Efficacy News and Research

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Artificial super stool may be a game-changer in the treatment of chronic gut infections

The urgent need for human stool donations to treat chronic gut infections could soon be eased with innovative research to develop artificial super stool.

28 Apr 2021

Study examines mRNA COVID-19 vaccine’s effectiveness across age and gender

The findings reveal that although the two-dose vaccine regimen initially induces robust antibody response in all age groups, older male individuals are particularly associated with a gradual decline in vaccine-induced immunity six weeks after the second vaccine dose.

28 Apr 2021

Can control theory explain differences in virulence and transmission of SARS-CoV-2?

A new study discusses variations in viral pathogenicity and in transmission, which are responsible for asymptomatic infection and for superspreading events. The ability to understand this would open the way to understand how this virus behaves the way it does, in terms of its virulence, its spread, and its emergent variants of concern.

28 Apr 2021

Peptide nucleocapsid vaccine candidate elicits protective T cell immunity against SARS-CoV-2 in vivo

A new study describes a synthetic peptide used as a platform to generate protective adaptive cellular immunity to the virus in rhesus macaques, which are the gold standard for preclinical testing in humans.

28 Apr 2021

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

Scientific studies rarely focus on long non-coding RNA molecules (lncRNAs), even though they potentially regulate several diseases. The role of several lncRNAs in anti-viral inflammatory response regulation has recently been reported.

28 Apr 2021

Clinical trial to test existing antibiotic for treating serious S. aureus infections begins

A clinical trial to test the antibiotic dalbavancin for safety and efficacy in treating complicated Staphylococcus aureus (S. aureus) bacteremia has begun.

27 Apr 2021

Pfizer-BioNTech (BNT162b2) vaccine successfully curbs COVID-19 in Israel

Researchers in Israel have shown that three national programs established by the Israeli government have successfully reduced cases of severe coronavirus disease 2019 (COVID-19) and death caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Apr 2021

ANTICOV clinical trial to test new treatment for people with mild-to-moderate COVID-19 in Africa

The ANTICOV clinical trial, conducted in 13 African countries, has started the recruitment of participants to test a new drug combination, nitazoxanide + ciclesonide, to treat people with mild-to-moderate COVID-19 before their cases become severe.

27 Apr 2021

What is the role of nanotechnology in the current COVID-19 outbreak?

The nanotechnology-based medicine platforms against COVID-19 bears hope for relief from the pandemic to save lives and mitigate the infection as part of a broader global public health agenda.

27 Apr 2021

Nucleocapsid-based vaccines may prevent SARS-CoV-2 dissemination to distal organs

A team of scientists recently investigated and compared the efficacy of spike-based and nucleocapsid-based COVID-19 vaccines in mice infected with SARS-CoV-2. Their findings reveal that nucleocapsid-based vaccines are effective in preventing SARS-CoV-2 infection in distal organs, such as the brain.

27 Apr 2021

Study highlights the psychological and social concerns of musculoskeletal trauma patients

Musculoskeletal injuries comprise a large percentage of hospital admissions for adults and often lead to chronic pain and long-term disability.

27 Apr 2021

Nanobodies neutralize SARS-CoV-2 in pre-clinical model

A team of Australian researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI), the Doherty Institute, and the Kirby Institute have identified neutralizing nanobody cocktails that block the SARS-CoV-2 virus from entering cells in pre-clinical models.

27 Apr 2021

Prior SARS-CoV-2 infection and Pfizer-BioNTech’s COVID-19 vaccine provide similar immunity

Researchers in Israel have conducted a study showing that the immunity provided against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease (COVID-19) – is similar following natural infection or immunization with the Pfizer-BioNTech BNT162b2 vaccine.

26 Apr 2021

Study raises concern about limited immune response of transplant patients after COVID-19 vaccination

A small study from Mayo Clinic researchers raises the concern that some transplant patients may have a limited immune response after being vaccinated for COVID-19 with an mRNA vaccine.

26 Apr 2021

New COVID-19 testing strategy can quicken test results for healthcare workers

Fast turnaround of COVID-19 test results for healthcare workers is critical. Investigators have now developed a COVID-19 testing strategy that maximizes the proportion of negative results after a single round of testing, allowing prompt notification of results.

26 Apr 2021

Ultraviolet C radiation is effective in inactivating SARS-CoV-2 on glass surfaces, a study finds

A team of scientists from the Texas Biomedical Research Institute and UV Innovators, Inc., USA, recently developed an ultraviolet C radiation emitting device called NuvaWave, which is capable of inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on glass surfaces within seconds.

26 Apr 2021

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

However, with the waning of the immune response, it is not clear if these older people respond to the vaccine as well as younger individuals do. A recent study explored this question and found that though the antibody levels were somewhat lower in this group, they were still robust. This is a promising observation.

26 Apr 2021

Could pooled testing really improve COVID-19 transmission management and decrease costs?

Pooled testing for SARS-CoV-2 detection is instrumental for increasing test capacity while decreasing test cost. A team of researchers at Yale School of the Environment determined the barriers to implementing pooled testing in United States laboratories. The study showed that many laboratories use many instruments in their testing procedures, varying in the number of samples each can process.

26 Apr 2021

UT Southwestern reports first cases of Brazilian variant of COVID-19 infection in North Texas

UT Southwestern Medical Center scientists have identified the first cases of the Brazilian variant of COVID-19 infection in North Texas using next-generation sequencing technologies along with PCR testing.

26 Apr 2021

Fighting malaria in 2021: Where are we now and where are we going?

In support of World Malaria Day, News-Medical spoke to Dr. Laurence Slutsker, an internationally recognized expert in malaria, about fighting this disease in 2021.

26 Apr 2021

Efficacy News and Research

Artificial super stool may be a game-changer in the treatment of chronic gut infections

Study examines mRNA COVID-19 vaccine’s effectiveness across age and gender

Can control theory explain differences in virulence and transmission of SARS-CoV-2?

Peptide nucleocapsid vaccine candidate elicits protective T cell immunity against SARS-CoV-2 in vivo

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

Clinical trial to test existing antibiotic for treating serious S. aureus infections begins

Pfizer-BioNTech (BNT162b2) vaccine successfully curbs COVID-19 in Israel

ANTICOV clinical trial to test new treatment for people with mild-to-moderate COVID-19 in Africa

What is the role of nanotechnology in the current COVID-19 outbreak?

Nucleocapsid-based vaccines may prevent SARS-CoV-2 dissemination to distal organs

Study highlights the psychological and social concerns of musculoskeletal trauma patients

Nanobodies neutralize SARS-CoV-2 in pre-clinical model

Prior SARS-CoV-2 infection and Pfizer-BioNTech’s COVID-19 vaccine provide similar immunity

Study raises concern about limited immune response of transplant patients after COVID-19 vaccination

New COVID-19 testing strategy can quicken test results for healthcare workers

Ultraviolet C radiation is effective in inactivating SARS-CoV-2 on glass surfaces, a study finds

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

Could pooled testing really improve COVID-19 transmission management and decrease costs?

UT Southwestern reports first cases of Brazilian variant of COVID-19 infection in North Texas

Fighting malaria in 2021: Where are we now and where are we going?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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