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Newly discovered genetic disorder opens way for future diabetes drugs

Knowledge of a newly discovered genetic disorder, which means that a person cannot produce the protein TXNIP (thioredoxin interacting protein) in their cells, can open for the development of new diabetes drugs.

12 Feb 2019

NIH scientists zero in on genes associated with AMD

National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration, a leading cause of vision loss and blindness among people age 65 and older.

12 Feb 2019

Rapid progression of age-related diseases may result from formation of vicious cycles

Biologist Aleksey Belikov from the Moscow Institute of Physics and Technology has proposed that rapid progression of age-related diseases may result from the formation of so-called vicious cycles. An example of this is when toxic products of a biochemical reaction trigger that same reaction to happen again.

12 Feb 2019

Researchers map extremely complex chromosome aberrations using DNA puzzle pieces

Using puzzle pieces from four different DNA analyses, researchers at Karolinska Institutet in Sweden have been able to map three extremely complex chromosome aberrations.

12 Feb 2019

Scientists develop machine-learning approach to identify source of Salmonella

A team of scientists led by researchers at the University of Georgia Center for Food Safety in Griffin has developed a machine-learning approach that could lead to quicker identification of the animal source of certain Salmonella outbreaks.

12 Feb 2019

Research sheds light on how motor enzyme can promote genome integrity

Approximately one per cent of each organism's genome encodes helicases. Helicases are mostly known as motor enzymes that can unwrap double-stranded DNA by use of energy.

11 Feb 2019

Scientists uncover main mechanisms of fluconazole drug resistance

The yeast Candida albicans occurs in most healthy people as a harmless colonizer in the digestive tract. However, it can also cause life-threatening infections, especially in immunocompromised patients.

11 Feb 2019

Researchers identify genes that make Staphyloccocus bacteria resistant to treatment

A Rutgers-led team has discovered two genes that make some strains of harmful Staphyloccocus bacteria resistant to treatment by copper, a potent and frequently used antibacterial agent.

11 Feb 2019

Scientists develop novel way with genome sequences to study widespread form of malaria

Scientists at the Institute of Genome Sciences at the University of Maryland School of Medicine have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately eradicate Plasmodium vivax, the most widespread form of malaria. P. vivax is a single-celled transmitted by mosquitoes.

11 Feb 2019

Metabolic plasticity helps metastatic cancer cells survive hostile environments

When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments.

8 Feb 2019

IAS 2019 plenary program spotlights urgent developments in HIV science

The International AIDS Society has announced the plenary presentations that will lead the 10th IAS Conference on HIV Science, which will take place in Mexico City, Mexico, on 21-24 July 2019. IAS 2019 is the largest open scientific conference on HIV and is expected to bring together more than 6,000 participants from more than 140 countries.

8 Feb 2019

IDT supports innovative synthetic biology start-ups with grant program

Integrated DNA Technologies’ Synthetic Biology Start-up Grant Program has once again benefited innovative start-ups in their missions to impact sustainable manufacturing, human health, and/or humanitarian causes.

From Integrated DNA Technologies 8 Feb 2019

Scientists receive $1.5 million to develop new technology for detecting healthcare-associated infections

Healthcare-associated infections are the fourth leading cause of death in Canada, predicted to move up to second place by 2050.

8 Feb 2019

Cloning-free Nested CRISPR uses long DNA fragments for efficient gene editing

CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. However, even though it allows the creation or correction of mutations consisting of a single or few nucleotides with relative ease, it still possesses limitations upon introducing larger fragments of DNA in the genome.

8 Feb 2019

Vilcek Foundation prizes awarded to immigrants for their work on human biology and disease

The Vilcek Foundation is pleased to announce the winners of the 2019 Vilcek Foundation Prizes for Biomedical Science, awarded to immigrants who have made significant contributions to the field. Dr. Angelika Amon will receive the $100,000 Vilcek Prize, while Drs. Amit Choudhary, Jeanne T. Paz, and Mikhail G. Shapiro will each receive the $50,000 Vilcek Prize for Creative Promise.

8 Feb 2019

Researchers reveal novel computational tool used to analyze genetic variation

The field of genetic sequencing has undergone a dramatic revolution over the past 20 years. In 2001 the first copy of the three billion base pairs that assemble the human genome was published.

8 Feb 2019

Mutations in folliculin gene affect embryo implantation

New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the wall of the uterus, the cells must exit their pre-implantation state and be ready for post-implantation development.

7 Feb 2019

Insufficient sleep mirrored by DNA from blood leukocytes

An insufficient amount of sleep and qualitatively poor sleep are common among the general population. Prior studies have indicated that prolonged insufficient sleep and poor sleep quality are associated with a heightened risk of cardiovascular diseases, dementia and psychiatric disorders, particularly depression, yet the molecular mechanisms underlying this connection are not well known.

7 Feb 2019

ALS and Tow Foundation announce their continuing support to New York Genome Center

The ALS Association and The Tow Foundation are pleased to announce their continuing support of the New York Genome Center's Center for Genomics of Neurodegenerative Disease, in recognition of the substantial genomic research being carried out by NYGC scientists.

6 Feb 2019

Large genetic analysis of impulsiveness reveals links with psychiatric disorders

Impulsiveness and substance use share a genetic basis, according to genome-wide association studies published in JNeurosci by academic and industry researchers.

From Society for Neuroscience 5 Feb 2019

Genome News and Research

Newly discovered genetic disorder opens way for future diabetes drugs

NIH scientists zero in on genes associated with AMD

Rapid progression of age-related diseases may result from formation of vicious cycles

Researchers map extremely complex chromosome aberrations using DNA puzzle pieces

Scientists develop machine-learning approach to identify source of Salmonella

Research sheds light on how motor enzyme can promote genome integrity

Scientists uncover main mechanisms of fluconazole drug resistance

Researchers identify genes that make Staphyloccocus bacteria resistant to treatment

Scientists develop novel way with genome sequences to study widespread form of malaria

Metabolic plasticity helps metastatic cancer cells survive hostile environments

IAS 2019 plenary program spotlights urgent developments in HIV science

IDT supports innovative synthetic biology start-ups with grant program

Scientists receive $1.5 million to develop new technology for detecting healthcare-associated infections

Cloning-free Nested CRISPR uses long DNA fragments for efficient gene editing

Vilcek Foundation prizes awarded to immigrants for their work on human biology and disease

Researchers reveal novel computational tool used to analyze genetic variation

Mutations in folliculin gene affect embryo implantation

Insufficient sleep mirrored by DNA from blood leukocytes

ALS and Tow Foundation announce their continuing support to New York Genome Center

Large genetic analysis of impulsiveness reveals links with psychiatric disorders

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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