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C. diff uses toxic compound to gain competitive advantage in the gut

The pathogen C. diff - the most common cause of health care-associated infectious diarrhea - can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut.

25 Mar 2025

Blocking an inflammatory receptor in the retinas of aging mice improves retinal health

A new research paper was published in Aging (Aging-US) on January 31, 2025, in Volume 17, Issue 2, titled "Cysteinyl leukotriene receptor 1 modulates retinal immune cells, vascularity and proteolytic activity in aged mice."

25 Mar 2025

New trial aims to make rectal cancer more responsive to radiation

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, has opened a phase 1 trial seeking to one day transform rectal cancer from a mostly radiation-resistant disease to one that can be cured using radiation and chemotherapy.

25 Mar 2025

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Four breakthrough studies could revolutionize tuberculosis treatment

As of early 2025, tuberculosis cases are increasing in the U.S. This disease, often shortened to TB, causes significant lung damage and, if not treated, is almost always lethal.

22 Mar 2025

Scientists decode differentiation pathways of human blood stem cells

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

21 Mar 2025

Melanoma cells use stealth strategy to survive targeted therapy

Researchers have uncovered a stealth survival strategy that melanoma cells use to evade targeted therapy, offering a promising new approach to improving treatment outcomes.

20 Mar 2025

Targeted rehab exercises improve lung health and mobility in long COVID patients

Pulmonary rehabilitation significantly improves physical capacity, lung function, and quality of life in long COVID patients, with the greatest benefits seen in 4-8 week programs combining breathing and multicomponent exercises.

20 Mar 2025

New cannabis formula will help epilepsy, multiple sclerosis sufferers

Scientists at the University of South Australia have come up with an innovative solution to improve the effectiveness of cannabidiol to treat epilepsy, multiple sclerosis and other neurodegenerative diseases.

20 Mar 2025

Breakthrough in cannabidiol formulation improves treatment for epilepsy and MS

19 Mar 2025

Cyanotic congenital heart disease incidence increases in states with restrictive abortion laws

The incidence of babies born with serious heart defects, known as cyanotic congenital heart disease (CCHD), rose in states that enacted restrictive abortion laws following the U.S. Supreme Court's 2022 ruling that put abortion laws in the hands of the states, according to a study being presented at the American College of Cardiology's Annual Scientific Session.

18 Mar 2025

Cannabis use found to raise heart attack risk among younger adults

Marijuana is now legal in many places, but is it safe? Two new studies add to mounting evidence that people who use cannabis are more likely to suffer a heart attack than people who do not use the drug, even among younger and otherwise healthy adults.

18 Mar 2025

Tunneling Nanotube-Like Structures found to play a critical role in heart formation

From his lab at the University of Houston College of Pharmacy Drug Discovery Institute, Mingfu Wu, associate professor, is offering new hope for treating heart disease by sharing his insights into the fundamental process of how the heart is formed in utero.

17 Mar 2025

Advances in organ preservation techniques and future prospects

A review article published in Engineering delves into the crucial field of organ preservation, exploring its history, current techniques, and future prospects.

14 Mar 2025

How gut health shapes heart disease risk — and what you can do about it

A new review highlights how gut microbiome imbalances contribute to cardiovascular disease by altering short-chain fatty acids, TMAO, and inflammatory pathways. The study emphasizes the potential of prebiotics, probiotics, and dietary changes to restore gut health and reduce heart disease risk.

13 Mar 2025

How eating more calories helps lower asthma risk in children - but only up to a point

Children and adolescents in the U.S. who consume higher amounts of dietary energy have a lower risk of asthma, but this protective effect stops beyond 56.442 kcal per kilogram of body weight per day. The study found an L-shaped relationship, suggesting that insufficient energy intake may heighten asthma risk.

12 Mar 2025

Integrated anti-aging strategy could reduce neurodegeneration

Aging significantly impacts neurodegeneration, increasing risks for diseases like Alzheimer's. Research focuses on therapies to enhance cognitive function.

11 Mar 2025

Decoding programmed cell death in breast cancer

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC remains a significant global health challenge.

11 Mar 2025

Cordycepin helps tired mice run longer and think better, study finds

Researchers show that cordycepin, a compound from Cordyceps militaris, can boost endurance and protect brain function in mice exhausted by excessive exercise.

10 Mar 2025

Study reveals genes critical for tuberculosis survival during transmission

Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person's lungs to another person's during coughing, sneezing or talking, according to researchers from Weill Cornell Medicine and the Massachusetts Institute of Technology.

10 Mar 2025