Oxygen News and Research

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Positive data from Lyxumia study on type 2 diabetes presented at ADA 2011

Sanofi announced today data from four studies of its once-daily GLP-1 receptor agonist Lyxumia that is in Phase III clinical development, including data that demonstrates positive results in type 2 diabetes patients not at goal on oral therapies or with basal insulin.

27 Jun 2011

Transcatheter valve replacement safe and effective alternative to open-heart surgery

An innovative approach for implanting a new aortic heart valve without open-heart surgery is being offered at Rush University Medical Center to patients with severe aortic stenosis who are at high-risk or not suitable candidates for open heart valve replacement surgery.

27 Jun 2011

FDA recommends conservative dosing guidelines for ESAs to treat anemia in patients with CKD

The U.S. Food and Drug Administration today recommended more conservative dosing guidelines for Erythropoiesis-Stimulating Agents (ESAs) when used to treat anemia in patients with chronic kidney disease (CKD) because of the increased risks of cardiovascular events such as stroke, thrombosis, and death.

27 Jun 2011

Positive preliminary findings from ATI's neurostimulation system study on cluster headache

Autonomic Technologies, Inc. (ATI), the developer of a novel miniaturized implantable system for severe headaches, today announced positive preliminary findings from a study evaluating the safety and efficacy of the company's investigational neurostimulation system for the treatment of cluster headache.

27 Jun 2011

Protein globin E helps avian eyes 'breathe' and contributes to visual acuity

Say what you will about bird brains, but our feathered friends sure have us -- and all the other animals on the planet -- beat in the vision department, and that has a bit to do with how their brains develop.

24 Jun 2011

Stresses can change gene expression without DNA sequence change

None of us are strangers to stress of various kinds. It turns out the effects of all those stresses can change the fate of future generation, influencing our very DNA without any change to the underlying sequence of As, Gs, Ts and Cs. Now, researchers reporting in the June 24th issue of Cell, a Cell Press publication, have new evidence that helps to explain just how these epigenetic changes really happen.

24 Jun 2011

Nine young clinical investigators earn recognition from Damon Runyon Cancer Research Foundation

The Damon Runyon Cancer Research Foundation named five new Damon Runyon Clinical Investigators at its spring 2011 Clinical Investigator Award Committee review.

22 Jun 2011

Pycnogenol, CoQ10 combination boost heart function

A recent study published in Panminerva Medica reveals that a Pycnogenol and Coenzyme Q10 combination taken by stable heart failure patients as an adjunct to medical treatment naturally strengthens the heart, increasing the blood volume ejected with each beat.

22 Jun 2011

Strawberries improve antioxidant capacity of blood

A group of volunteers ate half a kilo of strawberries every day for two weeks to demonstrate that eating this fruit improves the antioxidant capacity of blood. The study, carried out by Italian and Spanish researchers, showed that strawberries boost red blood cells' response to oxidative stress, an imbalance that is associated with various diseases.

21 Jun 2011

Genetic biomarker may help identify patients at increased risk of bypass surgery

Outcomes of bypass surgery to repair blocked arteries in the legs tend to be better in the roughly one-in-five people who have inherited a specific genetic variation from both parents, according to a study presented at the late-breaking clinical trials session of the Vascular Annual Meeting in Chicago on June 18, 2011.

20 Jun 2011

Short warm-ups permit greater cycling performance

Coaches, physiologists and athletes alike will attest to the importance of warming up before athletic competition. Warming up increases muscle temperature, accelerates oxygen uptake kinetics and increases anaerobic metabolism, all of which enhance performance.

18 Jun 2011

First artificial lung transplantation in toddler performed at St. Louis Children's Hospital

Two-year-old Owen Stark came to St. Louis Children's Hospital in the summer of 2010 near death from heart failure and dangerously high blood pressure in his lungs.

