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Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

Toxic protein may be the cause of muscular dystrophy and arhinia

Balancing care responsibilities with paid work provides working caregivers with emotional benefits

19 Feb 2023

Vaccination rate remains unchanged but misinformation about flu and Covid-19 stays

Although the public had been alerted that this winter could be a potentially bad flu season, barely half of Americans said in January that they had received a flu shot, a vaccination level unchanged in a representative national panel from the comparable period last year, according to a new Annenberg Science Knowledge (ASK) survey by the Annenberg Public Policy Center of the University of Pennsylvania.

17 Feb 2023

One-third of stroke survivors experience depression

According the American Stroke Association, a division of the American Heart Association, depression is a common experience for stroke survivors.

17 Feb 2023

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

Canagliflozin ameliorates heart function in HFpEF rats partly by regulating ferroptosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been found to ameliorate major adverse cardiovascular events in patients with heart failure with preserved ejection fraction (HFpEF), but the exact mechanism is unknown.

17 Feb 2023

ACC Cardiovascular Summit to focus on increased role of telehealth post COVID-19

The American College of Cardiology's Cardiovascular Summit will feature several poster presentations on the increased role of telehealth in cardiovascular care since the COVID-19 pandemic.

16 Feb 2023

Research looks to determine prevalence of organ impairment in long-COVID patients

In a recent study published in the Journal of the Royal Society of Medicine, researchers assessed the association of long coronavirus disease (COVID) with multiple organ dysfunction.

16 Feb 2023

Non-invasive FFRCT offers greater accuracy in heart disease diagnosis than other traditional tests

As a patient with a family history of heart disease, Karen Moore has always been diligent about monitoring her heart health.

16 Feb 2023

How does alcohol affect blood pressure?

Drinking is part of human society worldwide. However, alcohol consumption has been strongly linked to human diseases, including dementia, liver cirrhosis, and neurological conditions. A recent research paper examined whether drinking was related to hypertension, the root factor in morbidity and mortality caused by cardiovascular disease (CVD).

16 Feb 2023

Variations in long COVID symptoms and diagnostic experiences among racial, ethnic groups

Black and Hispanic Americans appear to experience more symptoms and health problems related to long COVID, a lay term that captures an array of symptoms and health problems, than white people, but are not as likely to be diagnosed with the condition, according to new research funded by the National Institutes of Health.

16 Feb 2023

Heart News and Research

Genome editing prevents hypertrophic cardiomyopathy in mice

Are SGLT2 inhibitors the next blockbuster drug?

Toxic protein may be the cause of muscular dystrophy and arhinia

Vaccination rate remains unchanged but misinformation about flu and Covid-19 stays

One-third of stroke survivors experience depression

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Canagliflozin ameliorates heart function in HFpEF rats partly by regulating ferroptosis

ACC Cardiovascular Summit to focus on increased role of telehealth post COVID-19

Research looks to determine prevalence of organ impairment in long-COVID patients

Non-invasive FFRCT offers greater accuracy in heart disease diagnosis than other traditional tests

How does alcohol affect blood pressure?

Variations in long COVID symptoms and diagnostic experiences among racial, ethnic groups

Similar genes may lead to different patterns of fat distribution in women

Novel experimental platform optically records neuronal activity during brain-wide fMRI in rodents

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

She sued a hospital and lost — but felt she’d won

As covid grabbed the world’s attention, Texas’ efforts to control TB slipped

Natural decline in insulin resistance during mid-adolescence may stop, reverse arterial stiffness progression

Sleep irregularity may increase the risk for atherosclerosis

Increasing numbers of cancer survivors at high risk for cardiovascular disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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