Efficacy News and Research

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Previously infected vaccinees broadly neutralize SARS-CoV-2 variants of concern

Researchers in the United States have conducted a study demonstrating the effectiveness of first-generation vaccines at protecting against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals who have previously been infected with the virus.

2 May 2021

Arresting tumor growth for a variety of cancers through T cell engineering

Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it's possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues.

30 Apr 2021

FDA approves new drug for treatment of adults with chronic kidney disease

Today, the U.S. Food and Drug Administration approved Farxiga (dapagliflozin) oral tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular death and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression.

30 Apr 2021

Friendly gut bacteria emerged as an invaluable ally in the battle against malnutrition

Treating malnutrition by boosting gut microbes produces better results than traditional nutritional supplements.

30 Apr 2021

Vaccines can save lives and safeguard health and well-being

Effectively and safely protecting against disease--this is what makes vaccines a vital and successful public health tool that saves lives and safeguards health and well-being. Today, vaccines shield us from more than 20 life-threatening diseases.

30 Apr 2021

FDA approves higher dose naloxone hydrochloride nasal spray product to combat opioid overdose

The U.S. Food and Drug Administration announced today the approval of a higher dose naloxone hydrochloride nasal spray product to treat opioid overdose. The newly approved product delivers 8 milligrams (mg) of naloxone into the nasal cavity. The FDA had previously approved 2 mg and 4 mg naloxone nasal spray products.

30 Apr 2021

Hepatitis C antivirals synergize with remdesivir to inhibit SARS-CoV-2 in vitro

A new study sheds light on the potential of drug combinations to stem viral transmission and treat patients with COVID-19. It also shows that four drugs used to treat hepatitis C synergize with remdesivir to make it up to ten times more effective at inhibiting SARS-CoV-2 in cell cultures.

30 Apr 2021

Study develops COVID-19 pandemic reopening strategies in California

A working paper from researchers at the RAND corporation explores the various options to come up with a proposed robust plan for reopening up regions where vaccines have not yet been deployed across the entire population.

30 Apr 2021

Study shows how tau spreads to four distinct patterns leading to different Alzheimer's symptoms

Alzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns that lead to different symptoms with different prognoses of the affected individuals.

30 Apr 2021

Reforms can be sustained only when criminal justice staff view them as legitimate, reveals study

Researchers commonly work with the criminal justice system to implement reforms, bringing with them the latest science and data pointing to why a certain practice will help improve outcomes. New research from the University of Kansas shows if community corrections agencies are to sustain evidence-based reforms, they need to view them as legitimate.

30 Apr 2021

Study: Republicans became increasingly vaccine hesitant over the course of the pandemic

Individuals who self-identify as Republicans became more skeptical of a potential COVID-19 vaccine and other inoculations, such as the flu shot, over the course of the pandemic, reveals a new study by the University of California San Diego's Rady School of Management.

30 Apr 2021

Monoclonal antibody CT-P59 shows preclinical efficacy against South African SARS-CoV-2 variant

Researchers in the Republic of Korea (South Korea), The Netherlands, and South Africa have demonstrated the potential of the monoclonal antibody CT-P59 as an effective therapeutic for coronavirus disease 2019 (COVID-19) caused by the South African B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

29 Apr 2021

High-powered MRI detects subtle differences in the hippocampus of people with Down syndrome

Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus--a region of the brain tied to memory and learning.

29 Apr 2021

Researchers characterize a large set of therapeutic antibodies against SARS-CoV-2 variants

A team of scientists from A-Alpha Bio., USA, has recently conducted a large-scale screening of 33 therapeutic antibodies to examine their binding affinity to a number of SARS-CoV-2 variants. The team analyzed the impact of potential mutations in the spike RBD on antibody efficacy.

29 Apr 2021

COVID-19 vaccination willingness in Australia hinges on public perception of health threat

A new study reports the results of a survey in Australia on vaccine willingness at two points: the first wave in April 2020, and during November of the same year, when cases had dropped significantly.

29 Apr 2021

New insights into how South African SARS-CoV-2 variant sacrifices tight binding for antibody evasion

The highly infectious SARS-CoV-2 variant that recently emerged in South Africa, known as B.1.351, has scientists wondering how existing COVID-19 vaccines and therapies can be improved to ensure strong protection.

29 Apr 2021

Researchers receive $3.75 million to study the impact of fluid flow on CAR-T cell therapy for brain cancer

Glioblastoma multiforme is among the most lethal of cancers and the most stubborn in the face of treatment. Fewer than 20 percent of patients survive more than two years after diagnosis, according to the Central Brain Tumor Registry of the United States.

29 Apr 2021

Potent monoclonal antibody shows promise against emerging SARS-CoV-2 variants of concern

In a new study currently available on the bioRxiv* preprint server, a group of US-based researchers developed a panel of neutralizing monoclonal antibodies against SARS-CoV-2 that can block viral attachment to cells – and pinpointed a specific one that can potently neutralize all tested variants of concern.

28 Apr 2021

Safety and efficacy of Pfizer and AstraZeneca COVID-19 vaccines even better than clinical trials predicted

Researchers in the UK and United States have demonstrated the efficacy of one dose of either the Pfizer-BioNTech or Oxford-AstraZeneca vaccine against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a real-world community setting in the UK.

28 Apr 2021

Virtual reality could be a valuable tool for preventing falls in older people

Researchers at the University of Bath investigating how virtual reality (VR) can help improve balance believe this technology could be a valuable tool in the prevention of falls.

28 Apr 2021

Efficacy News and Research

Previously infected vaccinees broadly neutralize SARS-CoV-2 variants of concern

Arresting tumor growth for a variety of cancers through T cell engineering

FDA approves new drug for treatment of adults with chronic kidney disease

Friendly gut bacteria emerged as an invaluable ally in the battle against malnutrition

Vaccines can save lives and safeguard health and well-being

FDA approves higher dose naloxone hydrochloride nasal spray product to combat opioid overdose

Hepatitis C antivirals synergize with remdesivir to inhibit SARS-CoV-2 in vitro

Study develops COVID-19 pandemic reopening strategies in California

Study shows how tau spreads to four distinct patterns leading to different Alzheimer's symptoms

Reforms can be sustained only when criminal justice staff view them as legitimate, reveals study

Study: Republicans became increasingly vaccine hesitant over the course of the pandemic

Monoclonal antibody CT-P59 shows preclinical efficacy against South African SARS-CoV-2 variant

High-powered MRI detects subtle differences in the hippocampus of people with Down syndrome

Researchers characterize a large set of therapeutic antibodies against SARS-CoV-2 variants

COVID-19 vaccination willingness in Australia hinges on public perception of health threat

New insights into how South African SARS-CoV-2 variant sacrifices tight binding for antibody evasion

Researchers receive $3.75 million to study the impact of fluid flow on CAR-T cell therapy for brain cancer

Potent monoclonal antibody shows promise against emerging SARS-CoV-2 variants of concern

Safety and efficacy of Pfizer and AstraZeneca COVID-19 vaccines even better than clinical trials predicted

Virtual reality could be a valuable tool for preventing falls in older people

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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