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Malaria parasites’ decision making influenced by fatty molecule in human blood

Depletion of a fatty molecule in human blood propels malaria parasites to stop replicating and causing illness in people and instead to jump ship to mosquitoes to continue the transmission cycle, according to a new study by an international research team.

9 Nov 2017

Parity laws may not fully address affordability for patients needing cancer drugs

State laws designed to ensure that the pill form of cancer drugs is not more costly than treatments given through an infusion in a clinic or hospital have had a mixed impact on patients' pocketbooks, according to University of North Carolina Lineberger Comprehensive Cancer Center researchers.

9 Nov 2017

Scientific Statement captures evolving understanding of microvascular complications related to diabetes

The Endocrine Society issued a new Scientific Statement today examining how diabetes damages the body's smallest blood vessels as well as how the condition affects the body's natural repair processes designed to protect the eyes, kidneys, nerves and other organs.

9 Nov 2017

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a cancer patient will benefit from certain immunotherapies, according to a study published in Nature.

9 Nov 2017

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

An analysis of the medical records of patients treated at Massachusetts General Hospital (MGH) for an often-mysterious condition involving damage to small nerve fibers supports the hypothesis that some cases are caused by autoimmune disease and also identifies the first effective treatment option.

9 Nov 2017

Researchers catch killer cells red-handed in the act of microbial murder

Immune cells called "killer cells" target bacteria invading the body's cells, but how do they do this so effectively? Bacteria can quickly evolve resistance against antibiotics, yet it seems they have not so readily been able to evade killer cells. This has caused researchers to become interested in finding out the exact mechanism that killer cells use to destroy bacterial invaders.

9 Nov 2017

Video provides new look at natural process of platelet-driven blood clot contraction

The first view of the physical mechanism of how a blood clot contracts at the level of individual platelets is giving researchers from the Perelman School of Medicine at the University of Pennsylvania a new look at a natural process that is part of blood clotting.

9 Nov 2017

Researchers discover mechanism behind skin inflammation in eczema

Publishing online this week in Cell Host & Microbe, researchers at Johns Hopkins report the discovery of a key underlying immune mechanism that explains why to how our skin becomes inflamed from conditions such as atopic dermatitis, more commonly known as eczema. Toxin-producing bacteria on the surface of our skin induces a protein that causes our own cells to react and cause inflammation.

8 Nov 2017

German scientists develop new nuclear medicine test to identify kidney transplant infection

German scientists have developed a novel nuclear medicine test that can determine whether a kidney transplant patient has developed infection in the transplanted tissue.

8 Nov 2017

Vitamin D deficiency linked to decreased likelihood of successful pregnancy in women with PCOS

Vitamin D may play a key role in helping some women seeking treatment for polycystic ovary syndrome (PCOS)-related infertility get pregnant.

7 Nov 2017

Penn Medicine to conduct Northeast’s first clinical trial of uterine transplants

Penn Medicine will conduct the Northeast's first clinical trial of uterine transplants, to provide women with Uterine Factor Infertility (UFI) - an irreversible form of female infertility that affects as many as 5 percent of women worldwide and 50,000 women in the United States - with a new path to parenthood.

7 Nov 2017

Study finds mislabeling in nearly 70% of cannabidiol products sold online

In recent years, there has been an increased interest in the medicinal use of Cannabidiol (CBD), a chemical that naturally occurs the in cannabis plant (aka "marijuana"). There is interest in CBD as a medicine because there is some evidence that it has medical benefits,

7 Nov 2017

Moderate to vigorous intensity physical activity associated with lower risk of death in older women

Lack of exercise or physical activity is estimated to cause as many deaths each year as smoking. Current guidelines recommend at least 150 minutes a week of moderate intensity physical activity, or 75 minutes a week of vigorous-intensity aerobic physical activity (or a combination of the two), and muscle-strengthening exercises two or more days a week.

7 Nov 2017

Roundworms may provide new clues to nicotine dependence

Researchers at the University of Michigan Life Sciences Institute found that a previously dismissed genetic mechanism may contribute to nicotine dependence, and to the withdrawal effects that can make quitting smoking so difficult.

7 Nov 2017

Research shows high risk for cardiovascular and kidney disease in people with HIV

HIV patients and their doctors are urged to be more aware of the additional health risks associated with treated HIV infection. This follows new research that shows HIV patients at high risk for a heart attack or stroke are also at substantially greater risk for chronic kidney disease and vice versa.

7 Nov 2017

Research reveals impact of helpful strain of bacteria on infants’ digestive tract

Some of the first living things to greet a newborn baby do a lot more than coo or cuddle. In fact, they may actually help the little one's digestive system prepare for a lifetime of fighting off dangerous germs.

7 Nov 2017

Immune system plays surprising role in the aftermath of heart attacks, study finds

A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The research could lead to new therapeutic strategies for heart disease.

7 Nov 2017

Fat hormone associated with NASH may be effective target for therapeutic intervention

The rising obesity epidemic has brought with it an army of maladies. One, in particular, is threatening to outpace many of the disorders that accompany obesity, in terms of occurrence and severity: nonalcoholic fatty liver disease.

7 Nov 2017

UofL researchers help discover new autoimmune disease that causes kidney failure

Researchers at the University of Louisville were part of a group that discovered an insidious new autoimmune disease that causes kidney failure.

3 Nov 2017

ACADIA Pharmaceuticals announces results from Phase II study of antipsychotic in Alzheimer's disease psychosis

ACADIA Pharmaceuticals Inc., a biopharmaceutical company focused on the development and commercialization of innovative medicines to address unmet medical needs in central nervous system (CNS) disorders, today announced the presentation of data from the Phase II -019 Study of pimavanserin in Alzheimer's disease psychosis at the 10th Clinical Trials on Alzheimer's Disease meeting in Boston.

3 Nov 2017

Medical School News and Research

Malaria parasites’ decision making influenced by fatty molecule in human blood

Parity laws may not fully address affordability for patients needing cancer drugs

Scientific Statement captures evolving understanding of microvascular complications related to diabetes

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

Researchers catch killer cells red-handed in the act of microbial murder

Video provides new look at natural process of platelet-driven blood clot contraction

Researchers discover mechanism behind skin inflammation in eczema

German scientists develop new nuclear medicine test to identify kidney transplant infection

Vitamin D deficiency linked to decreased likelihood of successful pregnancy in women with PCOS

Penn Medicine to conduct Northeast’s first clinical trial of uterine transplants

Study finds mislabeling in nearly 70% of cannabidiol products sold online

Moderate to vigorous intensity physical activity associated with lower risk of death in older women

Roundworms may provide new clues to nicotine dependence

Research shows high risk for cardiovascular and kidney disease in people with HIV

Research reveals impact of helpful strain of bacteria on infants’ digestive tract

Immune system plays surprising role in the aftermath of heart attacks, study finds

Fat hormone associated with NASH may be effective target for therapeutic intervention

UofL researchers help discover new autoimmune disease that causes kidney failure

ACADIA Pharmaceuticals announces results from Phase II study of antipsychotic in Alzheimer's disease psychosis

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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