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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Gene mutation linked to MEF2C haploinsufficiency syndrome

A collaboration between scientists at the Medical University of South Carolina and clinicians at the Greenwood Genetic Center has yielded new findings about how a particular gene might regulate brain development.

19 May 2020

DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

In Germany about 18 million people suffer from non-alcoholic fatty liver. The causes of this disease are manifold and include environmental as well as genetic factors.

19 May 2020

SWOG scientists to deliver online presentations at ASCO20 Virtual Scientific Program

Researchers from SWOG, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, will make 31 presentations as part of the ASCO20 Virtual Scientific Program, the online annual meeting of the American Society of Clinical Oncology (ASCO), which runs May 29-31.

19 May 2020

Gene variants can increase risk of schizophrenia, shows study

Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren's syndrome, according to findings published in the journal Nature.

19 May 2020

Researchers create more crucial reagents for use in COVID-19 tests

Researchers in Warwick Medical School at the University of Warwick have developed a way to create more crucial reagents for use in COVID-19 tests that could also provide enhancements to the use of, and production of, future tests.

19 May 2020

Multi-institutional clinical trial sheds new light on non-responsive tumors

Over the last decade, enzalutamide and similar drugs have led to significant tumor control and increased survival time for men who have metastatic prostate cancer that continues to grow despite treatments to reduce male hormone levels.

19 May 2020

New animal model for COVID-19

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage the world, scientists are frantically searching for a vaccine or new drug that will effectively counter the lethal effects of the virus that leads to COVID-19 disease.

19 May 2020

Study shows how RNA editing affects the replication of COVID-19 virus

Two human deaminase enzymes edit the RNA of the SARS-CoV-2 virus when it enters a patient's body, with implications for the evolution of the virus and the spread of the infection, according to a new study.

19 May 2020

Researchers identify determining factor in luminal cancer cells

The Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona, led by ICREA researcher Raúl Méndez, has published a study in the journal Science Advances that has identified a key factor in the development of luminal breast cancer.

18 May 2020

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of multiple studies of several different types of cancers.

18 May 2020

New analysis links DNA variations to risks of specific breast cancer subtypes

An analysis of genetic studies covering 266,000 women has revealed 32 new sites on the human genome where variations in DNA appear to alter the risks of getting breast cancer.

18 May 2020

SMART researchers awarded NMRC funding to develop rapid paper-based COVID-19 tests

Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, has received a grant from the National Medical Research Council COVID-19 Research fund for the acceleration of research and development of rapid paper-based serological and diagnostic tests for COVID-19.

18 May 2020

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

IDT opens new manufacturing facility to expand capacity of COVID-19 products

Integrated DNA Technologies, a leading comprehensive genomics solutions provider, announced the opening of its new manufacturing facility located in the Research Triangle Park in North Carolina.

From Integrated DNA Technologies 18 May 2020

Genome-wide pattern found in glioblastoma tumors predicts patients' life expectancy

For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM) -- the most common and the most aggressive brain cancer -- has simply been age at diagnosis.

15 May 2020

Study finds high variability in access to, and quality of, bone density scanning facilities worldwide

There is high variability in access to, and quality of, bone density scanning facilities worldwide, according to a landmark global study carried out at the Medical Research Council Lifecourse Epidemiology Unit in collaboration with the International Osteoporosis Foundation and the International Society for Clinical Densitometry.

15 May 2020