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Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil suggest that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits SARS-CoV-2 replication as well as the exacerbated inflammatory response that leads to death in many patients with severe COVID-19.

21 Oct 2022

Researchers assess the dependence potential and abuse liability of delta-8-THC

One is an illegal drug found in marijuana while the other is marketed as a safe herbal alternative. But the claimed differences between them aren't backed by science, a group of UConn researchers report on Nov. 1 in Drug and Alcohol Dependence.

21 Oct 2022

Breakthrough discovery is a 'major step forward' in understanding cervical cancer

Scientists have discovered that cervical cancer can be divided into two distinct molecular subgroups – one far more aggressive than the other – as part of the largest 'omics' study of its kind, led by researchers at UCL and the University of Southampton.

21 Oct 2022

New research could have major implications for minimally invasive, robotically delivered brain surgery

The early-stage research tested the delivery and safety of the new implantable catheter design in two sheep to determine its potential for use in diagnosing and treating diseases in the brain.

21 Oct 2022

Duke biomedical engineers develop a two-pronged approach to treating pancreatic cancer

Biomedical engineers at Duke University have demonstrated the most effective treatment for pancreatic cancer ever recorded in mouse models.

21 Oct 2022

Multiple research platforms identify environmental chemical agents that promote intestinal inflammation

Inflammatory bowel disease (IBD), a condition characterized by chronic gastrointestinal inflammation, is becoming increasingly common in industrialized countries.

21 Oct 2022

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Pseudomonas aeruginosa (P.a.) are resistant to most antibiotics and cause life-threatening infections of wounds or the lungs.

21 Oct 2022

Parental exercise improves whole-body glucose metabolism in offspring, study finds

A mouse study by Kristin Stanford, a physiology and cell biology researcher with The Ohio State University College of Medicine at the Wexner Medical Center, provides new ways to determine how maternal and paternal exercise improve metabolic health of offspring.

20 Oct 2022

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

In a recent study posted to the medRxiv* preprint server, University of Arizona researchers assessed the relationship between antibody responses and analgesic usage after coronavirus disease 2019 (COVID-19) vaccination.

20 Oct 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

Infancy acid suppression and antibiotic use are associated with celiac disease

Researchers determine whether exposure to certain prescriptions after the first six months of life was associated with a diagnosis of celiac disease.

20 Oct 2022

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

20 Oct 2022

Amygdala may also be to blame for overeating, research finds

A region of the brain called the amygdala is responsible for powerful emotions like fear. Now, researchers have found the amygdala may also be to blame for overeating.

20 Oct 2022

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.

20 Oct 2022

UMass Amherst genetic research provides a new model for investigating diseases related to circadian rhythm disruptions

University of Massachusetts Amherst research into genetic mutations that affect circadian rhythms offers new insight into the rest-wake cycle and provides a new model for investigating human disease and ultimately developing medical treatments.

20 Oct 2022

KHN’s ‘What the Health?’: Biden hits the road to sell Democrats’ record

What do pandemic preparedness, mental health care services, and over-the-counter hearing aids have in common? They are all things President Joe Biden touted on the campaign trail this week as he tries to maintain Democrats' majorities in Congress in the midterm elections Nov. 8.

20 Oct 2022

Study identifies gene mutations that impact radiation resistance and sensitivity

A new Northwestern Medicine study identifies common and rare gene mutations that impact radiation resistance and sensitivity, an important step toward providing more individualized and effective radiotherapy for patients with cancer.

20 Oct 2022

AGA releases evidence-based guidelines that recommend new obesity medications and lifestyle changes

Diet and exercise fail for most adults who try to lose weight in the long-term. Today the American Gastroenterological Association (AGA) released new evidence-based guidelines strongly recommending that these patients with obesity use recently approved medications paired with lifestyle changes.

20 Oct 2022

Survey shows healthcare affordability remains on the ballot and could have a big influence on elections

Nearly nine in 10 Americans say a candidate's plan for reducing healthcare costs will be an important consideration in determining their vote, and almost 40% of them, or an estimated 100 million Americans, say it could even make them cross party lines in the upcoming midterm elections, according to a new poll from West Health and Gallup.

20 Oct 2022

Two small molecules reverse pancreatic acinar ductal metaplasia

Pancreatic cancer often lurks as a silent disease. With no known symptoms, it can progress undetected and spread to other organs.

20 Oct 2022

Drugs News and Research

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Researchers assess the dependence potential and abuse liability of delta-8-THC

Breakthrough discovery is a 'major step forward' in understanding cervical cancer

New research could have major implications for minimally invasive, robotically delivered brain surgery

Duke biomedical engineers develop a two-pronged approach to treating pancreatic cancer

Multiple research platforms identify environmental chemical agents that promote intestinal inflammation

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Parental exercise improves whole-body glucose metabolism in offspring, study finds

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

Infancy acid suppression and antibiotic use are associated with celiac disease

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Amygdala may also be to blame for overeating, research finds

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

UMass Amherst genetic research provides a new model for investigating diseases related to circadian rhythm disruptions

KHN’s ‘What the Health?’: Biden hits the road to sell Democrats’ record

Study identifies gene mutations that impact radiation resistance and sensitivity

AGA releases evidence-based guidelines that recommend new obesity medications and lifestyle changes

Survey shows healthcare affordability remains on the ballot and could have a big influence on elections

Two small molecules reverse pancreatic acinar ductal metaplasia

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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