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FDA grants permission to assess safety of investigational drug for Alzheimer's disease in humans

Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration that testing in humans may proceed for an investigational new drug for Alzheimer's disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

28 Dec 2016

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Using a mouse model, scientists from the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology and a number of other institutes have identified a sugar molecule that reduced the inflammatory response and progress of emphysema, a common component of chronic obstructive pulmonary disease (COPD).

27 Dec 2016

Potential drug could become first effective treatment option for Prader-Willi syndrome

Duke Health researchers have identified a drug-like small molecule that, in animal experiments, appears to be an effective treatment for a genetic disorder called Prader-Willi syndrome.

27 Dec 2016

New research points to lncRNA's key role in helping control cellular processes

Scientific research over the past decade has concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent, a vast universe of non-coding genetic material previously dismissed as nothing more than 'junk.'

27 Dec 2016

Johns Hopkins scientists find link between sleep/wake cycles and core body temperature

A clump of just a few thousand brain cells, no bigger than a mustard seed, controls the daily ebb and flow of most bodily processes in mammals -- sleep/wake cycles, most notably.

23 Dec 2016

Researchers develop novel membranes whose selectivity can be tuned dynamically with light

Researchers of Karlsruhe Institute of Technology (KIT) and Uni-versität Hannover developed novel membranes, whose selectivity can be switched dynamically with the help of light.

23 Dec 2016

Making muscles burn more fat and less glucose could cause diabetes, say researchers

Making muscles burn more fat and less glucose can increase exercise endurance, but could simultaneously cause diabetes, says a team of scientists from Baylor College of Medicine and other institutions.

22 Dec 2016

TSRI scientists shed light on how antiviral drug stops influenza infections

A new study led by scientists at The Scripps Research Institute (TSRI) is the first to show exactly how the drug Arbidol stops influenza infections. The research reveals that Arbidol stops the virus from entering host cells by binding within a recessed pocket on the virus.

22 Dec 2016

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand.

22 Dec 2016

A Chain of Life for a Rare Neurodegenerative Disease

Researchers in Japan have improved a potential treatment for a rare genetic disease, decreasing its negative toxic effects by threading it onto a dumb-bell-shaped chain and holding it in place until it reaches its target.

22 Dec 2016

New research offers valuable insight for developing more effective drugs to treat IBD

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis.

22 Dec 2016

Princeton researchers employ light to activate new reactivity in existing enzymes

Enzymes are nature's tools for catalyzing life's essential reactions. Though unrivaled in their efficiency and selectivity, enzymes only carry out a narrow range of natural reactions, limiting their usefulness in modern organic synthesis.

21 Dec 2016

Researchers find accumulation of tumor suppressor in liver after food withdrawal

Tumor suppressors stop healthy cells from becoming cancerous. Researchers from Charité - Universitätsmedizin Berlin, the Medical University of Graz and the German Institute of Human Nutrition in Potsdam-Rehbruecke have found that p53, one of the most important tumor suppressors, accumulates in liver after food withdrawal.

21 Dec 2016

Molecule News and Research

FDA grants permission to assess safety of investigational drug for Alzheimer's disease in humans

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Potential drug could become first effective treatment option for Prader-Willi syndrome

New research points to lncRNA's key role in helping control cellular processes

Johns Hopkins scientists find link between sleep/wake cycles and core body temperature

Researchers develop novel membranes whose selectivity can be tuned dynamically with light

Making muscles burn more fat and less glucose could cause diabetes, say researchers

TSRI scientists shed light on how antiviral drug stops influenza infections

Generative AAE can be radically new way to discover drugs on demand

A Chain of Life for a Rare Neurodegenerative Disease

New research offers valuable insight for developing more effective drugs to treat IBD

Princeton researchers employ light to activate new reactivity in existing enzymes

Researchers find accumulation of tumor suppressor in liver after food withdrawal

RAGE regulates key signaling pathway that promotes acute and chronic inflammation

Researcher develops new method to accurately identify elusive molecules

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Dual treatment strategies lengthen lives of mice with skin cancer

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

Scientists detail structure of molecule implicated in Alzheimer's disease

Breast cancer patient finds new hope with potentially revolutionary treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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