscale potential of heat-diffusion for affinity-based trajectory embedding approach that identified multimodal signatures of SARS-CoV-2shut.

3 Mar 2022

The prevalence of SARS-CoV-2 in environment and animal samples from the Huanan seafood market

A new study describes the surveillance of SARS-CoV-2 within the Huanan seafood market.

2 Mar 2022

AI and machine learning could improve cancer diagnosis through biomarker discovery

Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have transformed many industries and areas of science.

1 Mar 2022

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Researchers used deep mutational scans to measure the effect of each amino-acid mutation in the receptor-binding domain of SARS-CoV-2 Wuhan-Hu-1, Alpha, Beta, Delta, and Eta variants.

1 Mar 2022

Distributed lag models to estimate incident rates using concentrations of SARS-CoV-2 RNA from wastewater solids

The team analyzed the effect of sampling frequency on the prediction error of IRs by using reduced sampling across different sewer sheds of varying sizes and features.

28 Feb 2022

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

In a recent research report from the United States, currently available on bioRxiv* preprint server, scientists have shown that bacterial taxonomic and functional profiles can discriminate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) status even without directly detecting viral transcripts – opening the door for entirely novel approaches in wastewater-based epidemiology.

27 Feb 2022

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Researchers conducted a comprehensive and systematic analysis of functional SARS-CoV-2 antibody profiles in a controlled randomized trial of severe COVID-19 hospitalized individuals treated with COVID-19 CCP.

25 Feb 2022

TGen and Deepcell collaborate to employ AI-based technology to classify and isolate diseased cells

The Translational Genomics Research Institute, an affiliate of City of Hope, is partnering with a Silicon Valley firm to become one of the first research institutes in the world to employ a new Artificial Intelligence-powered imaging and sorting technology to classify and isolate individual diseased cells.

22 Feb 2022

High Throughput News and Research

Flow Eighteen38 receives €5 million EUR (c.$5.58 million USD) to expand production and biophysical capabilities

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

Identification of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding

Canopy Biosciences launches next-generation ChipCytometry™ instrument for spatial biology with sub-cellular resolution

Researchers discover functional links between potassium channel gene variants and neonatal epilepsy

COVID-19 and the life sciences; what have we learned and where are we going?

Lipidomic profiling may provide early prediction of type 2 diabetes and cardiovascular disease risk

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

The prevalence of SARS-CoV-2 in environment and animal samples from the Huanan seafood market

AI and machine learning could improve cancer diagnosis through biomarker discovery

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Distributed lag models to estimate incident rates using concentrations of SARS-CoV-2 RNA from wastewater solids

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

TGen and Deepcell collaborate to employ AI-based technology to classify and isolate diseased cells

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

Allegra V-15R benchtop centrifuge launched by Beckman Coulter Life Sciences during diamond year celebration

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

Group cell movement could be harnessed to stop cancer spread, study suggests

Researchers identify a powerful combination of antivirals to treat COVID-19

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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