Protein C News and Research

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Exploring the effects of dietary fiber on gut microbiome and inflammatory diseases

Researchers reviewed how dietary fibers modulate the composition and function of gut microbiota.

2 Dec 2022

Novel biosensor enhances performance of home-based continuous glucose monitoring

Home-based continuous glucose monitoring for diabetics up to now has had to trade ease of use, low cost, and portability for a somewhat lower sensitivity - and thus accuracy - compared to similar systems in clinics or hospitals.

2 Dec 2022

CRC 1361 at JGU continues to achieve excellence in DNA repair and genome stability research

The German Research Foundation (DFG) announced the prolongation of the Collaborative Research Center (CRC) 1361: "Regulation of DNA Repair and Genome Stability" for an additional four years.

2 Dec 2022

The effect of ubiquitination on SARS-CoV-2 infection and patient prognosis

A recent Clinical and Translational Medicine study utilized several published public datasets to evaluate the biological characteristics associated with the ubiquitination of patients infected with SARS-CoV-2.

2 Dec 2022

The prevalence and risk factors of pediatric post-COVID in a population-based sample

Researchers compared seropositive and seronegative children between the ages of six months and 17 years to assess the risk factors and prevalence of persistent symptoms of post-COVID syndrome.

2 Dec 2022

Antibody responses engendered by maternal SARS-CoV-2 vaccination following initial and booster doses in maternal circulation and breastmilk

Researchers investigated passive immunization of the fetus and neonates by evaluating the antibody responses elicited by primary and booster doses of maternal SARS-CoV-2 vaccination.

2 Dec 2022

Study implicates gut microbiome health in Parkinson's disease

A new study published in the journal Nature Communications discusses the links between this condition that affects the brain and changes in the gut microbiome that may predate brain changes.

1 Dec 2022

First-in-humans test provides promising results for a broadly neutralizing antibody HIV vaccine

A Phase 1 clinical trial provides promising results for a broadly neutralizing antibody (bnAb) HIV vaccine, according to a new study.

1 Dec 2022

Human T cell immunity is coping with mutations in SARS-CoV-2 variants of concern

Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research.

1 Dec 2022

Prior infection and vaccination protects against severe outcomes from SARS-CoV-2 Omicron infection

Previous infection with SARS-CoV-2 and booster vaccination protect against ICU admission and mortality following infection with the Omicron variant.

1 Dec 2022

Two experimental mRNA vaccines highly effective in reducing malaria infection and transmission

Malaria is found in more than 90 countries around the world, causing 241 million cases and an estimated 627,000 deaths every year.

1 Dec 2022

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

New, nanotech-based strategy could enable safe, long-term treatment for autoimmune diseases

Scientists at Scripps Research have reported success in initial tests of a new, nanotech-based strategy against autoimmune diseases.

1 Dec 2022

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

1 Dec 2022

Scientists discover new potential mechanism for vision loss

Visual cells in the human retina may not simply die in some diseases, but are mechanically transported out of the retina beforehand.

1 Dec 2022

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Researchers mutated the SARS-CoV-2 spike protein's trimeric structure to design a novel prefusion S antigen, S2D14.

1 Dec 2022

Detection of filoviruses by the innate immune system

In a new study, researchers examined how the innate immune system detects filoviruses.

1 Dec 2022

Study compares the performance of two most popular AMD drugs

A pilot, "look-back" study of information about 106 patients with "wet" age-related macular degeneration (AMD) treated at the Wilmer Eye Institute at Johns Hopkins Medicine has revealed that nearly half of patients treated with aflibercept could safely stop eye injection therapy after one year without further vision loss.

30 Nov 2022

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

A change in the DNA code (mutation) of a gene that plays a key role in the brain's immune defenses may prevent related cells from clearing away protein-filled clumps, a new study in mice shows.

30 Nov 2022

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

Latest research findings show that vaccine-elicited neutralizing antibodies against SARS-CoV-2 are mostly directed against one of the two main domains of the viral entry machinery.

30 Nov 2022

Protein C News and Research

Exploring the effects of dietary fiber on gut microbiome and inflammatory diseases

Novel biosensor enhances performance of home-based continuous glucose monitoring

CRC 1361 at JGU continues to achieve excellence in DNA repair and genome stability research

The effect of ubiquitination on SARS-CoV-2 infection and patient prognosis

The prevalence and risk factors of pediatric post-COVID in a population-based sample

Antibody responses engendered by maternal SARS-CoV-2 vaccination following initial and booster doses in maternal circulation and breastmilk

Study implicates gut microbiome health in Parkinson's disease

First-in-humans test provides promising results for a broadly neutralizing antibody HIV vaccine

Human T cell immunity is coping with mutations in SARS-CoV-2 variants of concern

Prior infection and vaccination protects against severe outcomes from SARS-CoV-2 Omicron infection

Two experimental mRNA vaccines highly effective in reducing malaria infection and transmission

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

New, nanotech-based strategy could enable safe, long-term treatment for autoimmune diseases

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

Scientists discover new potential mechanism for vision loss

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Detection of filoviruses by the innate immune system

Study compares the performance of two most popular AMD drugs

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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