17 Jun 2011

'Blue baby' study sheds light on basic biology

A newborn described as a "happy blue baby" because of her bluish skin color but healthy appearance made a small mark in medical history when one of her physicians discovered something new in her genes-the hemoglobin Toms River mutation.

17 Jun 2011

Evidence-based practice guidelines for prevention and treatment of frostbite

Frostbite can be a minor injury or a life-threatening condition. In the June issue of Wilderness & Environmental Medicine, a panel of experts has published evidence-based practice guidelines issued by the Wilderness Medical Society (WMS) for the prevention and treatment of frostbite to guide clinicians and disseminate knowledge about best practices.

16 Jun 2011

Healthy diet, antioxidants, critical nutrients and activities may provide the foundation to youthful living

As the baby boomer generation continues to increase in age, so does its passion to remain youthful, both inside and out. Beating the clock is now a multi-faceted, science-driven industry. From its age-old quests to find the elixir of life, to modern exploration of how microcellular activity contributes to metabolic breakdown, scientific research continues to advance its goals to enhance bodily energy, vigour and performance, and fade or stall the visible signs of aging.

16 Jun 2011

New method uses ICP-MS system to identify radioactive elements in environment

Agilent Technologies Inc. today announced it has developed a new method to identify radioactive iodine using inductively coupled plasma mass spectrometry (ICP-MS). The method will first be used by Gakushuin University in Japan, with a donated Agilent 7700 ICP-MS System.

15 Jun 2011

Sangart commences MP4OX Phase 2b study in acute traumatic injury

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic tissues through targeted oxygen and other gas delivery, today announced the initiation of a Phase 2b study designed to evaluate the efficacy and safety of MP4OX treatment plus standard of care in severely injured trauma patients with lactic acidosis due to hemorrhagic shock.

15 Jun 2011

Untreated obstructive sleep apnea can reduce work productivity

Large corporations could save millions of dollars in lost productivity by screening and treating high-risk employees for obstructive sleep apnea, suggests a research abstract that will be presented Monday, June 13, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC.

14 Jun 2011

Severe sleep apnea increases risk of gestational diabetes and preterm birth in pregnant women

Sleep apnea is associated with an increased risk of adverse pregnancy outcomes, suggests a research abstract that will be presented Monday, June 13, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC (APSS).

13 Jun 2011

MCMs mediate crosstalk between cell division machinery and oxygen-sensing protein

Cells grow abundant when oxygen is available, and generally stop when it is scarce. Although this seems straightforward, no direct link ever has been established between the cellular machinery that senses oxygen and that which controls cell division.

13 Jun 2011

Oxygen News and Research

Positive data from Lyxumia study on type 2 diabetes presented at ADA 2011

Transcatheter valve replacement safe and effective alternative to open-heart surgery

FDA recommends conservative dosing guidelines for ESAs to treat anemia in patients with CKD

Positive preliminary findings from ATI's neurostimulation system study on cluster headache

Protein globin E helps avian eyes 'breathe' and contributes to visual acuity

Stresses can change gene expression without DNA sequence change

Nine young clinical investigators earn recognition from Damon Runyon Cancer Research Foundation

Pycnogenol, CoQ10 combination boost heart function

Strawberries improve antioxidant capacity of blood

Genetic biomarker may help identify patients at increased risk of bypass surgery

Short warm-ups permit greater cycling performance

First artificial lung transplantation in toddler performed at St. Louis Children's Hospital

'Blue baby' study sheds light on basic biology

Evidence-based practice guidelines for prevention and treatment of frostbite

Healthy diet, antioxidants, critical nutrients and activities may provide the foundation to youthful living

New method uses ICP-MS system to identify radioactive elements in environment

Sangart commences MP4OX Phase 2b study in acute traumatic injury

Untreated obstructive sleep apnea can reduce work productivity

Severe sleep apnea increases risk of gestational diabetes and preterm birth in pregnant women

MCMs mediate crosstalk between cell division machinery and oxygen-sensing protein

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