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Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

MedUni Vienna researchers discover genetic cause of a rare disease

Researchers at MedUni Vienna have discovered the genetic cause of a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when they reach school age.

15 Nov 2015

Research identifies liver pathway that contributes to negative effects of high-fat, high-cholesterol junk food diet

It's no secret that a high-fat, high-cholesterol "junk food" diet has been linked to major health problems, including high blood cholesterol and the buildup of plaques in the arteries, known as atherosclerosis.

13 Nov 2015

Johns Hopkins researchers present new healthcare tips from American Heart Association Meeting

Linking digital activity trackers to smartphones and periodically pinging users with personalized texts that urge them to walk more can significantly increase physical activity levels and spark healthy behavior changes, according to findings of a pilot study conducted at Johns Hopkins.

13 Nov 2015

Angina in women linked with abnormal heart blood flow

Chest pain in female-pattern heart disease is linked with abnormal heart blood flow, demonstrated with a drug commonly used to alleviate chest pain patients with coronary artery disease, which was found to be ineffective in patients with moderate female-pattern heart disease, but may offer some relief for sicker patients, a new Cedars-Sinai Heart Institute study shows.

12 Nov 2015

CHOP researchers delay symptoms, extend lifespan in animal model of Batten disease

Researchers have taken a significant step forward in developing gene therapy against a fatal neurodegenerative disease that strikes children. By delivering a working version of a gene to produce a key enzyme that is lacking in Batten disease, the scientists delayed symptoms and extended lifespan in dogs with a comparable disease.

12 Nov 2015

Tocilizumab drug offers potential treatment for patients with polymyalgia rheumatics

A drug approved to treat rheumatoid arthritis, tocilizumab (Actemra, Genentech), is a potential new therapy for patients with polymyalgia rheumatica, according to an open-label, phase II study presented at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals on November 10.

11 Nov 2015

Study: Post hospital syndrome is significant risk factor for patients undergoing elective surgery

A condition known as "post hospital syndrome" (PHS) is a significant risk factor for patients who undergo elective outpatient surgery, a Loyola study has found.

11 Nov 2015

Cotellic (cobimetinib) approved to be used in combination with vemurafenib for melanoma treatment

The U.S. Food and Drug Administration today approved Cotellic (cobimetinib) to be used in combination with vemurafenib to treat advanced melanoma that has spread to other parts of the body or can't be removed by surgery, and that has a certain type of abnormal gene (BRAF V600E or V600K mutation).

10 Nov 2015

New vaccine appears to be more effective in reducing 'bad' LDL cholesterol

A new cholesterol-lowering vaccine leads to reductions in 'bad' LDL cholesterol in mice and macaques, according to research published in Vaccine. The authors of the study, from the University of New Mexico and the National Institutes of health in the United States, say the vaccine has the potential to be a more powerful treatment than statins alone.

10 Nov 2015

Idera begins enrollment in IMO-8400 Phase 2 clinical trial for treatment of dermatomyositis

Idera Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company developing Toll-like receptor (TLR) and RNA therapeutics for patients with cancer and rare diseases, today announced that the company has commenced enrollment in a Phase 2 clinical trial of IMO-8400, an investigational TLR 7, 8 and 9 antagonist, in patients with dermatomyositis. Dermatomyositis is a rare and debilitating inflammatory muscle and skin disease associated with significant morbidity, decreased quality of life and an increased risk of premature death.

10 Nov 2015

Protein sensor for proprioception found

Can you touch a finger to the tip of your nose with your eyes closed? Most of us can, thanks to a sense called proprioception, which tells us where our body parts are relative to each other and our environment. Not surprisingly, this sense is essential for normal movement and balance—walking, for instance.

10 Nov 2015

Australian researchers define key characteristics of metabolically healthy obese

Australian researchers have defined some key characteristics of the metabolically healthy obese -- those obese individuals who remain free from type 2 diabetes and other disorders that usually associate with obesity. Their findings have implications for the treatment of type 2 diabetes, insulin resistance and obesity.

10 Nov 2015

New funding for Centenary's life saving research

The Centenary Institute has welcomed the Federal Government’s announcement of funding for 9 new and innovative medical research projects via the latest round of NHMRC grant rounds funding, officially confirmed today.

9 Nov 2015

Armaron Bio starts Phase 2 trial for novel lead candidate drug for heart failure

Armaron Bio, a Melbourne-based drug development company focused on heart failure and other diseases, is pleased to announce that it has begun its Phase II clinical trial for NP202, its novel lead candidate drug for heart failure.

9 Nov 2015

Combatting viral and bacterial lung infections with volatile anesthetics: an interview with Dr Chakravarthy

Inhaled anesthetics are fairly common all over the world for minor and extensive surgical procedures in patients of all age groups. In the olden days when anesthesia was first developed, ether was the first inhaled anesthetic. That has been replaced, with the more recent discoveries of sevoflurane, isoflurane, and desflurane.

9 Nov 2015

Sleep loss reduces insulin sensitivity, increases diabetes risk

A new study by the University of Colorado shows that the longer people are awake during the time their biological clock is telling them to sleep the worse their sensitivity to insulin, which is a precursor to diabetes.

6 Nov 2015

New protein supplement lowers cholesterol, prevents osteoporosis

Scientists developed a supplement to maintain optimal health that contributes to the growth and development of children and adolescents. It also prevents osteoporosis and certain cancers such as breast and prostate.

5 Nov 2015

Doing exercise during puberty can improve bone health in adulthood, Spanish study confirms

Osteoporosis is a serious health issue that mainly affects postmenopausal women. Now, a Spanish study has confirmed that doing exercise during puberty can improve bone health in adulthood. In this scope, sports such as football, handball and basketball are better than others such as swimming.

5 Nov 2015

International research project examines effectiveness of tried and tested medicines for different diseases

The Medical University of Vienna is coordinating an international research project, which investigates the effectiveness of tried and tested medicines for the treatment of some of the heaviest burdens of our modern society including diseases such as cancer, diabetes and cardiovascular diseases. One molecule that these disorders have in common is a receptor known as the calcium-sensing receptor (CaSR), which is the molecular starting point of this project.

4 Nov 2015

Muscle News and Research

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

MedUni Vienna researchers discover genetic cause of a rare disease

Research identifies liver pathway that contributes to negative effects of high-fat, high-cholesterol junk food diet

Johns Hopkins researchers present new healthcare tips from American Heart Association Meeting

Angina in women linked with abnormal heart blood flow

CHOP researchers delay symptoms, extend lifespan in animal model of Batten disease

Tocilizumab drug offers potential treatment for patients with polymyalgia rheumatics

Study: Post hospital syndrome is significant risk factor for patients undergoing elective surgery

Cotellic (cobimetinib) approved to be used in combination with vemurafenib for melanoma treatment

New vaccine appears to be more effective in reducing 'bad' LDL cholesterol

Idera begins enrollment in IMO-8400 Phase 2 clinical trial for treatment of dermatomyositis

Protein sensor for proprioception found

Australian researchers define key characteristics of metabolically healthy obese

New funding for Centenary's life saving research

Armaron Bio starts Phase 2 trial for novel lead candidate drug for heart failure

Combatting viral and bacterial lung infections with volatile anesthetics: an interview with Dr Chakravarthy

Sleep loss reduces insulin sensitivity, increases diabetes risk

New protein supplement lowers cholesterol, prevents osteoporosis

Doing exercise during puberty can improve bone health in adulthood, Spanish study confirms

International research project examines effectiveness of tried and tested medicines for different diseases

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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